Cytoglobin: Difference between revisions
Content deleted Content added
No edit summary |
added research section |
||
| Line 9: | Line 9: | ||
| summary_text = Cytoglobin is a ubiquitously expressed [[hexacoordinate]] [[hemoglobin]] that may facilitate diffusion of oxygen through tissues, scavenge [[nitric oxide]] or reactive oxygen species, or serve a protective function during [[oxidative stress]] (Trent and Hargrove, 2002).[supplied by OMIM]<ref name="entrez">{{cite web | title = Entrez Gene: CYGB cytoglobin| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=114757| accessdate = }}</ref> |
| summary_text = Cytoglobin is a ubiquitously expressed [[hexacoordinate]] [[hemoglobin]] that may facilitate diffusion of oxygen through tissues, scavenge [[nitric oxide]] or reactive oxygen species, or serve a protective function during [[oxidative stress]] (Trent and Hargrove, 2002).[supplied by OMIM]<ref name="entrez">{{cite web | title = Entrez Gene: CYGB cytoglobin| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=114757| accessdate = }}</ref> |
||
}} |
}} |
||
==Researches== |
|||
===Biomarker=== |
|||
A recent study found that CYGB expression can be used as a specific marker with which [[hepatic stellate cell]]s can be distinguished from portal myofibroblasts in the damaged human liver. |
|||
<ref name=" pmid = 24296877">{{cite journal | author = Motoyama H | title = Cytoglobin is expressed in hepatic stellate cells, but not in myofibroblasts, in normal and fibrotic human liver. | journal = Lab Invest. | volume = 94 | issue = 2 |date=Feb 2014 | pmid = 24296877 | url = http://www.nature.com/labinvest/journal/v94/n2/full/labinvest2013135a.html | pages = 192-207}}</ref> |
|||
==References== |
==References== |
||
Revision as of 14:41, 28 April 2014
Template:PBB Cytoglobin is the protein product of CYGB, a human and mammalian gene.[1]
Cytoglobin is a globin molecule ubiquitously expressed in all tissues and most notably utilized in marine mammals. It is thought to protect against hypoxia. The predicted function of cytoglobin is the transfer of oxygen from arterial blood to the brain.[2]
Researches
Biomarker
A recent study found that CYGB expression can be used as a specific marker with which hepatic stellate cells can be distinguished from portal myofibroblasts in the damaged human liver. [3]
References
- ^ Cite error: The named reference
entrezwas invoked but never defined (see the help page). - ^ "Why Diving Marine Mammals Resist Brain Damage from Low Oxygen".
- ^ Motoyama H (Feb 2014). "Cytoglobin is expressed in hepatic stellate cells, but not in myofibroblasts, in normal and fibrotic human liver". Lab Invest. 94 (2): 192–207. PMID 24296877.
Further reading
PDB gallery | |
|---|---|
|
External links
- cytoglobin at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
 | This article on a gene on human chromosome 17 is a stub. You can help Wikipedia by expanding it. |