Carbon dioxide (CO2) emissions from burning fossil fuels play a crucial role in global warming/cl... more Carbon dioxide (CO2) emissions from burning fossil fuels play a crucial role in global warming/climate change. The effective removal of CO2 from the point sources or atmosphere (CO2 capture), its conversion to value-added products (CO2 utilization), and long-term geological storage, or CO2 sequestration, has captured the attention of several researchers and policymakers. This review paper illustrates all kinds of CO2 capture/separation processes and the challenges faced in deploying these technologies. This review described the research efforts put forth in gas separation technologies. Recent advances in the existing gas separation technologies have been highlighted, and future directives for commercial deployment have also been outlined.
The objective of the present study titled “Stress and Parental Involvement” was to see the effect... more The objective of the present study titled “Stress and Parental Involvement” was to see the effect of parental involvement on stress in children and whether it exerts positive or negative effect on children. Stress is a state of affair involving demand on physical or mental energy. Any event may create stress whether it is good or bad. The stressor can be anything, environmental or physical or emotional. When stress is within the comfort zone, it can help in staying focused, energetic and alert. Parental involvement has been recognized as the most important factor to influence the childhood and adulthood. Educational success is one of the primary outcome of parental involvement. Such children also become well adjusted in the society. Parental involvement also boosts self-esteem and a feeling of self worth in children. They are less likely to get depressed. Children and their parents (60 samples) were selected as sample by incidental cum purposive sampling method. The tools used were ...
This paper has focused on abrasive wear and abrasion heating of Mg-and Al-based B 4 C and Cr rein... more This paper has focused on abrasive wear and abrasion heating of Mg-and Al-based B 4 C and Cr reinforced composites. The B 4 C and Cr have been added in 5% in the Mg-and Al-matrices and their composites have been fabricated by a squeezed stir casting method. The matrices and composites are evaluated and characterized for microstructure, hardness and X-ray diffraction. The abrasive wear and temperature rise during abrasive wear tests are carried out using a tribo-tester machine. The microstructure of Mg-and Al-matrices and their composites mainly show a uniform distribution of the B 4 C and Cr reinforcements. The hardness of the composites enhanced upto 72% by including B 4 C and 30 to 37% in the case of Cr composites in comparison to Mg-and Al-matrices. Temperature rise during abrasive is found more in the case of B 4 C reinforced composites in comparison to Cr amalgam composites and the abrasive resistance of B 4 C composite is high in comparison to Cr amalgam composites. The wear rate of boron carbide composites is approximately 2-6 times lower than the Mg matrix under different conditions. SEM image analysis mainly shows the cutting and ploughing material removal mechanism in abrasive wear.
In this study, optimization of the corrosion rate (CR) of Mg-composites has been evaluated by var... more In this study, optimization of the corrosion rate (CR) of Mg-composites has been evaluated by varying the concentration, reinforcement percentage, and immersion time. As prime material, pure Mg is preferred for this research and chromium (Cr) consider as a reinforcing material with different percentages. CR (miles/yr) has been optimized by varying parameters such as reinforcement percentage as 3%, 5% and 7% including NaCl immersion medium (%) as 2.4%, 3.5% and 4.7% with immersion time (h) such as 48h, 72h and 96h. By using, DOF, minimal CR has been measured with the assistance of Minitab Software having ANOVA and Taguchi approaches. Optimized results reveal that the percentage of corrosion solution is influenced upto 66.10%, reinforcement percentage contributed to 27.56% and immersion time influenced upto 2.81%. An optimized combination of CR is 7wt. % Cr with 2.4% NaCl for 96h. However, microscopy results illustrate shallow crack boundaries in Mg/Cr composites due to its chemical reaction in alkaline solution.
