Papers by Aliona Serbulenco
Catedra Igienă USMF „Nicolae Testemiţanu”, Centrul Naţional de Sănătate PublicăThe research consi... more Catedra Igienă USMF „Nicolae Testemiţanu”, Centrul Naţional de Sănătate PublicăThe research considers the results of implementation the screening for identification the biological, behavioural and social risk factors, which causes increased morbidity and mortality among people with cardiovascular diseases in Căuşeni district. The period of research - October 2012 - March 2013. As a research method was used in the evaluation questionnaire. According to the scale for determining cardiovascular risk - Heart SCORE was established the contribution of risk factors (systolic BP, parameters of cholesterol in the blood, smoking, obesity etc.) to the total individual risk. În cercetare sunt elucidate rezultatele de implementare a screening-ului populațional pentru identificarea factorilor de risc biologici, comportamentali, sociali, care determină morbiditatea și mortalitatea sporită a populației prin maladii cardiovasculare în raionul Căușeni. Perioada de desfășurare a cercetării – octombrie...
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Agenția Națională pentru Sănătate PublicăScopul lucrării este analiza acoperirii vaccinale la mal... more Agenția Națională pentru Sănătate PublicăScopul lucrării este analiza acoperirii vaccinale la maladiile țintă din Programul național de imunizări (PNI) conform formularelor de raportare și depistarea problemelor existente. În anii 2017-2018, comparativ cu perioada 2012-2016, s-a mărit numărul teritoriilor cu indicatori nesatisfăcători de acoperire vaccinală (<90-95%). Se observă modifi carea semnifi cativă a numărului total de copii în diferiți ani în toate grupele de vârstă analizate. Sunt modificări atât negative (anul nașterii 2002: la vârsta de 7 și 15 ani – respectiv 98,8% și 93,0% din numărul copiilor la vârsta de un an; anul nașterii 2003: la vârsta de 15 ani – 96,5%), cât și pozitive (anii nașterii 2003, 2007 și 2010: la 7 ani, respectiv 100,5%, 102,4% și 101,2%). Supravegherea cu utilizarea formularelor scrise nu permite depistarea și includerea modificărilor apărute în timp real. În condițiile de migrație intensivă a populației, este necesar de perfecționat modalitatea ...
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Вестник Академии Наук Молдовы. Медицина, 2011
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Вестник Академии Наук Молдовы. Медицина, 2017
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Общественное здоровье, экономика и менеджмент в медицине, 2019
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Общественное здравоохранение, экономика и менеджмент в медицине, 2018
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Multidrug-resistant tuberculosis (MDR-TB) is a major concern in countries of the former Soviet Un... more Multidrug-resistant tuberculosis (MDR-TB) is a major concern in countries of the former Soviet Union. The reported risk of resistance among TB cases in the Republic of Moldova is among the highest in the world. We aimed to produce high-resolution spatial maps of MDR-TB risk and burden in this setting. We analyzed national TB surveillance data collected between 2007 and 2010 in Moldova. High drug susceptibility testing coverage and detailed location data permitted identification of sub-regional areas of higher MDR-TB risk. We investigated whether the distribution of cases with MDR-TB risk factors could explain this observed spatial variation in MDR-TB. 3,447 MDR-TB cases were notified during this period; 24 % of new and 62 % of previously treated patients had MDR-TB. Nationally, the estimated annual MDR-TB incidence was 54 cases/100,000 persons and>1,000 cases/100,000 persons within penitentiaries. We identified substantial geographic variation in MDR-TB burden and hotspots of MDR...
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Model construction of individual level models We used logistic regression models to identify fact... more Model construction of individual level models We used logistic regression models to identify factors associated with multidrug-resistant tuberculosis (MDR-TB) at initial diagnosis. Several potentially explanatory variables were included in the full model and then removed used a backwards elimination method as follows. Variables were removed from the multivariable model sequentially by size of p-value for association with MDR-TB (beginning with the largest). As each variable was removed, the estimated parameters in the new model were compared with those in the model before removal. If removal of the variable altered any of the estimated parameters by at least 10%, then we retained that variable in the model to ensure appropriate adjustment. If the removed variable contained missing data, when comparing the parameter estimates for confounding, we ran the two models based on identical datasets (i.e. both excluding the missing data). The final models included all variables that were sta...
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European Respiratory Journal, 2012
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Papers by Aliona Serbulenco