diff --git a/Lib/test/test_monitoring.py b/Lib/test/test_monitoring.py
index 2fd822036bcff5..2e17403fc45dd0 100644
--- a/Lib/test/test_monitoring.py
+++ b/Lib/test/test_monitoring.py
@@ -1801,6 +1801,21 @@ def test_gh108976(self):
         sys.monitoring.set_events(0, E.LINE | E.INSTRUCTION)
         sys.monitoring.set_events(0, 0)
 
+    def test_call_function_ex(self):
+        def f(a, b):
+            return a + b
+        args = (1, 2)
+
+        call_data = []
+        sys.monitoring.use_tool_id(0, "test")
+        self.addCleanup(sys.monitoring.free_tool_id, 0)
+        sys.monitoring.set_events(0, 0)
+        sys.monitoring.register_callback(0, E.CALL, lambda code, offset, callable, arg0: call_data.append((callable, arg0)))
+        sys.monitoring.set_events(0, E.CALL)
+        f(*args)
+        sys.monitoring.set_events(0, 0)
+        self.assertEqual(call_data[0], (f, 1))
+
 
 class TestOptimizer(MonitoringTestBase, unittest.TestCase):
 
diff --git a/Misc/NEWS.d/next/Core and Builtins/2024-03-11-22-05-56.gh-issue-116626.GsyczB.rst b/Misc/NEWS.d/next/Core and Builtins/2024-03-11-22-05-56.gh-issue-116626.GsyczB.rst
new file mode 100644
index 00000000000000..5b18d04cca64b5
--- /dev/null
+++ b/Misc/NEWS.d/next/Core and Builtins/2024-03-11-22-05-56.gh-issue-116626.GsyczB.rst	
@@ -0,0 +1 @@
+Ensure ``INSTRUMENTED_CALL_FUNCTION_EX`` always emits :monitoring-event:`CALL`
diff --git a/Python/bytecodes.c b/Python/bytecodes.c
index 1d515098f6c7e9..753fe9ab049070 100644
--- a/Python/bytecodes.c
+++ b/Python/bytecodes.c
@@ -3695,9 +3695,7 @@ dummy_func(
             }
             assert(PyTuple_CheckExact(callargs));
             EVAL_CALL_STAT_INC_IF_FUNCTION(EVAL_CALL_FUNCTION_EX, func);
-            if (opcode == INSTRUMENTED_CALL_FUNCTION_EX &&
-                !PyFunction_Check(func) && !PyMethod_Check(func)
-            ) {
+            if (opcode == INSTRUMENTED_CALL_FUNCTION_EX) {
                 PyObject *arg = PyTuple_GET_SIZE(callargs) > 0 ?
                     PyTuple_GET_ITEM(callargs, 0) : Py_None;
                 int err = _Py_call_instrumentation_2args(
@@ -3705,17 +3703,20 @@ dummy_func(
                     frame, this_instr, func, arg);
                 if (err) GOTO_ERROR(error);
                 result = PyObject_Call(func, callargs, kwargs);
-                if (result == NULL) {
-                    _Py_call_instrumentation_exc2(
-                        tstate, PY_MONITORING_EVENT_C_RAISE,
-                        frame, this_instr, func, arg);
-                }
-                else {
-                    int err = _Py_call_instrumentation_2args(
-                        tstate, PY_MONITORING_EVENT_C_RETURN,
-                        frame, this_instr, func, arg);
-                    if (err < 0) {
-                        Py_CLEAR(result);
+
+                if (!PyFunction_Check(func) && !PyMethod_Check(func)) {
+                    if (result == NULL) {
+                        _Py_call_instrumentation_exc2(
+                            tstate, PY_MONITORING_EVENT_C_RAISE,
+                            frame, this_instr, func, arg);
+                    }
+                    else {
+                        int err = _Py_call_instrumentation_2args(
+                            tstate, PY_MONITORING_EVENT_C_RETURN,
+                            frame, this_instr, func, arg);
+                        if (err < 0) {
+                            Py_CLEAR(result);
+                        }
                     }
                 }
             }
diff --git a/Python/generated_cases.c.h b/Python/generated_cases.c.h
index 3312078e9a2d4d..65ca36d7f6bc77 100644
--- a/Python/generated_cases.c.h
+++ b/Python/generated_cases.c.h
@@ -1198,9 +1198,7 @@
             }
             assert(PyTuple_CheckExact(callargs));
             EVAL_CALL_STAT_INC_IF_FUNCTION(EVAL_CALL_FUNCTION_EX, func);
-            if (opcode == INSTRUMENTED_CALL_FUNCTION_EX &&
-                !PyFunction_Check(func) && !PyMethod_Check(func)
-            ) {
+            if (opcode == INSTRUMENTED_CALL_FUNCTION_EX) {
                 PyObject *arg = PyTuple_GET_SIZE(callargs) > 0 ?
                 PyTuple_GET_ITEM(callargs, 0) : Py_None;
                 int err = _Py_call_instrumentation_2args(
@@ -1208,17 +1206,19 @@
                     frame, this_instr, func, arg);
                 if (err) GOTO_ERROR(error);
                 result = PyObject_Call(func, callargs, kwargs);
-                if (result == NULL) {
-                    _Py_call_instrumentation_exc2(
-                        tstate, PY_MONITORING_EVENT_C_RAISE,
-                        frame, this_instr, func, arg);
-                }
-                else {
-                    int err = _Py_call_instrumentation_2args(
-                        tstate, PY_MONITORING_EVENT_C_RETURN,
-                        frame, this_instr, func, arg);
-                    if (err < 0) {
-                        Py_CLEAR(result);
+                if (!PyFunction_Check(func) && !PyMethod_Check(func)) {
+                    if (result == NULL) {
+                        _Py_call_instrumentation_exc2(
+                            tstate, PY_MONITORING_EVENT_C_RAISE,
+                            frame, this_instr, func, arg);
+                    }
+                    else {
+                        int err = _Py_call_instrumentation_2args(
+                            tstate, PY_MONITORING_EVENT_C_RETURN,
+                            frame, this_instr, func, arg);
+                        if (err < 0) {
+                            Py_CLEAR(result);
+                        }
                     }
                 }
             }