diff --git a/lib/matplotlib/animation.py b/lib/matplotlib/animation.py
index f6376ed9c051..4cdd42469f88 100644
--- a/lib/matplotlib/animation.py
+++ b/lib/matplotlib/animation.py
@@ -1222,6 +1222,11 @@ def _setup_blit(self):
         # axes
         self._blit_cache = dict()
         self._drawn_artists = []
+        for ax in self._fig.axes:
+            ax.callbacks.connect('xlim_changed',
+                                 lambda ax: self._blit_cache.pop(ax, None))
+            ax.callbacks.connect('ylim_changed',
+                                 lambda ax: self._blit_cache.pop(ax, None))
         self._resize_id = self._fig.canvas.mpl_connect('resize_event',
                                                        self._handle_resize)
         self._post_draw(None, self._blit)