diff --git a/lib/matplotlib/axes/_base.py b/lib/matplotlib/axes/_base.py
index 181293b7983c..4b89640ffcc5 100644
--- a/lib/matplotlib/axes/_base.py
+++ b/lib/matplotlib/axes/_base.py
@@ -542,17 +542,25 @@ def __getstate__(self):
         # The renderer should be re-created by the figure, and then cached at
         # that point.
         state = super().__getstate__()
-        state['_cachedRenderer'] = None
-        state.pop('_layoutbox')
-        state.pop('_poslayoutbox')
-
+        for key in ['_cachedRenderer', '_layoutbox', '_poslayoutbox']:
+            state[key] = None
+        # Prune the sharing & twinning info to only contain the current group.
+        for grouper_name in [
+                '_shared_x_axes', '_shared_y_axes', '_twinned_axes']:
+            grouper = getattr(self, grouper_name)
+            state[grouper_name] = (grouper.get_siblings(self)
+                                   if self in grouper else None)
         return state
 
     def __setstate__(self, state):
+        # Merge the grouping info back into the global groupers.
+        for grouper_name in [
+                '_shared_x_axes', '_shared_y_axes', '_twinned_axes']:
+            siblings = state.pop(grouper_name)
+            if siblings:
+                getattr(self, grouper_name).join(*siblings)
         self.__dict__ = state
         self._stale = True
-        self._layoutbox = None
-        self._poslayoutbox = None
 
     def get_window_extent(self, *args, **kwargs):
         """
diff --git a/lib/matplotlib/tests/test_pickle.py b/lib/matplotlib/tests/test_pickle.py
index 719dc7356fc8..1ba2e097181e 100644
--- a/lib/matplotlib/tests/test_pickle.py
+++ b/lib/matplotlib/tests/test_pickle.py
@@ -185,3 +185,10 @@ def test_rrulewrapper():
     except RecursionError:
         print('rrulewrapper pickling test failed')
         raise
+
+
+def test_shared():
+    fig, axs = plt.subplots(2, sharex=True)
+    fig = pickle.loads(pickle.dumps(fig))
+    fig.axes[0].set_xlim(10, 20)
+    assert fig.axes[1].get_xlim() == (10, 20)