Ganaxolone is aan [[structural analog|analog]] of the neuroactive steroid [[allopregnanolone]] which possesses no known hormonal activity and, instead, is thought to primarily function by binding to GABAa receptors as a positive allosteric modulator.<ref>{{cite web |title=PubChem compound summary for ganaxolone |url=https://pubchem.ncbi.nlm.nih.gov/compound/6918305 |website=PubChem databade |publisher=National Library of Medicine (National Center for Biotechnology Information) |access-date=6 August 2022}}</ref>
Other pregnane neurosteroids include [[alfadolone]], [[alfaxolone]], [[allopregnanolone]] (brexanolone), [[hydroxydione]], [[minaxolone]], [[pregnanolone]] (eltanolone), and [[renanolone]], among others.
