Vachellia rigidula: Difference between revisions

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phenethylamine, tryptamine, tyramine, and β-Methylphenethylamine (that it can be misidentified as amphetamine). - pmid 24176750. Removed methamphetamine (no cite)
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== Phytochemistry ==
A phytochemical study of ''V. rigidula''<ref>{{cite journal |doi=10.1016/S0031-9422(97)01022-4 |title=Toxic amines and alkaloids from acacia rigidula |journal=Phytochemistry |volume=49 |issue=5 |pages=1377–80 |year=1998 |last1=Clement |first1=Beverly A |last2=Goff |first2=Christina M |last3=Forbes |first3=T.David A }}</ref> by workers at the Texas A & M University Agricultural Research and Extension Center at Uvalde, TX, reported the presence of over forty [[alkaloids]], including low amounts (up to around 15&nbsp;ppm) of several [[amphetamines]] that had previously been found by the same research group in the related species ''[[Senegalia berlandieri]]'',<ref>{{cite journal |doi=10.1016/S0031-9422(97)00240-9 |title=Toxic amines and alkaloids from Acacia berlandieri |journal=Phytochemistry |volume=46 |issue=2 |pages=249–54 |year=1997 |last1=Clement |first1=Beverly A. |last2=Goff |first2=Christina M. |last3=Forbes |first3=T. David A. }}</ref> but which otherwise are known only as products of laboratory synthesis. Compounds found in the highest concentrations (ranging from a few hundred to a few thousand ppm) were [[phenethylamine]], [[N-methylphenethylamine|''N''-methylphenethylaminetryptamine]], [[tyramine]], and [[N-methyltyramine|''N''β-methyltyramineMethylphenethylamine]] (that it can be misidentified as amphetamine).<ref>{{cite journal |last1=Pawar |first1=RS |last2=Grundel |first2=E |last3=Fardin-Kia |first3=AR |last4=Rader |first4=JI |title=Determination of selected biogenic amines in Acacia rigidula plant materials and dietary supplements using LC-MS/MS methods. |journal=Journal of pharmaceutical and biomedical analysis |date=January 2014 |volume=88 |pages=457-66 |doi=10.1016/j.jpba.2013.09.012 |pmid=24176750}}</ref> Other notable compounds reported were [[N,N-dimethyltryptamine|''N'',''N''-dimethyltryptamine]], [[mescaline]], [[amphetamine]], [[methamphetamine]] and [[nicotine]], although these were found in low concentrations (e.g. mescaline at 3-28 ppm).
 
The presence of such an unprecedented chemical range of [[psychoactive]] compounds, including ones not previously found in nature, in a single plant species has led to the suggestion that some of these findings may have resulted from cross-contamination or were possibly artifacts of the analytical technique.<ref>{{cite web |url=http://www.cognitiveliberty.org/shulgin/adsarchive/acacia.htm |work=Ask Dr. Shulgin Online |title=Acacias and Natural Amphetamine |publisher=Center for Cognitive Liberty & Ethics |date=2001-09-26}}</ref>