Abstract
The mobility of Spanish biochemists from Europe to the United States over the past 80 years (1927–2006) is approached from a historical perspective. The academic community on human genetics has awarded this emigrated Spanish community with the Nobel prize as well as other awards from European foundations. The vertical/horizontal integration methodology offers an opportunity to understand the extremely satisfactory history of a small European community overseas. To piece the puzzle together, continuous reference is made to the theory of systems. To test and use this holistic history, the circulation of the knowledge produced on cancer has been studied as intrinsically related to time by using the algorithmic historiography.
Francisco Duran Reynals and Severo Ochoa have been selected as examples of the vertical integration. The former one because he was the director of an important collaborator, his own wife; the latter, as the founder of a Spanish specific research school in America based in his own work. The simultaneous stay of several young Spanish scientists at the Columbia University (Mariano Barbacid, Manuel Perucho and Ángel Pellicer) serves to design the horizontal integration, to create a holon hierarchy to reflect the criteria of subsidiarity and acceptability, and to focus on the Spanish discoveries and contributions to cancer research.
The transatlantic flows of knowledge generated by the Spanish elite of biochemists in the USA from 1927 on define a network of geographical displacements. As a result, the social structure thus visualizes the identity of the international mobility of scientists who leave for Europe/USA, and their return to Spain. A model of the brain drain of professionals to the USA, that retain 80% of the Spanish cancer researchers, is developed.
Similar content being viewed by others
References
Allen, G.E. (2004), A pact with the embryo: Viktor Hamburger, holistic and mechanistic philosophy in the development of neuroembryology, 1927–1955, Journal of the History of Biology, 37: 421–475.
Anon. (1974), Does cancer research have realistic aims?, Nature, 249: 299–300.
Atlan, H. (1992), L’organisation Biologique et la Théorie de l’Information. Hermann, Paris.
Aubenque, P. (1972), Le Problème de l’Ětre chez Aristote: Essai sur la Problématique Aristotélicienne, Presses Universitaires de France, Paris.
Bertalanffy, L. Von. (1934), Teoría del Desarrollo Biológico: Introducción a la Biología Teórica, Universidad Nacional de La Plata, Buenos Aires.
Bonsack, F. (1990), Ouverture vertical et ouverture horizontale, Bulletin de l’Association Ferdinand Gonseth, 55: 4–5.
Bourret, P., Mogoutov, A., Julian-Reynier, C., Cambrosio A. (2006), A new clinical collective for French cancer genetics: A heterogeneous mapping analysis, Science, Technology, & Human Values, 31 (4): 431–464.
Braun, T., Schubert, A. (2003), A quantitative view on the coming of age of interdisciplinarity in the sciences 1980–1999, Scientometrics, 58 (1): 183–189.
Casacuberta, D., Estany, A. (2003), ¿Eureka?: El Trasfondo de un Descubrimiento sobre el Cáncer y la Genética Molecular, Tusquets, Barcelona.
Casey, T., Mahroum, S., Ducatel, K., Barré, R. (2001), The Mobility of Academic Researchers: Academic Careers & Recruitment in ICT and Biotechnology, IPTS, Seville. http://www.jrc.es/home/pages/detail.cfm?prs=728
Cole, J. R., Cole, S. (1973), Social Stratification in Science, University of Chicago, Chicago.
Coni, N. (2002), Medicine and the Spanish Civil War, Journal of the Royal Society of Medicine, 95: 147–150.
Currás, E. (1988), Implicaciones de la teoría de sistemas. In: E. Currás, La Información en sus Nuevos Aspectos: Ciencias de la Documentación. Madrid, Paraninfo, 1988, pp.140–169.
Currás, E. (2002), Vertical integration of sciences: an approach to a different view of knowledge organization, Journal of Information Science, 28 (5): 417–426.
Dedijer, S. (1964), Migration of scientists: a world-wide phenomenon and problem, Nature, 201 (4923): 964–967.
Dulbecco, R. (1976), From the molecular biology of oncogenic DNA viruses to cancer, Science, 192: 437–440.
García-Romero, A., Modrego, A. (2001). Research Training in Spain: An Assessment Exercise. European Commission. ftp://ftp.cordis.europa.eu/pub/improving/docs/ser_conf_bench_garcia-Romero.Pdf
Gish, O., Wilson, J. A. (1970). Emigrating British physicians, Social Studies & Medicine, 3: 495–511.
Goranson, T. (1998), Mailing Received on Sat Sep 26 17:54:41. http://fis.icts.sbg.ac.at/mailings/0148.html
Hohlfeld, R. (1983). Cancer research. A study of praxis-related theoretical developments in chemistry, the biosciences and medicine. In: W. Schäfer (Ed.), Finalization in Science: The Social Orientation of Scientific Progress, D. Reidel Publishing Company, pp. 93–126.
Kiselev, F. L. (1990), Molecular oncology. In: R. V. Petrov (Ed.), Medical Dimensions of Molecular Biology, Nauka, 1990.
Kohler, R. E. (1973), The enzyme theory and the origin of biochemistry, Isis, 64 (222): 181–196.
Larraga, V. E. (2003), La pérdida de talentos científicos en. España, DT 22/2003, Fundación Alternativas, Madrid, 2003. http://www.falternativas.org/base/download/07b2_08-09-05_22_2003.pdf
Laudel, G. (2003), Studying the brain drain: can bibliometric methods help?, Scientometrics, 57 (2): 215–237.