This work presents a novel organic–inorganic nanocomposite ion exchanger synthesized through an i... more This work presents a novel organic–inorganic nanocomposite ion exchanger synthesized through an in-situ approach that exhibits exceptional ion exchange capacities (IEC~1.95 meq g –1 ). Through solution casting, polycarbazole (PCz) Sn(IV) phosphate ion-exchange membranes were also pre- pared. Several instruments were utilized to characterize membranes including scanning electron microscopy with thermogravimetric analysis, Fourier-transform infrared spectroscopy, X-ray diffraction, transmission electron microscopy, and energy-dispersive X-ray spectroscopy. A few parameters, including the working pH range (5–8), the response time (20 s), the linear response range (1.0 × 10 –7 M to 1.0 × 10 –1 M), and the detection limit (1.0 × 10 –7 M), were measured following fabrication of Cu 2+ selective membrane electrodes. It also serves as an indicator electrode during the Cu 2+ potentiometric titration.
Journal of emerging technologies and innovative research, 2019
Wireless power transmission (WPT) has been pulling in a wide scope of subjects in different field... more Wireless power transmission (WPT) has been pulling in a wide scope of subjects in different fields and furthermore become an exceptionally dynamic research region on account of their potential in giving high innovation to our everyday lives. The remote power transmission will be required to use soon on the grounds that this innovation empowers the transmission of electrical vitality from a power source to an electrical burden over an air hole without interconnecting wires. In spite of intensity misfortune during the transmission procedure is unavoidable, a few options can be deciphered to alleviate this issue. So as to limit power misfortunes in the influence circulation organize, remote power transmission has been known for a considerable length of time to clean wellsprings of power. Right now, complete a pilot study to present the current advances of remote power transmission, their ongoing innovation just as its future patterns. Moreover, likewise portray a lot of utilizations in remote transmission.
Forensic science is a study of science to criminals and civil laws. Digital forensics is the part... more Forensic science is a study of science to criminals and civil laws. Digital forensics is the part of forensic science relating to proof found in computers and advanced storage media. Forensic examiners gather, protect and break down logical confirmations over the span of examination. Digital information contains data as content, pictures, sound, video and so on. These days numerous cybercrime cases, for example, hacking, banking cheats, phishing, email spamming, etc., have developed which are connected with a computerized information. Since the digital investigation is turning into an expanding concern, numerous digital forensic tools have been created to manage the difficulties of exploring computerized wrongdoings. The motivation behind digital forensics strategies is to look, protect and extract data on advanced frameworks to discover potential confirmations to exhibit them in the courtroom. In this paper, we have discussed five kinds of forensics namely Network Forensics, Live F...
Proceedings of the Fourteenth Workshop on Semantic Evaluation, 2020
Social media is abundant in visual and textual information presented together or in isolation. Me... more Social media is abundant in visual and textual information presented together or in isolation. Memes are the most popular form, belonging to the former class. In this paper, we present our approaches for the Memotion Analysis problem as posed in SemEval-2020 Task 8. The goal of this task is to classify memes based on their emotional content and sentiment. We leverage techniques from Natural Language Processing (NLP) and Computer Vision (CV) towards the sentiment classification of internet memes (Subtask A). We consider Bimodal (text and image) as well as Unimodal (text-only) techniques in our study ranging from the Naïve Bayes classifier to Transformer-based approaches. Our results show that a text-only approach, a simple Feed Forward Neural Network (FFNN) with Word2vec embeddings as input, performs superior to all the others. We stand first in the Sentiment analysis task with a relative improvement of 63% over the baseline macro-F1 score. Our work is relevant to any task concerned with the combination of different modalities.
Nanotechnology has today turned out to be a buzzword. Its expansion in a different field is pheno... more Nanotechnology has today turned out to be a buzzword. Its expansion in a different field is phenomenal. But for some reason, it has been holding the rate of development. To count reason behind being its failure despite such promising properties is its high-cost production and potential harm to nature. Beside the less significant amount of production, there is a need for the eco-friendly, less toxic and cleaner method of its production. It could not have been more favorable, in case if it could lead to an increase in production at the same time in its efficiency too. Algae mediated biosynthesis of the nanoparticle is one of the probable solutions of the above-mentioned drawbacks. This review article focuses on the synthesis of nanoparticles with help of algae and their potential benefits over conventional based methods. It takes into consideration, the formation of nanoparticle through cyanobacteria, microalgae, and macroalgae.
