diff --git a/Lib/test/support/__init__.py b/Lib/test/support/__init__.py
index 3062ec6588fd16..c2287b3fb1cd90 100644
--- a/Lib/test/support/__init__.py
+++ b/Lib/test/support/__init__.py
@@ -2425,10 +2425,10 @@ def _findwheel(pkgname):
     raise FileNotFoundError(f"No wheel for {pkgname} found in {wheel_dir}")
 
 
-# Context manager that creates a virtual environment, install setuptools and wheel in it
+# Context manager that creates a virtual environment, install setuptools in it
 # and returns the path to the venv directory and the path to the python executable
 @contextlib.contextmanager
-def setup_venv_with_pip_setuptools_wheel(venv_dir):
+def setup_venv_with_pip_setuptools(venv_dir):
     import shlex
     import subprocess
     from .os_helper import temp_cwd
@@ -2460,8 +2460,7 @@ def run_command(cmd):
 
         cmd = [python, '-X', 'dev',
                '-m', 'pip', 'install',
-               _findwheel('setuptools'),
-               _findwheel('wheel')]
+               _findwheel('setuptools')]
         run_command(cmd)
 
         yield python
diff --git a/Lib/test/test_cext/__init__.py b/Lib/test/test_cext/__init__.py
index 402a2d04fa875e..46fde541494aa3 100644
--- a/Lib/test/test_cext/__init__.py
+++ b/Lib/test/test_cext/__init__.py
@@ -53,7 +53,7 @@ def test_build_limited_c11(self):
 
     def check_build(self, extension_name, std=None, limited=False):
         venv_dir = 'env'
-        with support.setup_venv_with_pip_setuptools_wheel(venv_dir) as python_exe:
+        with support.setup_venv_with_pip_setuptools(venv_dir) as python_exe:
             self._check_build(extension_name, python_exe,
                               std=std, limited=limited)
 
diff --git a/Lib/test/test_cppext/__init__.py b/Lib/test/test_cppext/__init__.py
index 13f9ea1c56cca5..2b7adac4bccd15 100644
--- a/Lib/test/test_cppext/__init__.py
+++ b/Lib/test/test_cppext/__init__.py
@@ -54,7 +54,7 @@ def test_build_limited(self):
 
     def check_build(self, extension_name, std=None, limited=False):
         venv_dir = 'env'
-        with support.setup_venv_with_pip_setuptools_wheel(venv_dir) as python_exe:
+        with support.setup_venv_with_pip_setuptools(venv_dir) as python_exe:
             self._check_build(extension_name, python_exe,
                               std=std, limited=limited)
 
diff --git a/Lib/test/test_cppext/setup.py b/Lib/test/test_cppext/setup.py
index b30c9e2746c980..ea1ed64bf7ab0a 100644
--- a/Lib/test/test_cppext/setup.py
+++ b/Lib/test/test_cppext/setup.py
@@ -3,6 +3,7 @@
 import os
 import platform
 import shlex
+import sys
 import sysconfig
 from test import support
 
diff --git a/Lib/test/test_peg_generator/test_c_parser.py b/Lib/test/test_peg_generator/test_c_parser.py
index 1411e55dd0f293..1095e7303c188f 100644
--- a/Lib/test/test_peg_generator/test_c_parser.py
+++ b/Lib/test/test_peg_generator/test_c_parser.py
@@ -99,7 +99,7 @@ def setUpClass(cls):
         cls.addClassCleanup(shutil.rmtree, cls.library_dir)
 
         with contextlib.ExitStack() as stack:
-            python_exe = stack.enter_context(support.setup_venv_with_pip_setuptools_wheel("venv"))
+            python_exe = stack.enter_context(support.setup_venv_with_pip_setuptools("venv"))
             sitepackages = subprocess.check_output(
                 [python_exe, "-c", "import sysconfig; print(sysconfig.get_path('platlib'))"],
                 text=True,
diff --git a/Lib/test/wheeldata/setuptools-67.6.1-py3-none-any.whl b/Lib/test/wheeldata/setuptools-67.6.1-py3-none-any.whl
deleted file mode 100644
index 4b7ffd2e49e155..00000000000000
Binary files a/Lib/test/wheeldata/setuptools-67.6.1-py3-none-any.whl and /dev/null differ
diff --git a/Lib/test/wheeldata/setuptools-78.1.0-py3-none-any.whl b/Lib/test/wheeldata/setuptools-78.1.0-py3-none-any.whl
new file mode 100644
index 00000000000000..a1f43daab7a749
Binary files /dev/null and b/Lib/test/wheeldata/setuptools-78.1.0-py3-none-any.whl differ
diff --git a/Lib/test/wheeldata/wheel-0.43.0-py3-none-any.whl b/Lib/test/wheeldata/wheel-0.43.0-py3-none-any.whl
deleted file mode 100644
index 67e2308717d675..00000000000000
Binary files a/Lib/test/wheeldata/wheel-0.43.0-py3-none-any.whl and /dev/null differ