ligand

In the present work, we decided to investigate conductometric and spectrophotometric studies and the effect of the ligands structure on the stability constants of the complexation of the some metal ions with a pyrazoloisoindol derivative ligand.

The polymer-supported ligands are prepared as chemically modified with various monomers.

Many research teams have embraced the phenanthroline (phen) structure into the synthesis of a variety of polypyridyl ligands with different end group positions in the phenyl ring, developed on from the planar ligand; 2-phenyl-imidazo[4,5-f]1,10-phenanthroline (PIP) consists of a basic phenyl ring.

To describe the kinetic behavior of this complex process, a system of ordinary differential equations was derived (see Section 2), and the numerical solution of these equations yielded a series of characteristic plots, demonstrating the dependence of the rate of the reporter ligand binding on the concentrations of ligands A and B.

The McGhee and von Hippel model which takes into account the MI between nearest neighbouring bound ligands has been the most widely used [21] in combination with the Scatchard equation for description of small molecules with homogeneous polymers.

In an attempt to improve the bioavailability and to leverage the Th1-inducing potential of TLR2 and TLR7 ligands, we investigated three different, commercially available, synthetic dual TLR2/7 ligands: CL401, CL413, and CL531.

Two choices for prefiltering ligands were used: prefiltering using Lipinski's Rule of 5 and removing ligands with reactive functional groups.

c.) General Synthesis of Mixed Ligand Metal Complexes by magnetic stirring: Solution of metal salt (Cobalt Nitrate) (1 mmol) and ligands - Sarcosine (1 mmol) and 1,10- phenanthroline (2 mmol) were prepared.