Retrovir

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Related to Retrovir: retrovirus, AZT, zidovudine

Retrovir

(ˈrɛtrəʊˌvɪə)

(Pharmacology) trademark a brand of the drug zidovudine

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

Ret•ro•vir

(ˈrɛ troʊˌvɪər)

Trademark. the international brand name for azidothymidine. Compare AZT, zidovudine.

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Noun

Retrovir - an antiviral drug (trade name Retrovir) used in the treatment of AIDS; adverse side effects include liver damage and suppression of the bone marrow

AZT, ZDV, zidovudine

NRTI, nucleoside reverse transcriptase inhibitor - an antiviral drug used against HIV; is incorporated into the DNA of the virus and stops the building process; results in incomplete DNA that cannot create a new virus; often used in combination with other drugs

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His laboratory played a major role in developing the first three agents approved by FDA specifically to treat AIDS: Retrovir (AZT), Videx (ddI) and HIVID(ddC) and laid the foundation for many other therapies.

NeuBase Therapeutics Announces Addition of Industry Pioneer Dr. Samuel Broder and World-Renowned Geneticist Dr. George Church to Scientific Advisory Board

His laboratory played a major role in developing the first 3 agents approved by FDA specifically to treat the AIDS virus, Retrovir, Videx, and HIVID.

Sensei Biotherapeutics Names Former Head of the National Cancer Institute to its Board of Directors

Since the first anti-HIV drug, GlaxoSmithKline's (GSK's) Retrovir (azidothymidine), was approved in 1987, major improvements have been made in the field of antiretroviral therapy (ART).

PharmaPoint: Human Immunodeficiency Virus (HIV) - Global Drug Forecast and Market Analysis to 2023

Treatment regimens included d4T (stavudine (Zerit)) or AZT (zidovudine (Retrovir)) with 3TC (lamivudine (Epivir)) and either efavirenz (Sustiva or Stocrin) or nevirapine (Viramune).

Big differences in virological outcomes among people taking first-line HIV therapy in resource-limited settings

After randomization, the most commonly selected NRTIs were tenofovir thsoproxil fumarate/emtricitabine (Truvada) (82%) and tenofovir/ emtricitabine/zidovudine (Retrovir) (12%), according to the late-breaking abstract.

Omitting NRTIs may be safe with optimized HIV regimen

(1) But taking Retrovir (zidovudine) raised chances of cardiomyopathy in certain children.

Combination antiretrovirals halve rate of cardiomyopathy in children with HIV

In 1991, Gehrke and Johnsen (24) reported the first case of the bottle caries associated with ART, where a child of two years was associated with use of Retrovir bottle at night and bad oral hygiene.

Oral manifestations in HIV+ children in Mozambique/Manifestacoes orais em criancas HIV, em Mocambique

They include AZT (also known as Retrovir), 3TC (lamivudine or Epivir) and indinavir.

Bahrain 'winning war against Aids'

Additionally, the company said the NDA is based on the reference listed drug Retrovir Tablets, by ViiV Healthcare.

Mylan Inc awarded FDA approval for Zidovudine Tablets, 100 mg to control HIV infection

In children younger than age 13 years who may have difficulty swallowing pills, the staff generally uses 28 days of zidovudine (Retrovir), lamivudine (Epivir), and Kaletra (a combination of lopinavir plus ritonavir), because all are available in liquid formulations.