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== Toxicology ==
Chlordecone can accumulate in the liver and the distribution in the human body is regulated by binding of the pollutant or its metabolites to [[Lipoprotein|lipoproteins]] like [[Low-density lipoprotein|LDL]] and [[High-density lipoprotein|HDL]].<ref>{{cite journal |last1=Delannoy |first1=Matthieu |last2=Girardet |first2=Jean-Michel |last3=Djelti |first3=Fathia |last4=Yen |first4=Frances T. |last5=Cakir-Kiefer |first5=Céline |title=Affinity of chlordecone and chlordecol for human serum lipoproteins |journal=Environmental Toxicology and Pharmacology |date=1 November 2020 |volume=80 |pages=103486 |doi=10.1016/j.etap.2020.103486 |pmid=32891758 |s2cid=221523766 |url=https://hal.univ-lorraine.fr/hal-02925906/file/Delannoy%20et%20al.%20draft%20sent%20to%20editorial%20preprint%281%29.pdf }}</ref>
The LC<sub>50</sub> (LC = lethal concentration) is 35 μg/ L for ''[[Etroplus maculatus]]'',<ref>{{cite journal |last1=Asifa |first1=K. P. |last2=Chitra |first2=K. C. |year=2013 |title=Determination of median lethal concentration (LC50) and behavioral effects of chlordecone in the cichlid fish, Etroplus maculatus |journal=International Journal of Science and Research |volume=4 |issue=3 |pages=1473–1475 |url=https://www.ijsr.net/archive/v4i3/SUB152402.pdf }}</ref> 22–95 μg/kg for [[blue gill]] and [[trout]]. Chlordecone [[bioaccumulate]]s in animals by factors up to a million-fold.
Workers with repeated exposure suffer severe [[convulsions]] resulting from degradation of the [[synaptic junctions]].<ref name=Ullmann2/>
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