diff --git a/README.rst b/README.rst
index 84bf93d84..ee6573d84 100644
--- a/README.rst
+++ b/README.rst
@@ -95,6 +95,14 @@ projects using pythonnet can be found in the Wiki:
 
 https://github.com/pythonnet/pythonnet/wiki
 
+Python 3.8.0 support
+--------------------
+
+Some features are disabled in Python 3.8.0 because of
+`this bug in Python <https://bugs.python.org/issue37633>`_. The error is
+``System.EntryPointNotFoundException : Unable to find an entry point named
+'Py_CompileString' in DLL 'python38'``. This will be fixed in Python 3.8.1.
+
 .. |Join the chat at https://gitter.im/pythonnet/pythonnet| image:: https://badges.gitter.im/pythonnet/pythonnet.svg
    :target: https://gitter.im/pythonnet/pythonnet?utm_source=badge&utm_medium=badge&utm_campaign=pr-badge&utm_content=badge
 .. |appveyor shield| image:: https://img.shields.io/appveyor/ci/pythonnet/pythonnet/master.svg?label=AppVeyor
diff --git a/appveyor.yml b/appveyor.yml
index 445f9bb5a..20d8ed991 100644
--- a/appveyor.yml
+++ b/appveyor.yml
@@ -23,16 +23,22 @@ environment:
       BUILD_OPTS: --xplat
     - PYTHON_VERSION: 3.7
       BUILD_OPTS: --xplat
+    - PYTHON_VERSION: 3.8
+      BUILD_OPTS: --xplat
     - PYTHON_VERSION: 2.7
     - PYTHON_VERSION: 3.5
     - PYTHON_VERSION: 3.6
     - PYTHON_VERSION: 3.7
+    - PYTHON_VERSION: 3.8
 
 matrix:
     allow_failures:
       - PYTHON_VERSION: 3.4
         BUILD_OPTS: --xplat
       - PYTHON_VERSION: 3.4
+      - PYTHON_VERSION: 3.8
+        BUILD_OPTS: --xplat
+      - PYTHON_VERSION: 3.8
 