Llavona, R., Bandrés, J. (2003), Francisco Grande Covián y la psicología, Psicothema, 15 (3): 345–351. http://www.psicothema.com/psicothema.asp?ID=1071
Malecky, I., Olszewski, E. (1980), Regularities in the development of contemporary science. In: B. Barnes (Ed.), Estudios Sobre Sociología de la Ciencia: Regularidades en el Desarrollo de la Ciencia Contemporánea. Alianza, 1980. (originally published by: Organon, vol 13, pp. 193–212.)
Marra, G., Boland, C. R. (1995), Hereditary nonpolyposis colorectal cancer: the syndrome, the genes, and historical perspectives, Journal of the National Cancer Institute, 87 (15): 1114–1125.
Meyer, S. C. (2004), The origin of biological information and the higher taxonomic categories, Proceedings of the Biological Society of Washington, 117 (2): 213–239.
Morange, M. (1997), From the regulatory vision of cancer to the oncogene paradigm, 1975–1985, Journal of the History of Biology, 30: 1–29.
Nalimov, V. V. (1981), Faces to Science, ISI Press, Philadelphia, p.250.
Pellicer, À. (2005), Bases moleculars del càncer. In: Díssetè Congrés de Metges i Biòlegs de Llengua Catalana. Fundació Alsina i Bofill, pp. 15–28. http://alsina-bofill.iecat.net/documents/ponencies17congres/03%20Pellicer%20Pag%2015_28.pdf
Pellicer, Á. (2004), Contribución de los científicos españoles n Estados Unidos a la bioquímica. In: E. Muñoz (Dir.), Cuarenta Años de la Sociedad Española de Bioquímica y Biología Molecular. Sociedad Estatal de Conmemoraciones Culturales, pp. 227–248.
Pierson, A. S., Cotgreave, P. (2000), Citation figures suggest that the UK brain drain is a genuine problem, Nature, 407 (6800): 13.
Price, D. J. S. (1965), The scientific foundations of science policy, Nature, 206 (4981): 233–238.
Rodríguez-Ocaña, E. (2005), E. MUñOZ (dir.), M. J. Santesmases, A. Romero, J. Ávila (Eds). Cuarenta años de la Sociedad Española de Bioquímica y Biología Molecular (1963–2003), Madrid, Sociedad Estatal de Conmemoraciones Culturales, S.A., 2004, 362 pp. ISBN: 84-95486-79-02., Dynamis. Acta Hisp. Med. Sci. Hist. Illus., 25: 576–578. (Review.)
Scherer, F. M. (2000), The emigration of German-speaking economists after 1933, Journal of Economic Literature, XXXVIII: 614–626.
Shimkin, M. B. (1974), History of cancer research: a starter reading list and guide, Cancer Research, 34: 1519–1520.
Smith, T. F., Waterman, M. S. (1981), Overlapping genes and information theory, Journal of Theoretical Biology, 91: 379–380.
Stichweh, R. (2000), Systems theory as an alternative to action theory? The rise of ‘communication’ as a theoretical option, Acta Sociologica, 43 (1): 5–13.
Stoker, M. (1975), Limits to oncology, Nature, 254: 547–548.
Szelényi, K. (2003), Explaining the migration and settlement of foreign graduate students: global integration theory and the theory of cumulative causation, UCLA Center for Comparative and Global Research. http://www.international.ucla.edu/cms/files/katipaper.doc
Triolo, V. A., Riegel, I. L. (1961), The American Association for Cancer Research, 1907–1940. Historical review, Cancer Research, 21 (2): 137–167.
Trist, E. (1973), Organizaçao e Financiamento da Investigaçao, Livraria Bertrand, Lisboa.
Witkowski, J. A. (1986), Somatic cell hybrids: a fusion of biochemistry, cell biology and genetics, Trends in Biochemistry Sciences, 11: 149–152.
Wulff, E. (1996A), Historia del descubrimiento del orígen de la formación de los tumores: el programa del Dr. Barbacid en los albores de los estudios sobre oncogénesis, Llull, 19: 525–549.
Wulff, E. (1996B), The natural history of the discovery of hereditary carcinogenesis of the colon — Scientific dynamics in information flow, Arbor, CLIV (608): 9–31. [In Spanish.]
Wulff, E. (2006), La familia trk de receptores de las neurotrofinas y el receptor p75, un caso de caracterización de hipótesis múltiples en la historia del factor de crecimiento nervioso (NGF). In: Actas IX Congreso de la Sociedad Española de Historia de las Ciencias y de las Técnicas. Cádiz.
Zuckerkandl, E., Pauling, L. (1965), Molecules as documents of evolutionary history, Journal of Theoretical Biology, 8 (2): 357–366. http://profiles.nlm.nih.gov/MM/B/B/N/V/_/mmbbnv.pdf
Author information
Authors and Affiliations
Corresponding author
Additional information
A version of theis paper was a contribution to: 2nd International Conference of the European Society for the History of Science (Cracow, Sept. 2006).
Rights and permissions
About this article
Cite this article
Currás, E., Barreiro, E.W. Integration in Europe of human genetics results obtained by Spaniards in the USA: A historical perspective. Scientometrics 75, 473–493 (2008). https://doi.org/10.1007/s11192-007-1861-2
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11192-007-1861-2