Sulfopropanediol 3-dehydrogenase (EC 1.1.1.308, DHPS 3-dehydrogenase (sulfolactate forming), 2,3-dihydroxypropane-1-sulfonate 3-dehydrogenase (sulfolactate forming), dihydroxypropanesulfonate 3-dehydrogenase, hpsN (gene)) is an enzyme with systematic name (R)-2,3-dihydroxypropane-1-sulfonate:NAD+ 3-oxidoreductase.[1] This enzyme catalyses the following chemical reaction
| Sulfopropanediol 3-dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.308 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- (R)-2,3-dihydroxypropane-1-sulfonate + 2 NAD+ + H2O (R)-3-sulfolactate + 2 NADH + 2 H+
The enzyme is involved in degradation of (R)-2,3-dihydroxypropanesulfonate.
References
edit- ^ Mayer J, Huhn T, Habeck M, Denger K, Hollemeyer K, Cook AM (May 2010). "2,3-Dihydroxypropane-1-sulfonate degraded by Cupriavidus pinatubonensis JMP134: purification of dihydroxypropanesulfonate 3-dehydrogenase". Microbiology. 156 (Pt 5): 1556–64. doi:10.1099/mic.0.037580-0. PMID 20150239.
External links
edit- Sulfopropanediol+3-dehydrogenase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
