A validated liquid chromatography-tandem mass spectrometry method was used to assay morphine and
M6G in plasma.
A study in mice genetically lacking ABCC3 revealed that this transporter is involved in the efflux of M3G and
M6G from the liver to the bloodstream (37).
* Correspondence to: Allenna Leonard, The Complementary Set, 34 Palmerston Square Toronto, Ontario
M6G 2S7, Canada.
CeNeS now plans instead to take the morphine-based pain treatment,
M6G, into phase III trials on its own.
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CeNeS said that after the restructuring it would focus on sales and marketing of pharmaceuticals through its UK hospital sales force in the short term, and developing its lead pain treatment
M6G.
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