diff --git a/setup.py b/setup.py
index 6e1f732c..0224339e 100755
--- a/setup.py
+++ b/setup.py
@@ -16,6 +16,7 @@
     description="Pure Python MySQL Driver",
     long_description=readme,
     packages=find_packages(exclude=["tests*", "pymysql.tests*"]),
+    python_requires=">=3.6",
     extras_require={
         "rsa": ["cryptography"],
         "ed25519": ["PyNaCl>=1.4.0"],