the main cause of death among pemphigus patients. The objective of this study was to find the pre... more the main cause of death among pemphigus patients. The objective of this study was to find the prevalence and factors associated with bacterial infections among PV inpatients. This retrospective study was conducted among 129 patients who were diagnosed with PV by dermatologists and admitted in the Institute of Dermatology Thailand, from 2011 to 2015. This study was approved by Ethical committees of Faculty of Public Health, Mahidol University and of the Institute of Dermatology. Data were from medical records and analyzed using SPSS for Windows. Overall, 86 subjects (31 males and 55 females) with 134 admissions were recruited into the study. The mean (SD) age was 46.8(15.1) years (ranged 17-84). From culture results, 122 (91.0%) had bacterial infections: 79 of 122 (64.8 %) had infection at admission and 43 (35.2%) acquired nosocomial infection. Multiple logistic regression revealed that antibiotic usage at admission was statistically significantly associated with bacterial infection (adjusted OR 8.45; 95% CI 1.6-43.3, p=0.001) while gender, age, number of admission, DM, pemphigus severity, corticosteroid use and length of stay did not show statistically significance. High prevalence of infection among PV patients in the present study is an urgent condition that needs further actions. Prompt detection of bacterial infection should be established during hospitalization especially among patients who had a history of antibiotic use prior to admission.
the main cause of death among pemphigus patients. The objective of this study was to find the pre... more the main cause of death among pemphigus patients. The objective of this study was to find the prevalence and factors associated with bacterial infections among PV inpatients. This retrospective study was conducted among 129 patients who were diagnosed with PV by dermatologists and admitted in the Institute of Dermatology Thailand, from 2011 to 2015. This study was approved by Ethical committees of Faculty of Public Health, Mahidol University and of the Institute of Dermatology. Data were from medical records and analyzed using SPSS for Windows. Overall, 86 subjects (31 males and 55 females) with 134 admissions were recruited into the study. The mean (SD) age was 46.8(15.1) years (ranged 17-84). From culture results, 122 (91.0%) had bacterial infections: 79 of 122 (64.8 %) had infection at admission and 43 (35.2%) acquired nosocomial infection. Multiple logistic regression revealed that antibiotic usage at admission was statistically significantly associated with bacterial infection (adjusted OR 8.45; 95% CI 1.6-43.3, p=0.001) while gender, age, number of admission, DM, pemphigus severity, corticosteroid use and length of stay did not show statistically significance. High prevalence of infection among PV patients in the present study is an urgent condition that needs further actions. Prompt detection of bacterial infection should be established during hospitalization especially among patients who had a history of antibiotic use prior to admission.
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