RustPython
diff --git a/‎Lib/ensurepip/__init__.py
+18-9 b/‎Lib/ensurepip/__init__.py
+18-9
diff --git a/‎Lib/ensurepip/_bundled/__init__.py b/‎Lib/ensurepip/_bundled/__init__.py
diff --git a/‎Lib/ensurepip/_bundled/pip-22.0.4-py3-none-any.whl
-2.03 MB b/‎Lib/ensurepip/_bundled/pip-22.0.4-py3-none-any.whl
-2.03 MB
diff --git a/‎Lib/ensurepip/_bundled/pip-22.3.1-py3-none-any.whl
1.96 MB b/‎Lib/ensurepip/_bundled/pip-22.3.1-py3-none-any.whl
1.96 MB
diff --git a/‎Lib/ensurepip/_bundled/setuptools-58.1.0-py3-none-any.whl
-798 KB b/‎Lib/ensurepip/_bundled/setuptools-58.1.0-py3-none-any.whl
-798 KB
diff --git a/‎Lib/ensurepip/_bundled/setuptools-65.5.0-py3-none-any.whl
1.18 MB b/‎Lib/ensurepip/_bundled/setuptools-65.5.0-py3-none-any.whl
1.18 MB
@@ -8,11 +8,10 @@
 from importlib import resources
 
 
-
 __all__ = ["version", "bootstrap"]
 _PACKAGE_NAMES = ('setuptools', 'pip')
-_SETUPTOOLS_VERSION = "58.1.0"
-_PIP_VERSION = "22.0.4"
+_SETUPTOOLS_VERSION = "65.5.0"
+_PIP_VERSION = "22.3.1"
 _PROJECTS = [
     ("setuptools", _SETUPTOOLS_VERSION, "py3"),
     ("pip", _PIP_VERSION, "py3"),
@@ -79,8 +78,8 @@ def _get_packages():
 
 
 def _run_pip(args, additional_paths=None):
-    # Run the bootstraping in a subprocess to avoid leaking any state that happens
-    # after pip has executed. Particulary, this avoids the case when pip holds onto
+    # Run the bootstrapping in a subprocess to avoid leaking any state that happens
+    # after pip has executed. Particularly, this avoids the case when pip holds onto
     # the files in *additional_paths*, preventing us to remove them at the end of the
     # invocation.
     code = f"""
@@ -90,8 +89,18 @@ def _run_pip(args, additional_paths=None):
 sys.argv[1:] = {args}
 runpy.run_module("pip", run_name="__main__", alter_sys=True)
 """
-    return subprocess.run([sys.executable, '-W', 'ignore::DeprecationWarning',
-                           "-c", code], check=True).returncode
+
+    cmd = [
+        sys.executable,
+        '-W',
+        'ignore::DeprecationWarning',
+        '-c',
+        code,
+    ]
+    if sys.flags.isolated:
+        # run code in isolated mode if currently running isolated
+        cmd.insert(1, '-I')
+    return subprocess.run(cmd, check=True).returncode
 
 
 def version():
@@ -164,9 +173,9 @@ def _bootstrap(*, root=None, upgrade=False, user=False,
         for name, package in _get_packages().items():
             if package.wheel_name:
                 # Use bundled wheel package
-                from ensurepip import _bundled
                 wheel_name = package.wheel_name
-                whl = resources.read_binary(_bundled, wheel_name)
+                wheel_path = resources.files("ensurepip") / "_bundled" / wheel_name
+                whl = wheel_path.read_bytes()
             else:
                 # Use the wheel package directory
                 with open(package.wheel_path, "rb") as fp: