diff --git a/Doc/c-api/stable.rst b/Doc/c-api/stable.rst
index 124e58cf950b7a..25727d9a550ea1 100644
--- a/Doc/c-api/stable.rst
+++ b/Doc/c-api/stable.rst
@@ -113,7 +113,8 @@ On Windows, extensions that use the Stable ABI should be linked against
 ``python39.dll``.
 
 On some platforms, Python will look for and load shared library files named
-with the ``abi3`` tag (e.g. ``mymodule.abi3.so``).
+with the ``abi3`` tag (e.g. ``mymodule.abi3.so`` or
+``mymodule.abi3-x86-64-linux-gnu.so``).
 It does not check if such extensions conform to a Stable ABI.
 The user (or their packaging tools) need to ensure that, for example,
 extensions built with the 3.10+ Limited API are not installed for lower
diff --git a/Doc/whatsnew/3.14.rst b/Doc/whatsnew/3.14.rst
index a561d3b3383fc5..6f07d51ac80b8d 100644
--- a/Doc/whatsnew/3.14.rst
+++ b/Doc/whatsnew/3.14.rst
@@ -455,6 +455,15 @@ Other language changes
   The testbed can also be used to run the test suite of projects other than
   CPython itself. (Contributed by Russell Keith-Magee in :gh:`127592`.)
 
+* Stable ABI extensions may now include a multiarch tuple in the
+  filename, e.g. ``foo.abi3-x86-64-linux-gnu.so``.
+  This permits stable ABI extensions for multiple architectures to be
+  co-installed into the same directory, without clashing with each
+  other, as regular dynamic extensions do. Build tools will not generate
+  these multiarch tagged filenames, by default, while still supporting
+  older Python versions that don't recognize these filenames.
+  (Contributed by Stefano Rivera in :gh:`122931`.)
+
 .. _whatsnew314-pep765:
 
 PEP 765: Disallow return/break/continue that exit a finally block
diff --git a/Makefile.pre.in b/Makefile.pre.in
index 3ef0c6320c85db..5d5fe2f9448199 100644
--- a/Makefile.pre.in
+++ b/Makefile.pre.in
@@ -1817,6 +1817,7 @@ Python/interpconfig.o: $(srcdir)/Python/interpconfig.c $(srcdir)/Python/config_c
 Python/dynload_shlib.o: $(srcdir)/Python/dynload_shlib.c Makefile
 	$(CC) -c $(PY_CORE_CFLAGS) \
 		-DSOABI='"$(SOABI)"' \
+		$(MULTIARCH_CPPFLAGS) \
 		-o $@ $(srcdir)/Python/dynload_shlib.c
 
 Python/dynload_hpux.o: $(srcdir)/Python/dynload_hpux.c Makefile
diff --git a/Misc/NEWS.d/next/C_API/2024-08-12-09-48-04.gh-issue-122931.QwHc2l.rst b/Misc/NEWS.d/next/C_API/2024-08-12-09-48-04.gh-issue-122931.QwHc2l.rst
new file mode 100644
index 00000000000000..d1caad2e98482d
--- /dev/null
+++ b/Misc/NEWS.d/next/C_API/2024-08-12-09-48-04.gh-issue-122931.QwHc2l.rst
@@ -0,0 +1,2 @@
+Allow importing stable ABI C extensions that include a multiarch tuple
+in their filename, e.g. ``foo.abi3-x86-64-linux-gnu.so``.
diff --git a/Python/dynload_shlib.c b/Python/dynload_shlib.c
index 583c9b752dfd90..cc42818da04422 100644
--- a/Python/dynload_shlib.c
+++ b/Python/dynload_shlib.c
@@ -45,6 +45,9 @@ const char *_PyImport_DynLoadFiletab[] = {
     "." ALT_SOABI ".so",
 #endif
     ".abi" PYTHON_ABI_STRING ".so",
+#ifdef MULTIARCH
+    ".abi" PYTHON_ABI_STRING "-" MULTIARCH ".so",
+#endif
     ".so",
 #endif  /* __CYGWIN__ */
     NULL,