Glycopeptide antibiotic: Difference between revisions

Some members of this class of drugs inhibit the synthesis of cell walls in susceptible microbes by inhibiting [[peptidoglycan]] synthesis. They bind to the amino acids within the cell wall preventing the addition of new units to the peptidoglycan. In particular, they bind to acyl-D-alanyl-D-alanine in peptidoglycan. Many peptidoglycansglycopeptides inhibit the function of glycosyltransferases, which polymerase amino acid/sugar building blocks into peptidoglycan.