Due to hectic life schedule and adulthood results in degradation of organic elements at a faster ... more Due to hectic life schedule and adulthood results in degradation of organic elements at a faster rate. This shows various health problems like knee joint pain, back joint pain, cartilage tearing and degradation of bones, etc. To reduce these effects, there is need replacement and implantation. Currently, some implant, materials are being used such as Ti and its alloys, SS and Cr-Co alloys. But testing shows some issues like constantly enduring remodeling and modification after implantation. Therefore, a new bio-compatible material Mg and its alloys show diagnostic positive results in muscles and bone tissues. During testing, the mechanical properties of Mg are similar to natural bone, which shows beneficial bio-compatibility of the material for the improvement of implant materials. Different Mg alloys are also tested such as Mg-Zn, Mg-Zn-Ti etc.... But all of Mg alloys having problems like: High toxicity, High corrosion rate and repeated surgeries so overall results are still negati...
A polycarbazole-Sn(iv) arsenotungstate (Pcz-SnAT) nanocomposite cation exchanger membrane (CEM) w... more A polycarbazole-Sn(iv) arsenotungstate (Pcz-SnAT) nanocomposite cation exchanger membrane (CEM) was prepared via the casting solution technique utilizing polycarbazole-Sn(iv) arsenotungstate and PVC (polyvinyl chloride) as a binder.
Presently, most of the treatment strategies for cancer are focused on the surgical removal of can... more Presently, most of the treatment strategies for cancer are focused on the surgical removal of cancerous tumors, along with physical and chemical treatment such as radiotherapy and chemotherapy, respectively. The primary issue associated with these methods is the inhibition of normal cell growth and serious side effects associated with systemic toxicity. The traditional chemotherapeutics which were delivered systemically were inadequate and had serious dose limiting side effects. Recent advances in the development of chemotherapeutics have simultaneously paved the way for efficient targeted drug delivery. Despite the advances in the field of oncogenic drugs, several limitations remain, such as early blood clearance, acquired resistance against cytotoxic agents, toxicity associated with chemotherapeutics, and site-specific drug delivery. Hence, this review article focuses on the recent scientific advancements made in different types of drug delivery systems, including, organic nanocarriers (polymers, albumins, liposomes, and micelles), inorganic nanocarriers (mesoporous silica nanoparticles, gold nanoparticles, platinum nanoparticles, and carbon nanotubes), aptamers, antibody-drug conjugates, and peptides. These targeted drug delivery approaches offer numerous advantages such as site-specific drug delivery, minimal toxicity, better bioavailability, and an increased overall efficacy of the chemotherapeutics.
1Project Management Trainee, Sunteck Realty, Mumbai, Maharashtra 2Structural Engineer, A plus B I... more 1Project Management Trainee, Sunteck Realty, Mumbai, Maharashtra 2Structural Engineer, A plus B Infrastructure Pvt. Ltd, 3Residential Building Consultant, Jodhpur, Rajasthan ---------------------------------------------------------------------***---------------------------------------------------------------------Abstract The silica powder based concrete (SPC) is one innovation which provides strength, durability and other properties to concrete. In this work we tested M50 grade concrete cubes of size 150x150x150 with Nano silica powder and Class C fly-ash and tested their properties for 7, 14 & 28 days respectively. Cement was replaced with varying percentages of Nano silica and the results were tabulated. The results showed that 10% replacement of cement with silica powder gave the maximum strength to the concrete, increased its initial strength and also durability.
ABSTACT: The need for robotic technology transfer from the research labs to civilian applications... more ABSTACT: The need for robotic technology transfer from the research labs to civilian applications is now a big problem for the robotic community. In the marine robotics market, it is especially important to equip the robot with a safe and highly reliable Navigation Guidance and Control (NGC) system that allows the Unmanned Surface Vehicle (USV) to navigate safely even in the presence of human activities such as commercial and recreational traffic, swimming, rowers, etc. A crucial factor for successful autonomous navigation is the robot's ability to detect the existence of an unpredictable, potentially moving, obstacle well in advance. This role represents the base brick for developing smart enough collision avoidance systems to reactively detect unexpected obstacles and execute the appropriate avoidance maneuvers to prevent collisions in a safe manner. The present paper describes the design of an innovative sensor for the detection of obstacles, combining both passive and active...
