RRP1B
RRP1B, skraćena verzija od homolog B proteina 1 kodiranog prerađenom ribosomskom RNK, znan i kao KIAA0179, jest ljudski gen sa hromosoma 21.[5]
Aminokiselinska sekvenca
urediDužina polipeptidnog lanca je 758 aminokiselina, a molekulska težina 84.428 Da.[5]
10 | 20 | 30 | 40 | 50 | ||||
---|---|---|---|---|---|---|---|---|
MAPAMQPAEI | QFAQRLASSE | KGIRDRAVKK | LRQYISVKTQ | RETGGFSQEE | ||||
LLKIWKGLFY | CMWVQDEPLL | QEELANTIAQ | LVHAVNNSAA | QHLFIQTFWQ | ||||
TMNREWKGID | RLRLDKYYML | IRLVLRQSFE | VLKRNGWEES | RIKVFLDVLM | ||||
KEVLCPESQS | PNGVRFHFID | IYLDELSKVG | GKELLADQNL | KFIDPFCKIA | ||||
AKTKDHTLVQ | TIARGVFEAI | VDQSPFVPEE | TMEEQKTKVG | DGDLSAEEIP | ||||
ENEVSLRRAV | SKKKTALGKN | HSRKDGLSDE | RGRDDCGTFE | DTGPLLQFDY | ||||
KAVADRLLEM | TSRKNTPHFN | RKRLSKLIKK | FQDLSEGSSI | SQLSFAEDIS | ||||
ADEDDQILSQ | GKHKKKGNKL | LEKTNLEKEK | GSRVFCVEEE | DSESSLQKRR | ||||
RKKKKKHHLQ | PENPGPGGAA | PSLEQNRGRE | PEASGLKALK | ARVAEPGAEA | ||||
TSSTGEESGS | EHPPAVPMHN | KRKRPRKKSP | RAHREMLESA | VLPPEDMSQS | ||||
GPSGSHPQGP | RGSPTGGAQL | LKRKRKLGVV | PVNGSGLSTP | AWPPLQQEGP | ||||
PTGPAEGANS | HTTLPQRRRL | QKKKAGPGSL | ELCGLPSQKT | ASLKKRKKMR | ||||
VMSNLVEHNG | VLESEAGQPQ | ALGSSGTCSS | LKKQKLRAES | DFVKFDTPFL | ||||
PKPLFFRRAK | SSTATHPPGP | AVQLNKTPSS | SKKVTFGLNR | NMTAEFKKTD | ||||
KSILVSPTGP | SRVAFDPEQK | PLHGVLKTPT | SSPASSPLVA | KKPLTTTPRR | ||||
RPRAMDFF |
Reference
uredi- ^ a b c GRCh38: Ensembl release 89: ENSG00000160208 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000058392 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ a b "Entrez Gene: KIAA0179 KIAA0179".
Dopunska literatura
uredi- Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (novembar 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
- Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP (oktobar 2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nature Biotechnology. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
- Hu YH, Warnatz HJ, Vanhecke D, Wagner F, Fiebitz A, Thamm S, Kahlem P, Lehrach H, Yaspo ML, Janitz M (juni 2006). "Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins". BMC Genomics. 7: 155. doi:10.1186/1471-2164-7-155. PMC 1526728. PMID 16780588.
- Nousiainen M, Silljé HH, Sauer G, Nigg EA, Körner R (april 2006). "Phosphoproteome analysis of the human mitotic spindle". Proceedings of the National Academy of Sciences of the United States of America. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
- Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M (januar 2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
- Lehner B, Sanderson CM (juli 2004). "A protein interaction framework for human mRNA degradation". Genome Research. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.
- Scherl A, Couté Y, Déon C, Callé A, Kindbeiter K, Sanchez JC, Greco A, Hochstrasser D, Diaz JJ (novembar 2002). "Functional proteomic analysis of human nucleolus". Molecular Biology of the Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
- Andersen JS, Lyon CE, Fox AH, Leung AK, Lam YW, Steen H, Mann M, Lamond AI (januar 2002). "Directed proteomic analysis of the human nucleolus". Current Biology. 12 (1): 1–11. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
- Nagase T, Seki N, Ishikawa K, Tanaka A, Nomura N (februar 1996). "Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1". DNA Research. 3 (1): 17–24. doi:10.1093/dnares/3.1.17. PMID 8724849.