 init:
   # Update Environment Variables based on matrix/platform
diff --git a/src/runtime/Python.Runtime.15.csproj b/src/runtime/Python.Runtime.15.csproj
index 122132513..c31d4bf91 100644
--- a/src/runtime/Python.Runtime.15.csproj
+++ b/src/runtime/Python.Runtime.15.csproj
@@ -42,7 +42,7 @@
     <Python2Version>$(PYTHONNET_PY2_VERSION)</Python2Version>
     <Python2Version Condition="'$(Python2Version)'==''">PYTHON27</Python2Version>
     <Python3Version>$(PYTHONNET_PY3_VERSION)</Python3Version>
-    <Python3Version Condition="'$(Python3Version)'==''">PYTHON37</Python3Version>
+    <Python3Version Condition="'$(Python3Version)'==''">PYTHON38</Python3Version>
     <PythonWinDefineConstants>$(PYTHONNET_WIN_DEFINE_CONSTANTS)</PythonWinDefineConstants>
     <PythonWinDefineConstants Condition="'$(PythonWinDefineConstants)'==''">UCS2</PythonWinDefineConstants>
     <PythonMonoDefineConstants>$(PYTHONNET_MONO_DEFINE_CONSTANTS)</PythonMonoDefineConstants>
diff --git a/src/runtime/Python.Runtime.csproj b/src/runtime/Python.Runtime.csproj
index ac6b59150..02656e51e 100644
--- a/src/runtime/Python.Runtime.csproj
+++ b/src/runtime/Python.Runtime.csproj
@@ -22,11 +22,11 @@
   </PropertyGroup>
   <!--We can relax binding to platform because code references no any platform dependent assemblies-->
   <!--This will allows to use any build of this assebly as a compile ref assebly-->
-  <!--<PropertyGroup Condition=" '$(Platform)' == 'x86'">
-    <PlatformTarget>x86</PlatformTarget>
-  </PropertyGroup>
-  <PropertyGroup Condition=" '$(Platform)' == 'x64'">
-    <PlatformTarget>x64</PlatformTarget>
+  <!--<PropertyGroup Condition=" '$(Platform)' == 'x86'">
+    <PlatformTarget>x86</PlatformTarget>
+  </PropertyGroup>
+  <PropertyGroup Condition=" '$(Platform)' == 'x64'">
+    <PlatformTarget>x64</PlatformTarget>
   </PropertyGroup>-->
   <PropertyGroup Condition=" '$(Configuration)' == 'ReleaseMono'">
     <DefineConstants Condition="'$(DefineConstants)' == ''">PYTHON2;PYTHON27;UCS4</DefineConstants>
@@ -34,7 +34,7 @@
     <DebugType>pdbonly</DebugType>
   </PropertyGroup>
   <PropertyGroup Condition=" '$(Configuration)' == 'ReleaseMonoPY3'">
-    <DefineConstants Condition="'$(DefineConstants)' == ''">PYTHON3;PYTHON37;UCS4</DefineConstants>
+    <DefineConstants Condition="'$(DefineConstants)' == ''">PYTHON3;PYTHON38;UCS4</DefineConstants>
     <Optimize>true</Optimize>
     <DebugType>pdbonly</DebugType>
   </PropertyGroup>
@@ -46,7 +46,7 @@
   </PropertyGroup>
   <PropertyGroup Condition=" '$(Configuration)' == 'DebugMonoPY3'">
     <DebugSymbols>true</DebugSymbols>
-    <DefineConstants Condition="'$(DefineConstants)' == ''">PYTHON3;PYTHON37;UCS4;TRACE;DEBUG</DefineConstants>
+    <DefineConstants Condition="'$(DefineConstants)' == ''">PYTHON3;PYTHON38;UCS4;TRACE;DEBUG</DefineConstants>
     <Optimize>false</Optimize>
     <DebugType>full</DebugType>
   </PropertyGroup>
@@ -56,7 +56,7 @@
     <DebugType>pdbonly</DebugType>
   </PropertyGroup>
   <PropertyGroup Condition=" '$(Configuration)' == 'ReleaseWinPY3'">
-    <DefineConstants Condition="'$(DefineConstants)' == ''">PYTHON3;PYTHON37;UCS2</DefineConstants>
+    <DefineConstants Condition="'$(DefineConstants)' == ''">PYTHON3;PYTHON38;UCS2</DefineConstants>
     <Optimize>true</Optimize>
     <DebugType>pdbonly</DebugType>
   </PropertyGroup>
@@ -68,7 +68,7 @@
   </PropertyGroup>
   <PropertyGroup Condition=" '$(Configuration)' == 'DebugWinPY3'">
     <DebugSymbols>true</DebugSymbols>
-    <DefineConstants Condition="'$(DefineConstants)' == ''">PYTHON3;PYTHON37;UCS2;TRACE;DEBUG</DefineConstants>
+    <DefineConstants Condition="'$(DefineConstants)' == ''">PYTHON3;PYTHON38;UCS2;TRACE;DEBUG</DefineConstants>
     <Optimize>false</Optimize>
     <DebugType>full</DebugType>
   </PropertyGroup>
@@ -140,8 +140,8 @@
     <Compile Include="typemanager.cs" />
     <Compile Include="typemethod.cs" />
     <Compile Include="Util.cs" />
-    <Compile Include="platform\Types.cs" />
-    <Compile Include="platform\LibraryLoader.cs" />
+    <Compile Include="platform\Types.cs" />
+    <Compile Include="platform\LibraryLoader.cs" />
   </ItemGroup>
   <ItemGroup Condition=" '$(PythonInteropFile)' != '' ">
     <Compile Include="$(PythonInteropFile)" />
@@ -151,7 +151,8 @@
     <Compile Include="interop34.cs" />
     <Compile Include="interop35.cs" />
     <Compile Include="interop36.cs" />
-    <Compile Include="interop37.cs" />
+    <Compile Include="interop37.cs" />
+    <Compile Include="interop38.cs" />
   </ItemGroup>
   <ItemGroup>
     <None Include="..\pythonnet.snk" />
@@ -170,4 +171,4 @@
     <Copy SourceFiles="$(TargetAssembly)" DestinationFolder="$(PythonBuildDir)" />
     <!--Copy SourceFiles="$(TargetAssemblyPdb)" Condition="Exists('$(TargetAssemblyPdb)')" DestinationFolder="$(PythonBuildDir)" /-->
   </Target>
-</Project>
+</Project>
diff --git a/src/runtime/interop38.cs b/src/runtime/interop38.cs
new file mode 100644
index 000000000..8f2e32afe
--- /dev/null
+++ b/src/runtime/interop38.cs
@@ -0,0 +1,152 @@
+
+// Auto-generated by geninterop.py.
+// DO NOT MODIFIY BY HAND.
+
+
+#if PYTHON38
+using System;
+using System.Collections;
+using System.Collections.Specialized;
+using System.Runtime.InteropServices;
+using System.Reflection;
+using System.Text;
+
+namespace Python.Runtime
+{
+    [StructLayout(LayoutKind.Sequential, CharSet = CharSet.Ansi)]
+    internal class TypeOffset
+    {
+        static TypeOffset()
+        {
+            Type type = typeof(TypeOffset);
+            FieldInfo[] fi = type.GetFields();
+            int size = IntPtr.Size;
+            for (int i = 0; i < fi.Length; i++)
+            {
+                fi[i].SetValue(null, i * size);
+            }