Introduction: Gestational diabetes mellitus (GDM) has been observed to be associated with increas... more Introduction: Gestational diabetes mellitus (GDM) has been observed to be associated with increased perinatal morbidity and mortality. GDM is becoming a public health concern globally as well as in India with fast increasing trend. It affects approximately 14% of all pregnancies. Most of the literature available has focused on traditional risk factors while this article has thrown light on modifiable ones. Objective: To study the modifiable risk factors for developing GDM in pregnant women based on physical examination and personal history. Materials and Methods: A hospital based case control study was conducted in Lady Hardinge Medical College and associated hospital with a sample size of 104 (52 cases & 52 controls). Pregnant women with gestational diabetes mellitus as diagnosed by abnormal oral Glucose Tolerance Test (OGTT) were taken as cases and Pregnant women who have completed 24 weeks of gestation and who tested negative on Glucose Challenge test (GCT) were selected as contr...
Background: Gestational diabetes mellitus (GDM) has been observed to be associated with increased... more Background: Gestational diabetes mellitus (GDM) has been observed to be associated with increased perinatal morbidity and mortality. GDM is becoming a public health concern globally as well as in India with fast increasing trend. It affects approximately 14% of all pregnancies. Studies on the association of food items having high glycaemic index with GDM risk are sparse. Most of the literature has focused on typical risk factors like advanced maternal age, family history of diabetes mellitus, history of abortions, previous history of GDM. Objective: To assess the risk of developing GDM in pregnant women consuming food items with high glycemic index. Material and Methods: A hospital based case control study was conducted in Lady Hardinge Medical College and associated hospital with a sample size of 104 (52 cases & 52 controls). For dietary history a validated quantitative food frequency questionnaire was used. The usual pattern of eating during days, weeks and months were asked. The ...
Proceedings of the 18th International Conference on Signal Processing and Multimedia Applications, 2021
Recent developments in machine and deep learning have made it possible to expand the realms of tr... more Recent developments in machine and deep learning have made it possible to expand the realms of traditional audio pattern recognition to real-time and practical applications. This work proposes a novel framework for robust bird species identification using the neural network (RoBINN) based on their unique vocal signatures. To make the network robust and efficient, data augmentation is performed to create synthetic training samples for bird species with less available recordings. Further, inherent properties of audio signals are suitably leveraged via effective speech recognition-based feature engineering techniques to develop an end-to-end convolutional neural network (CNN). Additionally, the proposed model architecture for the CNN framework employs residual learning and attention mechanism to generate attention-aware features, which enhances the overall accuracy of birdcall identification. The proposed architecture employs an exhaustive dataset with 21375 recordings corresponding to 264 bird species. Experimental results validate the proposed bird species classification technique in terms of accuracy, F1-score, and binary cross-entropy loss.
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2021
The SWI/SNF subfamily remodelers (SWI/SNF and RSC) generally promote gene expression by displacin... more The SWI/SNF subfamily remodelers (SWI/SNF and RSC) generally promote gene expression by displacing or evicting nucleosomes at the promoter regions. Their action creates a nucleosome-depleted region where transcription machinery accesses the DNA. Their involvement has been shown critical for inducing stress-responsive transcription programs. Although the role of SWI/SNF and RSC complexes in transcription regulation of heat shock responsive genes is well studied, their involvement at other pathways such as unfolded protein response (UPR) and protein quality control (PQC) is less known. This study shows that SWI/SNF occupies promoters of UPR, HSP and PQC genes in response to unfolded protein stress, and its recruitment at UPR promoters depends on Hac1 transcription factor and other epigenetic factors like Ada2 and Ume6. Disruption of SWI/SNF's activity does not affect the remodeling of these promoters or gene expression. However, inactivation of RSC and SWI/SNF together diminishes expression of most of the UPR, HSP and PQC genes tested. Furthermore, RSC and SWI/SNF colocalize at these promoters, suggesting that these two remodelers functionally cooperate to induce stress-responsive genes under proteotoxic conditions.
