ENZYME entry: EC 2.4.1.41

Accepted Name

polypeptide N-acetylgalactosaminyltransferase

Alternative Name(s)

protein-UDP acetylgalactosaminyltransferase

Reaction catalysed

L-seryl-[protein] + UDP-N-acetyl-alpha-D-galactosamine = a 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP + H(+)
L-threonyl-[protein] + UDP-N-acetyl-alpha-D-galactosamine = a 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP + H(+)

Comment(s)

The glycosyl residue is transferred to threonine or serine hydroxy groups on the polypeptide core of submaxillary mucin, kappa-casein, apofetuin and some other acceptors of high molecular mass.

Cross-references

BRENDA

2.4.1.41

EC2PDB

2.4.1.41

ExplorEnz

2.4.1.41

KEGG Ligand Database for Enzyme Nomenclature

2.4.1.41

IUBMB Enzyme Nomenclature

2.4.1.41

MEDLINE

Find literature relating to 2.4.1.41

MetaCyc

2.4.1.41

Rhea expert-curated reactions

2.4.1.41

UniProtKB/Swiss-Prot

Q07537, GALT1_BOVIN	Q6WV20, GALT1_DROME	Q10472, GALT1_HUMAN
O08912, GALT1_MOUSE	Q29121, GALT1_PIG	Q10473, GALT1_RAT
Q6WV19, GALT2_DROME	Q10471, GALT2_HUMAN	Q6PB93, GALT2_MOUSE
P34678, GALT3_CAEEL	Q9Y117, GALT3_DROME	Q14435, GALT3_HUMAN
P70419, GALT3_MOUSE	H0ZAB5, GALT3_TAEGU	Q8I136, GALT4_CAEEL
Q8IA42, GALT4_DROME	Q8N4A0, GALT4_HUMAN	O08832, GALT4_MOUSE
Q95ZJ1, GALT5_CAEEL	Q6WV17, GALT5_DROME	Q7Z7M9, GALT5_HUMAN
Q8C102, GALT5_MOUSE	O88422, GALT5_RAT	Q5EA41, GALT6_BOVIN
Q6WV16, GALT6_DROME	Q8NCL4, GALT6_HUMAN	Q8C7U7, GALT6_MOUSE
Q8MV48, GALT7_DROME	Q86SF2, GALT7_HUMAN	Q80VA0, GALT7_MOUSE
Q5RFJ6, GALT7_PONAB	Q9R0C5, GALT7_RAT	Q9VUT6, GALT8_DROME
Q9NY28, GALT8_HUMAN	Q8MRC9, GALT9_DROME	Q9HCQ5, GALT9_HUMAN
Q9GM01, GALT9_MACFA	S5S833, GALT_BIOGL	A8Y236, GLT10_CAEBR
O45947, GLT10_CAEEL	Q8IA43, GLT10_DROME	Q86SR1, GLT10_HUMAN
Q6P9S7, GLT10_MOUSE	Q925R7, GLT10_RAT	Q7K755, GLT11_CAEEL
Q8NCW6, GLT11_HUMAN	Q921L8, GLT11_MOUSE	Q6P6V1, GLT11_RAT
Q6DJR8, GLT11_XENTR	Q8IXK2, GLT12_HUMAN	Q8BGT9, GLT12_MOUSE
Q8MYY6, GLT13_DROME	Q8IUC8, GLT13_HUMAN	Q8CF93, GLT13_MOUSE
Q6UE39, GLT13_RAT	Q96FL9, GLT14_HUMAN	Q8BVG5, GLT14_MOUSE
Q8N3T1, GLT15_HUMAN	Q9D2N8, GLT15_MOUSE	Q8N428, GLT16_HUMAN
Q9JJ61, GLT16_MOUSE	Q6IS24, GLT17_HUMAN	Q7TT15, GLT17_MOUSE
Q6P9A2, GLT18_HUMAN	Q8K1B9, GLT18_MOUSE	Q8MVS5, GLT35_DROME
Q49A17, GLTL6_HUMAN

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.1.-
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