Mast cell disorder

Known for their role in allergic reactions, mast cells have long been recognized as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy symptoms such as tissue swelling and inflammation.

Mast Cell

Part 1 1. What are mast cells? 2. What is mast cell disease? Part 2 3. What causes mast cell disease? 4. Is mast cell disease heritable? 5. Can mast cell disease be cured? Part 3 6. What symptoms does mast cell disease cause? 7. Why are skin and GI symptoms so common? Part 4… Read More »The MastAttack 107: The Layperson’s Guide to Understanding Mast Cell Diseases

What is Mast Cell Activation Syndrome? “Traditionally, Mast Cell Activation Syndrome (MCAS) was considered a rare disease generally focusing on the mast cell mediators tryptase and histamine and the blatant symptoms of flushing and anaphylaxis. New research indicates that it plays a large role in many chronic health conditions. Mast cells are coordinators of our […]

What is Mast Cell Activation Disorder, or MCAD? What does it look like? How do you find out if you have it? How do you treat it? I've mentioned MCAD (Mast C

Background Mounting evidence supports a mechanistic association between irritable bowel syndrome (IBS) symptoms and mast cell hyperactivity. Yet, association between IBS and mast cell disorders (MCD...

Systemic mastocytosis is a blood disorder characterized by infiltration of clonally derived mast cells in different tissues, including bone marrow, the gastrointestinal (GI) tract, the liver, and the spleen.

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This website is dedicated to helping newcomers and medical providers to navigate mastocytosis and mast cell activation syndrome.