National Journal of Physiology, Pharmacy and Pharmacology, 2021
Background: Constructing blueprint for assessment is an important approach evolving today and bei... more Background: Constructing blueprint for assessment is an important approach evolving today and being emphasized to assess the medical students. It is necessary that the items in the question paper should match the course and a proportional weightage should be given to each competency of the curriculum with respect to its domain and clinical relevance. Aim and Objectives: The aim of the study was to prepare test blueprints for 2 nd year medical undergraduate syllabus of Pharmacology papers-Paper I and Paper II. Materials and Methods: This study was carried out in the Pharmacology Department of Geetanjali Medical College, Udaipur. All the competencies based on the knowledge domain of the 2 nd-year medical undergraduate curriculum for the Indian medical graduate were divided into two parts for theory paper I and paper II of pharmacology. Each competency or its subdivision was given pharmacological and clinical importance from score 1 to 3 and weightage was calculated for each competency. After devising both the blueprints, they were sent by email for validation by the peers and experts in the field of pharmacology. Results: Two final blueprints were prepared each for Papers I and II for summative theory assessment in pharmacology. General pharmacology carried the maximum weightage in Paper I which was found to be 30 marks out of 100 followed by 16 marks for central nervous system. In Paper II weightage of antimicrobial drugs was highest, that is, 35 marks followed by hormonal and related drugs which was 21 marks out of 100. Conclusion: Blueprints should be executed as an essential part of preparing the theory papers for all subjects. The blueprints should be periodically reviewed by the experts in the field and redesigned as per the changes in the curriculum.
Carbon dioxide (CO2) emissions from burning fossil fuels play a crucial role in global warming/cl... more Carbon dioxide (CO2) emissions from burning fossil fuels play a crucial role in global warming/climate change. The effective removal of CO2 from the point sources or atmosphere (CO2 capture), its conversion to value-added products (CO2 utilization), and long-term geological storage, or CO2 sequestration, has captured the attention of several researchers and policymakers. This review paper illustrates all kinds of CO2 capture/separation processes and the challenges faced in deploying these technologies. This review described the research efforts put forth in gas separation technologies. Recent advances in the existing gas separation technologies have been highlighted, and future directives for commercial deployment have also been outlined.
The objective of the present study titled “Stress and Parental Involvement” was to see the effect... more The objective of the present study titled “Stress and Parental Involvement” was to see the effect of parental involvement on stress in children and whether it exerts positive or negative effect on children. Stress is a state of affair involving demand on physical or mental energy. Any event may create stress whether it is good or bad. The stressor can be anything, environmental or physical or emotional. When stress is within the comfort zone, it can help in staying focused, energetic and alert. Parental involvement has been recognized as the most important factor to influence the childhood and adulthood. Educational success is one of the primary outcome of parental involvement. Such children also become well adjusted in the society. Parental involvement also boosts self-esteem and a feeling of self worth in children. They are less likely to get depressed. Children and their parents (60 samples) were selected as sample by incidental cum purposive sampling method. The tools used were ...
This paper has focused on abrasive wear and abrasion heating of Mg-and Al-based B 4 C and Cr rein... more This paper has focused on abrasive wear and abrasion heating of Mg-and Al-based B 4 C and Cr reinforced composites. The B 4 C and Cr have been added in 5% in the Mg-and Al-matrices and their composites have been fabricated by a squeezed stir casting method. The matrices and composites are evaluated and characterized for microstructure, hardness and X-ray diffraction. The abrasive wear and temperature rise during abrasive wear tests are carried out using a tribo-tester machine. The microstructure of Mg-and Al-matrices and their composites mainly show a uniform distribution of the B 4 C and Cr reinforcements. The hardness of the composites enhanced upto 72% by including B 4 C and 30 to 37% in the case of Cr composites in comparison to Mg-and Al-matrices. Temperature rise during abrasive is found more in the case of B 4 C reinforced composites in comparison to Cr amalgam composites and the abrasive resistance of B 4 C composite is high in comparison to Cr amalgam composites. The wear rate of boron carbide composites is approximately 2-6 times lower than the Mg matrix under different conditions. SEM image analysis mainly shows the cutting and ploughing material removal mechanism in abrasive wear.
