def example_plot(ax, fontsize=12, hide_labels=False):
    pc = ax.pcolormesh(np.random.randn(30, 30), vmin=-2.5, vmax=2.5)
    if not hide_labels:
        ax.set_xlabel('x-label', fontsize=fontsize)
        ax.set_ylabel('y-label', fontsize=fontsize)
        ax.set_title('Title', fontsize=fontsize)
    return pc

np.random.seed(19680808)
# gridspec inside gridspec
fig = plt.figure(constrained_layout=True, figsize=(10, 4))
subfigs = fig.subfigures(1, 2, wspace=0.07)

axsLeft = subfigs[0].subplots(1, 2, sharey=True)
subfigs[0].set_facecolor('0.75')
for ax in axsLeft:
    pc = example_plot(ax)
subfigs[0].suptitle('Left plots', fontsize='x-large')
subfigs[0].colorbar(pc, shrink=0.6, ax=axsLeft, location='bottom')

axsRight = subfigs[1].subplots(3, 1, sharex=True)
for nn, ax in enumerate(axsRight):
    pc = example_plot(ax, hide_labels=True)
    if nn == 2:
        ax.set_xlabel('xlabel')
    if nn == 1:
        ax.set_ylabel('ylabel')

subfigs[1].set_facecolor('0.85')
subfigs[1].colorbar(pc, shrink=0.6, ax=axsRight)
subfigs[1].suptitle('Right plots', fontsize='x-large')

# fig.suptitle('Figure suptitle', fontsize='xx-large')
plt.show()