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Shutting down Wnt signal–activated cancer

New evidence suggests that Wnt signaling can be suppressed or further activated by upstream signals, even though the pathway seems to be constitutively activated by downstream mutations in cancer cells.

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Figure 1: Quantitative control of the canonical Wnt pathway.

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Taketo, M. Shutting down Wnt signal–activated cancer. Nat Genet 36, 320–322 (2004). https://doi.org/10.1038/ng0404-320

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