Lani Tabangay

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Address: Makati, Manila, Philippines

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Rizky Keumala Ansari Nasution

University of North Sumatra

forman erwin Siagian

Universitas Kristen Indonesia Jakarta

Universitas Sumatera Utara

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Papers by Lani Tabangay

Association between soil-transmitted helminthiasis and hemoglobin concentration in primary school children

Paediatrica Indonesiana, 2016

Objectives To determine the association between intestinal hel-minthiasis and hemoglobin (Hb) con... more Objectives To determine the association between intestinal hel-minthiasis and hemoglobin (Hb) concentration and to observe theeffect of single dose albendazole treatment on Hb concentration.Methods An experimental study was carried out from March toJuly 2002 on primary school children at Suka Village, Tiga PanahSubdistrict, Karo Regency, North Sumatera Province. From 366children who suffered from helminthiasis, 113 were selected assubjects by simple random sampling. Subjects were treated with asingle oral dose of 400 mg albendazole. Hb concentration wasexamined using the cyanide method twice i.e., prior to and threemonths after treatment with albendazole.Results It was found that among 113 subjects, the prevalences ofAscaris lumbricoides, Trichuris trichiura, and mixed infestation were18.3%, 40.4%, and 41.3%, respectively, while the prevalence ofanemia was 33.0%. There was no significant difference in age,gender, nutritional status, and mean Hb concentration betweenchildren sufferin...

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Associations between STH infection/non-treatment and performance in cognitive and educational domains among school-aged children following exclusion of outlier investigations using the Galbraith plot method

Associations between STH infection/non-treatment and performance in c... more

Summary of the impact of publication bias on respective outcome domains

Summary of the impact of publication bias on respective outcome domains.</p

Effect of STH infection/non-treatment on performance in cognitive and educational within strata of study designs, non-outlier investigations and study quality

Effect of STH infection/non-treatment on performance in cognitive and... more

Galbraith plot analysis to identify outliers among included studies of STH infection and performance in learning tests

Log SMD: logarithm of standardized mean difference; SE: Standard error. Studies that lie... more

GEOMETRIC MORPHOMETRIC ANALYSIS OF SHELL SHAPE VARIATION OF Littoria (Littorinidae) IN BANGKUNG MAPALAD, SASMUAN, PAMPANGA

Extensive studies have been carried out on the diversity, morphology, ecology and reproductive bi... more Extensive studies have been carried out on the diversity, morphology, ecology and reproductive biology of Littorinidae. Two species of Littoraria (Littorinidae)have been recorded to be present in Bangkung Mapalad, Sasmuan, Pampanga : Littoraria cf. angulifera and Littoraria cf. articulata . However, quantifiable morphometric data on shell shape variation is not available among these taxa in the area. This study aims to examine and identify snail species that thrive in Bangkung Mapalad using landmark-based geometric morphometric analysis. A freeware program tpsDig v. 2.30 was used for landmark digitization and the analysis of landmark data was done using Paleontological Statistics (PAST) v.2.17. The Principal Component Analysis of the 42 coordinates of the 21 landmarks combine to account for 85.814 % of the variation amongst the samples and showed separation between L. cf angulifera and L. cf articulata . Visualization of shell shape, relative to the mean shape, generated from thin-p...

Evaluating Meta-Analysis Research of Escherichia coli

Escherichia coli - Recent Advances on Physiology, Pathogenesis and Biotechnological Applications, Jul 12, 2017

This chapter summarizes the progress in Escherichia coli research that used the meta-analysis app... more This chapter summarizes the progress in Escherichia coli research that used the meta-analysis approach. Using systematic searches for E. coli literature, we tracked meta-analysis publications and analyzed them based on a number of parameters. These included subject/topic (epidemiology, clinical/intervention/prevention and environmental), geographical region (the Americas, Europe and Australasia) and clinical syndrome (enteric, renal, and sepsis/meningitis). These parameters were plotted in terms of time span to obtain a sense of dynamic change or its absence through the years since the turn of the twentieth century. In terms of region, topic and syndrome, highest meta-analysis productivity was attributed to the Americas, clinical/intervention/prevention and enteric, all of which took place in the last 5 years (2011-2016). Over the combined time span of 16 years, the Americas significantly dominated meta-analysis outputs when compared to Europe and Australasia (P = 0.003). In conclusion, our findings facilitate awareness of the progress in this field wherein the studied parameters were analyzed for patterns over time and differential rates of publication productivity.

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Characteristics of the included studies

Characteristics of the included studies.</p

The association between soil-transmitted helminth infection or no deworming on tests of learning with exclusion of identified outlier investigations

Diamond denotes the pooled standardized mean difference (SMD). Squares indicate the SMD ... more Diamond denotes the pooled standardized mean difference (SMD). Squares indicate the SMD in each study, with square sizes directly proportional to the weight contribution (%) of each study. Horizontal lines represent 95% confidence intervals (CI). The Z test for overall effect indicates non-significance given that P > 0.05. The chi-square test indicates that heterogeneity (P = 0.12, I2 = 33%) was reduced by outlier treatment. SD: standard deviation; CI: confidence interval; Std: standard; df: degree of freedom; I2: measure of variability expressed in %.</p

Summary flowchart of literature search

Summary flowchart of literature search.</p

Risk of bias analysis for intervention studies using cochrane collaborations’ tool

Risk of bias analysis for intervention studies using cochrane collaborations’ tool.</p