In this study, optimization of the corrosion rate (CR) of Mg-composites has been evaluated by var... more In this study, optimization of the corrosion rate (CR) of Mg-composites has been evaluated by varying the concentration, reinforcement percentage, and immersion time. As prime material, pure Mg is preferred for this research and chromium (Cr) consider as a reinforcing material with different percentages. CR (miles/yr) has been optimized by varying parameters such as reinforcement percentage as 3%, 5% and 7% including NaCl immersion medium (%) as 2.4%, 3.5% and 4.7% with immersion time (h) such as 48h, 72h and 96h. By using, DOF, minimal CR has been measured with the assistance of Minitab Software having ANOVA and Taguchi approaches. Optimized results reveal that the percentage of corrosion solution is influenced upto 66.10%, reinforcement percentage contributed to 27.56% and immersion time influenced upto 2.81%. An optimized combination of CR is 7wt. % Cr with 2.4% NaCl for 96h. However, microscopy results illustrate shallow crack boundaries in Mg/Cr composites due to its chemical reaction in alkaline solution.
This work presents a novel organic–inorganic nanocomposite ion exchanger synthesized through an i... more This work presents a novel organic–inorganic nanocomposite ion exchanger synthesized through an in-situ approach that exhibits exceptional ion exchange capacities (IEC~1.95 meq g –1 ). Through solution casting, polycarbazole (PCz) Sn(IV) phosphate ion-exchange membranes were also pre- pared. Several instruments were utilized to characterize membranes including scanning electron microscopy with thermogravimetric analysis, Fourier-transform infrared spectroscopy, X-ray diffraction, transmission electron microscopy, and energy-dispersive X-ray spectroscopy. A few parameters, including the working pH range (5–8), the response time (20 s), the linear response range (1.0 × 10 –7 M to 1.0 × 10 –1 M), and the detection limit (1.0 × 10 –7 M), were measured following fabrication of Cu 2+ selective membrane electrodes. It also serves as an indicator electrode during the Cu 2+ potentiometric titration.
Journal of emerging technologies and innovative research, 2019
Wireless power transmission (WPT) has been pulling in a wide scope of subjects in different field... more Wireless power transmission (WPT) has been pulling in a wide scope of subjects in different fields and furthermore become an exceptionally dynamic research region on account of their potential in giving high innovation to our everyday lives. The remote power transmission will be required to use soon on the grounds that this innovation empowers the transmission of electrical vitality from a power source to an electrical burden over an air hole without interconnecting wires. In spite of intensity misfortune during the transmission procedure is unavoidable, a few options can be deciphered to alleviate this issue. So as to limit power misfortunes in the influence circulation organize, remote power transmission has been known for a considerable length of time to clean wellsprings of power. Right now, complete a pilot study to present the current advances of remote power transmission, their ongoing innovation just as its future patterns. Moreover, likewise portray a lot of utilizations in remote transmission.
Forensic science is a study of science to criminals and civil laws. Digital forensics is the part... more Forensic science is a study of science to criminals and civil laws. Digital forensics is the part of forensic science relating to proof found in computers and advanced storage media. Forensic examiners gather, protect and break down logical confirmations over the span of examination. Digital information contains data as content, pictures, sound, video and so on. These days numerous cybercrime cases, for example, hacking, banking cheats, phishing, email spamming, etc., have developed which are connected with a computerized information. Since the digital investigation is turning into an expanding concern, numerous digital forensic tools have been created to manage the difficulties of exploring computerized wrongdoings. The motivation behind digital forensics strategies is to look, protect and extract data on advanced frameworks to discover potential confirmations to exhibit them in the courtroom. In this paper, we have discussed five kinds of forensics namely Network Forensics, Live F...
