Papers by Guilherme Domingos
Fundação Dom Cabral eBooks, Nov 10, 2021
A economia digital apresentou crescimento exponencial nos últimos anos, como resultado da rápida ... more A economia digital apresentou crescimento exponencial nos últimos anos, como resultado da rápida evolução da tecnologia de informática e das comunicações, permitindo não apenas a informatização de atividades existentes como também novos processos, produtos, serviços, métodos de comercialização e, inclusive, novos modos de vida ao incorporar a internet nos dispositivos digitais. Segundo a Organização para a Cooperação e Desenvolvimento Econômico (OCDE), a combinação de produtos digitais e sua interação com os mercados tecnológicos cria um ambiente diferente do seu equivalente no mundo físico. Suas propriedades, muitas vezes disruptivas, podem afetar as políticas governamentais de várias formas e, para serem efetivas, precisam ser consideradas para criar uma economia e sociedade digitais. É preciso transformar a estratégia digital em uma política de desenvolvimento. Mais fácil do que definir a economia digital é exemplificá-la com alguns de seus aspectos: habilidades próprias, equipamentos de computação e de comunicação, software, machine learning e serviços de atendimento ao público.
Scorpion sting accidents have a significant impact in Brazil, leading to increased hospitalizatio... more Scorpion sting accidents have a significant impact in Brazil, leading to increased hospitalizations and healthcare costs, especially in regions with high scorpion populations. The present study aimed to perform an epidemiological analysis of these accidents in Southeastern Brazil. It is an epidemiological, ecological, and mixed-design study. The methodological strategy involved the analysis of epidemiological bulletins provided by the Sistema de Informação de Agravos de Notificação (Sinan) from 2011 to 2022. The data revealed that 613,385 cases of accidental scorpion bites were reported. Minas Gerais had the highest number of cases (50.44%). Males, Caucasians, between 20 and 59 years old, with a low level of education, are the most affected. Victims sought medical attention within 3 hours of the bite, and 27.34% were on the fingers. About 89.7% of the cases were classified as mild, 95.33% were cured, and 0.78% died from the reported disease. The results highlight the urgent need for targeted prevention strategies, improved medical management, and community awareness campaigns to reduce the impact of scorpion stings in the southeastern region of Brazil.
The Lancet Respiratory Medicine
Background: Current management practices and outcomes in weaning from invasive mechanical ventila... more Background: Current management practices and outcomes in weaning from invasive mechanical ventilation are poorly understood. We aimed to describe the epidemiology, management, timings, risk for failure, and outcomes of weaning in patients requiring at least 2 days of invasive mechanical ventilation. Methods: WEAN SAFE was an international, multicentre, prospective, observational cohort study done in 481 intensive care units in 50 countries. Eligible participants were older than 16 years, admitted to a participating intensive care unit, and receiving mechanical ventilation for 2 calendar days or longer. We defined weaning initiation as the first attempt to separate a patient from the ventilator, successful weaning as no reintubation or death within 7 days of extubation, and weaning eligibility criteria based on positive end-expiratory pressure, fractional concentration of oxygen in inspired air, and vasopressors. The primary outcome was the proportion of patients successfully weaned at 90 days. Key secondary outcomes included weaning duration, timing of weaning events, factors associated with weaning delay and weaning failure, and hospital outcomes
Drugs, 2021
Stijn Blot 1* (ORCID: 0000-0003-2145-0345), Andries Van den Berge 1 (ORCID: 0000-0002-8630-5651),... more Stijn Blot 1* (ORCID: 0000-0003-2145-0345), Andries Van den Berge 1 (ORCID: 0000-0002-8630-5651), Philippe Montravers 3 (ORCID: 0000-0002-3422-5705), for the Abdominal Sepsis Study ("AbSeS") group on behalf of the Trials Group of the European Society of Intensive Care Medicine**
JOSÉ SERRA, Governador do Estado de São Paulo, no uso de suas atribuições legais e considerando a... more JOSÉ SERRA, Governador do Estado de São Paulo, no uso de suas atribuições legais e considerando a necessidade de atualização periódica dos dados cadas-trais de servidores e empregados públicos e militares, Decreta: Artigo 1º-Fica instituído o Recadastramento Anual de servidores, empregados públicos e militares em ati-vidade, no âmbito da Administração Direta, das Autar-quias, inclusive as de Regime Especial, e das Funda-ções instituídas ou mantidas pelo Estado. Artigo 2º-Os servidores e empregados públicos e militares em atividade deverão se recadastrar anual-mente, a partir do exercício de 2008, no mês do res-pectivo aniversário, com a finalidade de promover a atualização de seus dados cadastrais. § 1º-O disposto no "caput" deste artigo aplica-se também aos servidores, empregados públicos e milita-res afastados e licenciados. § 2º-No caso de servidores, empregados públicos e militares que cumulem cargo, emprego ou função públicos, o recadastramento deverá ser procedido em...
Portuguese Journal of Public Health, 2020
Intensive Care Medicine, 2019
Purpose: To describe the epidemiology of intra-abdominal infection in an international cohort of ... more Purpose: To describe the epidemiology of intra-abdominal infection in an international cohort of ICU patients according to a new system that classifies cases according to setting of infection acquisition (community-acquired, early onset hospital-acquired, and late-onset hospital-acquired), anatomical disruption (absent or present with localized or diffuse peritonitis), and severity of disease expression (infection, sepsis, and septic shock). We performed a multicenter (n = 309), observational, epidemiological study including adult ICU patients diagnosed with intra-abdominal infection. Risk factors for mortality were assessed by logistic regression analysis. The cohort included 2621 patients. Setting of infection acquisition was community-acquired in 31.6%, early onset hospital-acquired in 25%, and late-onset hospital-acquired in 43.4% of patients. Overall prevalence of antimicrobial resistance was 26.3% and difficult-to-treat resistant Gram-negative bacteria 4.3%, with great variation according to geographic region. No difference in prevalence of antimicrobial resistance was observed according to setting of infection acquisition. Overall mortality was 29.1%. Independent risk factors for mortality included late-onset hospitalacquired infection, diffuse peritonitis, sepsis, septic shock, older age, malnutrition, liver failure, congestive heart failure, antimicrobial resistance (either methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci, extended-spectrum beta-lactamase-producing Gram-negative bacteria, or carbapenem-resistant Gram-negative bacteria) and source control failure evidenced by either the need for surgical revision or persistent inflammation.
Intensive Care Medicine, 2015
Revista do Serviço Público, 2017
Revista do Serviço Público, 2017
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Papers by Guilherme Domingos