Most myeloid cells express the growth-factor receptor CSF1R. Recognition of interleukin 34 by CSF1R is required for the development of tissue-resident Langerhans cells and microglia, which explains the independence of their growth from CSF1.
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Katie Vicari
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Zelante, T., Ricciardi-Castagnoli, P. The yin-yang nature of CSF1R-binding cytokines. Nat Immunol 13, 717–719 (2012). https://doi.org/10.1038/ni.2375
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DOI: https://doi.org/10.1038/ni.2375
