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Body fatness: Longitudinal relationship of body mass index and the sum of skinfolds with other risk factors for coronary heart disease

International Journal of Obesity volume 22, pages 915–922 (1998)Cite this article

Abstract

OBJECTIVE: To analyse the longitudinal relationships between body mass index (BMI)/sum of skinfolds (SSF) and biological and lifestyle risk factors for coronary heart disease (CHD).

DESIGN: An observational longitudinal study; that is, the Amsterdam Growth and Health Study.

SUBJECTS: 181 males and females, initially aged 13 y. Over a period of 15 y, six repeated measurements were carried out.

MEASUREMENTS: BMI and SSF, biological CHD risk factors; that is, total cholesterol (TC), high density lipoprotein (HDL), TC:HDL ratio, systolic/diastolic blood pressure (SBP/DBP) and cardiopulmonary fitness (V˙O2-max) and lifestyle CHD risk factors (that is, daily physical activity, dietary parameters, smoking, and alcohol consumption). The longitudinal relationships were analysed by an autoregressive model, in which the value of the outcome variable at time-point t is not only related to the value of the predictor variable at t, but also to the value of the outcome variable at t−1.

RESULTS: Both BMI and SSF were positively related to TC and the TC:HDL ratio. Only BMI was positively related to SBP and only SSF was negatively related to V˙O2-max. Physical activity was negatively related to SSF. None of the other lifestyle parameters were related to SSF and/or BMI.

CONCLUSIONS: Both BMI and SSF were related to a high risk profile regarding CHD. Different relationships for SSF and BMI are found, because BMI not only reflects body fatness, but also lean body mass. Analyses with BMI as an indicator for body fatness should therefore be interpreted cautiously.

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Authors and Affiliations

  1. Institute for Research in Extramural Medicine, Faculty of Medicine, Vrije Universiteit, Amsterdam, The Netherlands

    JWR Twisk, HCG Kemper, W van Mechelen, GB Post & FJ van Lenthe

  2. Department of Social Medicine, Faculty of Medicine, Vrije Universiteit, Amsterdam, The Netherlands

    W van Mechelen

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  1. JWR Twisk
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  2. HCG Kemper
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  3. W van Mechelen
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  4. GB Post
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  5. FJ van Lenthe
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Twisk, J., Kemper, H., van Mechelen, W. et al. Body fatness: Longitudinal relationship of body mass index and the sum of skinfolds with other risk factors for coronary heart disease. Int J Obes 22, 915–922 (1998). https://doi.org/10.1038/sj.ijo.0800695

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  • DOI: https://doi.org/10.1038/sj.ijo.0800695

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