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The emerging phenomenon of electronic cigarettes has raised concerns among the health community, pharmaceutical industry, health regulators and state governments.<ref name=Saitta2014/> Some jurisdictions are now prohibiting or regulating the use of e-cigarettes in public spaces.
Because of the relative novelty of the technology and the possible relationship to tobacco laws and medical drug policies, electronic cigarette legislation and public health investigations are currently pending in many countries.<ref name=Etter2011/> With respect to determining legislation, regulators are examining the limited data at hand on e-cigarettes.<ref name=Rahman2014/> {{Asof|2014}}, they are largely unregulated.<ref name=Rom2014>{{cite journal|last1=Rom|first1=Oren|last2=Pecorelli|first2=Alessandra|last3=Valacchi|first3=Giuseppe|last4=Reznick|first4=Abraham Z.|title=Are E-cigarettes a safe and good alternative to cigarette smoking?|journal=Annals of the New York Academy of Sciences|year=2014|pages=n/a–n/a|issn=00778923|doi=10.1111/nyas.12609|pmid=25557889}}</ref> Current regulations vary widely, from regions with no regulations to others [[ban (law)|banning]] the devices entirely.<ref name=Etter2011>{{cite journal|last1=Etter|first1=J. F.|last2=Bullen|first2=C.|last3=Flouris|first3=A. D.|last4=Laugesen|first4=M.|last5=Eissenberg|first5=T.|title=Electronic nicotine delivery systems: a research agenda|journal=Tobacco control|date=May 2011|volume=20|issue=3|pages=243–8|pmid=21415064|doi=10.1136/tc.2010.042168|pmc=3215262}}</ref> For example, some countries such as Brazil, Canada, Singapore, the Seychelles, and Uruguay have banned e-cigarettes.<ref name=Grana2014/> {{Asof|2015}}, e-cigarettes are legal for minors to buy in many states in the U.S.<ref name=England2015>{{cite journal|last1=England|first1=Lucinda J.|last2=Bunnell|first2=Rebecca E.|last3=Pechacek|first3=Terry F.|last4=Tong|first4=Van T.|last5=McAfee|first5=Tim A.|title=Nicotine and the Developing Human|journal=American Journal of Preventive Medicine|year=2015|issn=07493797|doi=10.1016/j.amepre.2015.01.015|pmid=25794473}}</ref> {{Asof|2015}}, since e-cigarettes do not contain tobacco, they are not subject to restrictions from using commercials in the U.S.<ref name=MaloneyCappella2015>{{cite journal|last1=Maloney|first1=Erin K.|last2=Cappella|first2=Joseph N.|title=Does Vaping in E-Cigarette Advertisements Affect Tobacco Smoking Urge, Intentions, and Perceptions in Daily, Intermittent, and Former Smokers?|journal=Health Communication|year=2015|pages=1–10|issn=1041-0236|doi=10.1080/10410236.2014.993496|pmid=25758192}}</ref> E-cigarettes have been listed as "drug delivery devices" in several countries because they contain nicotine, and their advertising has been monetarily restricted until safety and efficacy [[clinical trial]]s are conclusive.<ref name=Cervellin2013/> A 2014 review stated that the regulation of these products should be examined in view of the "reported adverse health effects".<ref name=Bekki2014/> In some countries, e-cigarettes are regulated as a [[medical device]]
In the fall of 2013, the electronic cigarette industry ran "a determined lobbying campaign, marrying corporate interests in a fledgling but fast-growing industry with voices elicited from the general public" to defeat proposed European legislation to regulate e-cigarettes like medical devices.<ref name=Higgins2013>{{cite news|author=Andrew Higgins|title=Aided by Army of 'Vapers', E-Cigarette Industry Woos and Wins Europe|url=http://www.nytimes.com/2013/11/10/world/europe/aided-by-army-of-vapers-e-cigarette-industry-woos-and-wins-europe.html|accessdate=22 November 2014|publisher=The New York Times|date=9 November 2013}}</ref> Pharmaceutical manufacturers GlaxoSmithKline and Johnson & Johnson have lobbied the US government, the FDA, and the EU parliament for stricter regulation of e-cigarettes which compete with their products [[Nicorette]] gum and [[nicotine patch]]es.<ref name=Kitamura2014>{{cite news|author1=Makiko Kitamura|title=Glaxo Memo Shows Drug Industry Lobbying on E-Cigarettes|url=http://www.bloomberg.com/news/2014-02-19/glaxo-memo-shows-drug-industry-lobbying-on-e-cigarettes.html|accessdate=22 November 2014|publisher=Bloomberg News|date=19 February 2014}}</ref>
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