Historically Rattus species (both black and brown rats) have been implicated in the emergence and spread of infectious diseases of human health importance such as plague, murine typhus, scrub typhus, leptospirosis and hemorrhagic fever.
In this region, seropositivity has been reported in synanthropic rodents (Rattusrattus and Mus musculus) from 37.5 to 47%, suggesting that these animals act as hosts for the parasite in urban cycles [5, 6].
Para os roedores aloctones Rattus norvegicus (Berkenhout, 1769) e Rattusrattus (Linnaeus, 1758) foram utilizados pelos de um individuo de cada especie, alem de amostras de dois individuos de Mus musculus (Linnaeus, 1758).
Conclusion: According to the experiment, it can be concluded that ethanol extract 96% of soursop Annona muricata L.) leaves with the concentration 5%, 15%, 25% can decrease the total plasma cholesterol rates in rat (Rattus norvegicus L.)