Papers by Giovanna Marrazza
We report ontheinnovative electrical detection of biological binding, basedonathinmetaloxide (MOX... more We report ontheinnovative electrical detection of biological binding, basedonathinmetaloxide (MOX)filmas channel fora field effect transistor. Theworking principle relies onmodulation ofa MOX spacechargeregion (SCR) instead ofanenriched/depleted Sichannel like inchem-FETs. The feasibility of theworkingprinciple was at first demonstrated bypH measurement inliquid. Afterwards we implemented a reliable protocol fortheimmobilization of ODNsandfortheelectrical detection oftheir hybridization. Work isinprogress toscaleMOX down tonanosized nanowire.
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Sensors, 2019
Arsenic, one of the most abundant mineral and also one to the most toxic compounds. Due to its hi... more Arsenic, one of the most abundant mineral and also one to the most toxic compounds. Due to its high toxicity sensitive analytical methods are highly important, taking into account that the admitted level is in the range of µg L−1. A novel and easy to use platform for As(III) detection from water samples is proposed, based on gold and platinum bi metallic nanoparticles and a conductive polymer (polyaniline). The electrochemical detection was achieved after optimization of cathodic pre-concentration and stripping parameters by square wave anodic stripping voltammetry at modified screen-printed carbon-based electrochemical cells, proving its applicability for disposable and cost-effective in situ analysis of arsenic.
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Elsevier eBooks, 2005
1 SUMMARY Long life milk treated at ultra high temperature (UHT procedure) has been one of thesub... more 1 SUMMARY Long life milk treated at ultra high temperature (UHT procedure) has been one of thesubjects of our research and we developed procedures to control L-lactate in milk formonitoring bacterial fermentation. The possibility of measuring L-lactate in a few secondsdirectly in whole milk without any conventional preliminary treatment (deproteinization)was demonstrated. However, with some bacteria D-lactate is formed which is not detectedby the specific L-lactate biosensor. The research was then extended to develop biosensorsfor D-lactate exploiting a different pathway of lactate oxidation through D-lactatedehydrogenase instead of the oxidase which was unavailable commercially in this case. This research provides new applications of biosensors whilst eliminating interferencethrough microdialysis and pre-electrolysis procedures. Another group of metabolites of special interest for food industries are pesticides. Acetylchohesterase activity is inhibited by phosphoric and carbamic pesticides and theterm Total Anticholinesterase Activity (TAA) is being considered for adoption in Italy as ageneral index for the presence of pesticide in drinking water. New technologies based onPiezoelectric devices for following antigen-antibody reactions directly are considered, thistechnique can have application by the food industry for measuring low concentrations ofspecific metabolites such as Atrazine which was measured at ppb level.
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Sensors, Apr 20, 2020
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Springer eBooks, 2023
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Elsevier eBooks, 2023
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Springer eBooks, Jun 29, 2022
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Sensors and Actuators B-chemical, 2017
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Talanta, Feb 1, 2023
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Trends in Analytical Chemistry, Sep 1, 2022
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Journal of Hazardous Materials, 2021
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The Royal Society of Chemistry eBooks, Aug 28, 2019
Nowadays, foodborne allergies and illnesses have become a global menace on public health. Product... more Nowadays, foodborne allergies and illnesses have become a global menace on public health. Product mislabeling, accidental cross-contamination or intentional adulteration with low quality or unsafe ingredients for economic purposes could constitute a serious drawback: thus, safety and quality are of paramount importance in the food industry. Analytical strategies for on-site sensitive detection and screening of food allergens and food contaminants are becoming fundamental, since a huge development is being made in functional foods and new food manufacturing technologies. From the perspective of a quick and accurate analysis, immunosensors represent ideal tools that are able to provide a specific and fast response, since they are portable devices of low-cost and are easy to use. Among the different types of immunosensors, electrochemical immunosensors are widely accepted because of their large applicability such as screening, monitoring or diagnosing. This chapter summarizes a general overview of allergens, the applied nanotechnology and the fundamentals of immunosensors built to be applied in food analysis. The approaches used to develop electrochemical immunosensors for detecting foodborne allergens are emphasized.
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Chemical Communications, 2022
A dynamic interconversion between a dinuclear [FeIIFeIIIS2(GS)4]3− complex and a tetranuclear [Fe... more A dynamic interconversion between a dinuclear [FeIIFeIIIS2(GS)4]3− complex and a tetranuclear [FeII2FeIII2S4(GS)4]2− complex can be operative in the mitochondrial labile iron pool.
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Analytical Chemistry, Jun 2, 2020
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Biosensors, Mar 21, 2023
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Elsevier eBooks, 2012
Abstract: Development of immunoassays and immunosensors for detection and monitoring of cancer ma... more Abstract: Development of immunoassays and immunosensors for detection and monitoring of cancer markers is currently a major area of research and, as more markers are discovered and their role in disease becomes better understood, this will continue to grow. Success of these assays is largely due to the properties of the antibodies used to capture and detect the analyte, resulting from the high sensitivity and specificity of immunoglobulins. However, they are not without disadvantages and this has led to investigation into alternatives that maintain the binding abilities of antibodies, but minimise any associated problems. Affibodies are one such alternative.
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Analytica Chimica Acta, 1990
... 125 Improved potentiometric determination of potassium in whole blood and serum with a valino... more ... 125 Improved potentiometric determination of potassium in whole blood and serum with a valinomycin-treated silicone-rubber tubular electrode MARCO MASCINI * and ... 2 W Crowe, A Majevsky and L Mela, Am J Physiol, 233 (1977) C56 3 P. Anker, H Jenny, U Wuthier, R Asper ...
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Comprehensive Analytical Chemistry, 2016
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Talanta, Dec 1, 2016
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Papers by Giovanna Marrazza