The in vivo and in vitro fates of OX, 5-CHQ, DCHQ, and ICHQ and also their conjugates were studied in rats (Sawada et al., 1978).
Especially in the presence of [Cu.sup.2+] or [Fe.sup.2+] DCHQ sulfate and ICHQ sulfate which were extremely stable in the enzymatic hydrolysis were unstable.
The radio chromatogram, and ultraviolet and infrared spectra gave the identity between urinary metabolites (free or conjugated) and 5-CHQ and DCHQ of the original product.
According to the
DCHQ, there are approximately 1,200 non-governmental organizations operating in Iran that are active in prevention and treatment, and provide nearly 80 percent of all services in these fields.