Comparison of pooled effects between STH infection and respective outcomes with and without co-prevalent Schistosoma infection

Comparison of pooled effects between STH infection and respective out... more

Risk of bias in observational studies using the Newcastle-Ottawa quality assessment scale

Risk of bias in observational studies using the Newcastle-Ottawa quality assessment scal... more

Associations of Polymorphisms in Anti-Müllerian Hormone (AMH Ile49Ser) and its Type II Receptor (AMHRII -482 A>G) on Reproductive Outcomes and Polycystic Ovary Syndrome: a Systematic Review and Meta-Analysis

Cellular Physiology and Biochemistry, 2016

Background/Aims: Reported associations of reproductive outcomes (RO) and polycystic ovary syndrom... more Background/Aims: Reported associations of reproductive outcomes (RO) and polycystic ovary syndrome (PCOS) with genotypes of the Ile49Ser and -482A>G polymorphisms in the Anti-Müllerian hormone (AMH) gene and its type II receptor (AMHRII), respectively, have conflicting results. Methods: PubMed, Google Scholar and Science Direct databases were searched for studies that investigated Ile49Ser and -482A>G in RO and PCOS. Using the metaanalytic approach, we estimated risk (odds ratio [OR] with 95% confidence intervals) using standard genetic models. Results: All calculated summary effects were non-significant. Overall associations of Ile49Ser and -482A>G with RO were absent (OR 0.95-0.99, P = 0.76-0.96) but implied increased risk in PCOS (OR 1.07-1.17, P = 0.49-0.55). Where heterogeneity of the pooled ORs were present, its sources were explored using the Galbraith plot. Detection and omission of the outlying studies in both polymorphisms not only erased heterogeneity of the reca...

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Association Between the FokI and ApaI Polymorphisms in the Vitamin D Receptor Gene and Intervertebral Disc Degeneration: A Systematic Review and Meta-Analysis

Genetic testing and molecular biomarkers, Jan 31, 2016

Evidence supporting an association of intervertebral disc degeneration (DD) with polymorphisms of... more Evidence supporting an association of intervertebral disc degeneration (DD) with polymorphisms of the vitamin D receptor (VDR) gene has been controversial. We perform a meta-analysis of these studies to determine if there was substantial evidence to support such an association between the VDR polymorphisms and DD. PubMed, Embase, and Science Direct databases were searched for studies that investigated associations of the FokI (rs2228570, rs10735810), and ApaI (rs7975253) polymorphisms of the VDR gene with DD. From the extracted genotype data from 14 publications, we estimated risk (odds ratio [OR] with 95% confidence intervals). Overall associations of FokI with DD were absent (OR 0.96-1.04, p = 0.73-0.95) with heterogeneity in the dominant and codominant models (pheteroegeneity <0.10, I(2) = 47-57%). Post-outlier pooled effects yielded dominant significance indicating reduced risk (OR 0.77, p = 0.01) with concomitant zero heterogeneity (I(2) = 0%). ApaI effects pointed to reduce...

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Associations of the A66G Methionine Synthase Reductase Polymorphism in Colorectal Cancer: A Systematic Review and Meta-Analysis

Biomarkers in Cancer, 2015

Inconsistency in the reported associations between the A66G polymorphism in the methionine syntha... more Inconsistency in the reported associations between the A66G polymorphism in the methionine synthase reductase (MTRR) gene and colorectal cancer (CRC) prompted a meta-analysis, so that we could obtain a more precise estimate. Databases searches of the published literature yielded 20 case-control studies from 17 articles (8,371 cases and 12,574 controls). We calculated pooled odds ratios (ORs) and 95% confidence intervals in three genetic comparisons (A allele, G allele, and A/G genotype). We found no evidence of overall associations between MTRR A66G and CRC risk (OR 0.96–1.05, P = 0.12–0.44). This was materially unchanged when reanalyzed without the Hardy-Weinberg equilibrium (HWE)-deviating studies (OR 0.97–1.06, P = 0.11–0.65). In the A allele comparison, however, outlier treatment generated significant protection (OR 0.91, P = 0.01). Combined removal of the outliers and HWE-deviating studies reflected this summary effect (OR 0.90, P = 0.01) as did the pooled OR from high-quality ...

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Soil-transmitted helminth infection, loss of education and cognitive impairment in school-aged children: A systematic review and meta-analysis

PLoS neglected tropical diseases, 2018

Evidence of an adverse influence of soil transmitted helminth (STH) infections on cognitive funct... more Evidence of an adverse influence of soil transmitted helminth (STH) infections on cognitive function and educational loss is equivocal. Prior meta-analyses have focused on randomized controlled trials only and have not sufficiently explored the potential for disparate influence of STH infection by cognitive domain. We re-examine the hypothesis that STH infection is associated with cognitive deficit and educational loss using data from all primary epidemiologic studies published between 1992 and 2016. Medline, Biosis and Web of Science were searched for original studies published in the English language. Cognitive function was defined in four domains (learning, memory, reaction time and innate intelligence) and educational loss in two domains (attendance and scholastic achievement). Pooled effect across studies were calculated as standardized mean differences (SMD) to compare cognitive and educational measures for STH infected/non-dewormed children versus STH uninfected /dewormed chi...

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Association between soil-transmitted helminthiasis and hemoglobin concentration in primary school children

Paediatrica Indonesiana, 2016

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