Active Immunization of Chicks against Plasmodium gallinaceum by Inactivated Homologous Sporozoites and Erythrocytic Parasites

Abstract

THIS work is a continuation of the investigation of immunization against malaria carried out previously^1–4. In the present work, Sporozoites and erythrocytic forms of Plasmodium gallinaceum which had been treated by four different methods were used as antigens to immunize fowls. Sera from the immunized birds were tested for agglutination of homologous sporozoites. The birds were also challenged by inoculation with normal, virulent sporozoites and erythrocytic forms of the same strain of P. gallinaceum.