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NDVis–Neuro

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Encyclopedia of Computational Neuroscience

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Definition

NDVis–neuro is a Java application that enables visualization and analysis of model neuron simulation databases. It is open source and available at http://ndvis.sourceforge.net/. The tool was originally created to visualize the database described in “Alternative to hand-tuning conductance-based models: construction and analysis of databases of model neurons” (Prinz et. al. 2003). It has now been used with a number of different databases generated by simulating neuron models with various input parameters.

Detailed Description

The examples and visualizations shown here are based on the Prinz database referenced above. The neuron model used to create the database contained eight conductance parameters: Na, CaT, CaS, A, KCa, Kd, H, and leak. Each parameter had six possible starting values. A simulation was run for every possible combination of the eight parameter values, yielding 68or 1,679,616 simulations. For each simulation, the conductance parameters served as inputs and...

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References

  • LeBlanc J, Ward MO, Wittels N (1990) Exploring n-dimensional databases. In: VIS’90: Proceedings of the 1st conference on Visualization’90, IEEE Computer Society Press, Los Alamitos, pp 230–237

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  • Prinz AA, Billimoria CP, Marder E (2003) Alternative to hand-tuning conductance-based models: construction and analysis of databases of model neurons. J Neurophysiol 90:3998–4015

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Further Reading

  • Taylor AL, Hickey TJ, Prinz AA, Marder E (2006) Structure and visualization of high-dimensional conductance spaces. J Neurophysiol 96(2):891–905

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Author information

Authors and Affiliations

  1. VisiTrend, Boston, MA, USA

    John Langton Ph.D.

Authors
  1. John Langton Ph.D.
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Corresponding author

Correspondence to John Langton Ph.D. .

Editor information

Editors and Affiliations

  1. Atlanta, Georgia, USA

    Dieter Jaeger

  2. Department of Biomedical Engineering, Florida International University, Miami, Florida, USA

    Ranu Jung

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Langton, J. (2014). NDVis–Neuro. In: Jaeger, D., Jung, R. (eds) Encyclopedia of Computational Neuroscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7320-6_169-1

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  • DOI: https://doi.org/10.1007/978-1-4614-7320-6_169-1

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  • Publisher Name: Springer, New York, NY

  • Online ISBN: 978-1-4614-7320-6

  • eBook Packages: Living Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences

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