diff --git a/CHANGELOG.md b/CHANGELOG.md
index 7ed6c616..c84458ba 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -4,6 +4,14 @@
 
 [1]: https://pypi.org/project/google-api-core/#history
 
+### [2.8.1](https://github.com/googleapis/python-api-core/compare/v2.8.0...v2.8.1) (2022-05-26)
+
+
+### Bug Fixes
+
+* **deps:** require googleapis-common-protos >= 1.56.2 ([d84d66c](https://github.com/googleapis/python-api-core/commit/d84d66c2a4107f5f9a20c53e870a27fb1250ea3d))
+* **deps:** require protobuf>= 3.15.0, <4.0.0dev ([#385](https://github.com/googleapis/python-api-core/issues/385)) ([d84d66c](https://github.com/googleapis/python-api-core/commit/d84d66c2a4107f5f9a20c53e870a27fb1250ea3d))
+
 ## [2.8.0](https://github.com/googleapis/python-api-core/compare/v2.7.3...v2.8.0) (2022-05-18)
 
 
diff --git a/google/api_core/version.py b/google/api_core/version.py
index 0a9aecb3..7e8f51a6 100644
--- a/google/api_core/version.py
+++ b/google/api_core/version.py
@@ -12,4 +12,4 @@
 # See the License for the specific language governing permissions and
 # limitations under the License.
 
-__version__ = "2.8.0"
+__version__ = "2.8.1"
diff --git a/setup.py b/setup.py
index e400a52f..70b26c92 100644
--- a/setup.py
+++ b/setup.py
@@ -29,15 +29,15 @@
 # 'Development Status :: 5 - Production/Stable'
 release_status = "Development Status :: 5 - Production/Stable"
 dependencies = [
-    "googleapis-common-protos >= 1.52.0, < 2.0dev",
-    "protobuf >= 3.12.0",
+    "googleapis-common-protos >= 1.56.2, < 2.0dev",
+    "protobuf >= 3.15.0, <4.0.0dev",
     "google-auth >= 1.25.0, < 3.0dev",
     "requests >= 2.18.0, < 3.0.0dev",
 ]
 extras = {
     "grpc": ["grpcio >= 1.33.2, < 2.0dev", "grpcio-status >= 1.33.2, < 2.0dev"],
-    "grpcgcp": "grpcio-gcp >= 0.2.2",
-    "grpcio-gcp": "grpcio-gcp >= 0.2.2",
+    "grpcgcp": "grpcio-gcp >= 0.2.2, < 1.0dev",
+    "grpcio-gcp": "grpcio-gcp >= 0.2.2, < 1.0dev",
 }
 
 
diff --git a/testing/constraints-3.6.txt b/testing/constraints-3.6.txt
index bb1eb1e3..014e2b2a 100644
--- a/testing/constraints-3.6.txt
+++ b/testing/constraints-3.6.txt
@@ -5,8 +5,8 @@
 #
 # e.g., if setup.py has "foo >= 1.14.0, < 2.0.0dev",
 # Then this file should have foo==1.14.0
-googleapis-common-protos==1.52.0
-protobuf==3.12.0
+googleapis-common-protos==1.56.2
+protobuf==3.15.0
 google-auth==1.25.0
 requests==2.18.0
 packaging==14.3