+        }
+
+        public static int magic()
+        {
+            return ob_size;
+        }
+
+        // Auto-generated from PyHeapTypeObject in Python.h
+        public static int ob_refcnt = 0;
+        public static int ob_type = 0;
+        public static int ob_size = 0;
+        public static int tp_name = 0;
+        public static int tp_basicsize = 0;
+        public static int tp_itemsize = 0;
+        public static int tp_dealloc = 0;
+        public static int tp_vectorcall_offset = 0;
+        public static int tp_getattr = 0;
+        public static int tp_setattr = 0;
+        public static int tp_as_async = 0;
+        public static int tp_repr = 0;
+        public static int tp_as_number = 0;
+        public static int tp_as_sequence = 0;
+        public static int tp_as_mapping = 0;
+        public static int tp_hash = 0;
+        public static int tp_call = 0;
+        public static int tp_str = 0;
+        public static int tp_getattro = 0;
+        public static int tp_setattro = 0;
+        public static int tp_as_buffer = 0;
+        public static int tp_flags = 0;
+        public static int tp_doc = 0;
+        public static int tp_traverse = 0;
+        public static int tp_clear = 0;
+        public static int tp_richcompare = 0;
+        public static int tp_weaklistoffset = 0;
+        public static int tp_iter = 0;
+        public static int tp_iternext = 0;
+        public static int tp_methods = 0;
+        public static int tp_members = 0;
+        public static int tp_getset = 0;
+        public static int tp_base = 0;
+        public static int tp_dict = 0;
+        public static int tp_descr_get = 0;
+        public static int tp_descr_set = 0;
+        public static int tp_dictoffset = 0;
+        public static int tp_init = 0;
+        public static int tp_alloc = 0;
+        public static int tp_new = 0;
+        public static int tp_free = 0;
+        public static int tp_is_gc = 0;
+        public static int tp_bases = 0;
+        public static int tp_mro = 0;
+        public static int tp_cache = 0;
+        public static int tp_subclasses = 0;
+        public static int tp_weaklist = 0;
+        public static int tp_del = 0;
+        public static int tp_version_tag = 0;
+        public static int tp_finalize = 0;
+        public static int tp_vectorcall = 0;
+        public static int am_await = 0;
+        public static int am_aiter = 0;
+        public static int am_anext = 0;
+        public static int nb_add = 0;
+        public static int nb_subtract = 0;
+        public static int nb_multiply = 0;
+        public static int nb_remainder = 0;
+        public static int nb_divmod = 0;
+        public static int nb_power = 0;
+        public static int nb_negative = 0;
+        public static int nb_positive = 0;
+        public static int nb_absolute = 0;
+        public static int nb_bool = 0;
+        public static int nb_invert = 0;
+        public static int nb_lshift = 0;
+        public static int nb_rshift = 0;
+        public static int nb_and = 0;
+        public static int nb_xor = 0;
+        public static int nb_or = 0;
+        public static int nb_int = 0;
+        public static int nb_reserved = 0;
+        public static int nb_float = 0;
+        public static int nb_inplace_add = 0;
+        public static int nb_inplace_subtract = 0;
+        public static int nb_inplace_multiply = 0;
+        public static int nb_inplace_remainder = 0;
+        public static int nb_inplace_power = 0;
+        public static int nb_inplace_lshift = 0;
+        public static int nb_inplace_rshift = 0;
+        public static int nb_inplace_and = 0;
+        public static int nb_inplace_xor = 0;
+        public static int nb_inplace_or = 0;
+        public static int nb_floor_divide = 0;
+        public static int nb_true_divide = 0;
+        public static int nb_inplace_floor_divide = 0;
+        public static int nb_inplace_true_divide = 0;
+        public static int nb_index = 0;
+        public static int nb_matrix_multiply = 0;
+        public static int nb_inplace_matrix_multiply = 0;
+        public static int mp_length = 0;
+        public static int mp_subscript = 0;
+        public static int mp_ass_subscript = 0;
+        public static int sq_length = 0;
+        public static int sq_concat = 0;
+        public static int sq_repeat = 0;
+        public static int sq_item = 0;
+        public static int was_sq_slice = 0;
+        public static int sq_ass_item = 0;
+        public static int was_sq_ass_slice = 0;
+        public static int sq_contains = 0;
+        public static int sq_inplace_concat = 0;
+        public static int sq_inplace_repeat = 0;
+        public static int bf_getbuffer = 0;
+        public static int bf_releasebuffer = 0;
+        public static int name = 0;
+        public static int ht_slots = 0;
+        public static int qualname = 0;
+        public static int ht_cached_keys = 0;
+
+        /* here are optional user slots, followed by the members. */
+        public static int members = 0;
+    }
+}
+
+#endif
+
diff --git a/src/runtime/runtime.cs b/src/runtime/runtime.cs
index f97821d13..7a78cd6e1 100644
--- a/src/runtime/runtime.cs
+++ b/src/runtime/runtime.cs
@@ -64,8 +64,11 @@ public class Runtime
 #elif PYTHON37
         internal const string _pyversion = "3.7";
         internal const string _pyver = "37";
+#elif PYTHON38
+        internal const string _pyversion = "3.8";
+        internal const string _pyver = "38";
 #else
-#error You must define one of PYTHON34 to PYTHON37 or PYTHON27
+#error You must define one of PYTHON34 to PYTHON38 or PYTHON27
 #endif
 
 #if MONO_LINUX || MONO_OSX // Linux/macOS use dotted version string