SNP genotyping platforms have been used to discover ∼1,000 deletion structural variants within the human genome, with median lengths ranging from 500 bp to 10.5 kb. Analyses of a subset of these provide compelling evidence of linkage disequilibrium with flanking SNPs.
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Katie Ris
References
Hinds, D.A. et al. Science 307, 1072–1079 (2005).
The International HapMap Consortium. Nature 437, 1299–1320 (2005).
Hinds, D.A., Kloek, A.P. & Frazer, K.A. Nat. Genet. 38, 82–85 (2006).
Conrad, D.F., Andrews, T.D., Carter, N.P., Hurles, M.E. & Pritchard, J.K. Nat. Genet. 38, 75–81 (2006).
McCarroll, S.A. et al. Nat. Genet. 38, 86–92 (2006).
Tuzun, E. et al. Nat. Genet. 37, 727–732 (2005).
Sebat, J. et al. Science 305, 525–528 (2004).
Iafrate, A.J. et al. Nat. Genet. 36, 949–951 (2004).
Sharp, A.J. et al. Am. J. Hum. Genet. 77, 78–88 (2005).
Bailey, J.A. et al. Science 297, 1003–1007 (2002).
Stankiewicz, P. et al. Cold Spring Harb. Symp. Quant. Biol. 68, 445–454 (2003).
Bhangale, T.R., Rieder, M.J., Livingston, R.J. & Nickerson, D.A. Hum. Mol. Genet. 14, 59–69 (2005).
Fredman, D. et al. Nat. Genet. 36, 861–866 (2004).
Frazer, K.A. et al. Genome Res. 13, 341–346 (2003).
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Eichler, E. Widening the spectrum of human genetic variation. Nat Genet 38, 9–11 (2006). https://doi.org/10.1038/ng0106-9
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DOI: https://doi.org/10.1038/ng0106-9