Proceedings of the Fourteenth Workshop on Semantic Evaluation, 2020
Social media is abundant in visual and textual information presented together or in isolation. Me... more Social media is abundant in visual and textual information presented together or in isolation. Memes are the most popular form, belonging to the former class. In this paper, we present our approaches for the Memotion Analysis problem as posed in SemEval-2020 Task 8. The goal of this task is to classify memes based on their emotional content and sentiment. We leverage techniques from Natural Language Processing (NLP) and Computer Vision (CV) towards the sentiment classification of internet memes (Subtask A). We consider Bimodal (text and image) as well as Unimodal (text-only) techniques in our study ranging from the Naïve Bayes classifier to Transformer-based approaches. Our results show that a text-only approach, a simple Feed Forward Neural Network (FFNN) with Word2vec embeddings as input, performs superior to all the others. We stand first in the Sentiment analysis task with a relative improvement of 63% over the baseline macro-F1 score. Our work is relevant to any task concerned with the combination of different modalities.
Nanotechnology has today turned out to be a buzzword. Its expansion in a different field is pheno... more Nanotechnology has today turned out to be a buzzword. Its expansion in a different field is phenomenal. But for some reason, it has been holding the rate of development. To count reason behind being its failure despite such promising properties is its high-cost production and potential harm to nature. Beside the less significant amount of production, there is a need for the eco-friendly, less toxic and cleaner method of its production. It could not have been more favorable, in case if it could lead to an increase in production at the same time in its efficiency too. Algae mediated biosynthesis of the nanoparticle is one of the probable solutions of the above-mentioned drawbacks. This review article focuses on the synthesis of nanoparticles with help of algae and their potential benefits over conventional based methods. It takes into consideration, the formation of nanoparticle through cyanobacteria, microalgae, and macroalgae.
Due to hectic life schedule and adulthood results in degradation of organic elements at a faster ... more Due to hectic life schedule and adulthood results in degradation of organic elements at a faster rate. This shows various health problems like knee joint pain, back joint pain, cartilage tearing and degradation of bones, etc. To reduce these effects, there is need replacement and implantation. Currently, some implant, materials are being used such as Ti and its alloys, SS and Cr-Co alloys. But testing shows some issues like constantly enduring remodeling and modification after implantation. Therefore, a new bio-compatible material Mg and its alloys show diagnostic positive results in muscles and bone tissues. During testing, the mechanical properties of Mg are similar to natural bone, which shows beneficial bio-compatibility of the material for the improvement of implant materials. Different Mg alloys are also tested such as Mg-Zn, Mg-Zn-Ti etc.... But all of Mg alloys having problems like: High toxicity, High corrosion rate and repeated surgeries so overall results are still negati...
A polycarbazole-Sn(iv) arsenotungstate (Pcz-SnAT) nanocomposite cation exchanger membrane (CEM) w... more A polycarbazole-Sn(iv) arsenotungstate (Pcz-SnAT) nanocomposite cation exchanger membrane (CEM) was prepared via the casting solution technique utilizing polycarbazole-Sn(iv) arsenotungstate and PVC (polyvinyl chloride) as a binder.
Presently, most of the treatment strategies for cancer are focused on the surgical removal of can... more Presently, most of the treatment strategies for cancer are focused on the surgical removal of cancerous tumors, along with physical and chemical treatment such as radiotherapy and chemotherapy, respectively. The primary issue associated with these methods is the inhibition of normal cell growth and serious side effects associated with systemic toxicity. The traditional chemotherapeutics which were delivered systemically were inadequate and had serious dose limiting side effects. Recent advances in the development of chemotherapeutics have simultaneously paved the way for efficient targeted drug delivery. Despite the advances in the field of oncogenic drugs, several limitations remain, such as early blood clearance, acquired resistance against cytotoxic agents, toxicity associated with chemotherapeutics, and site-specific drug delivery. Hence, this review article focuses on the recent scientific advancements made in different types of drug delivery systems, including, organic nanocarriers (polymers, albumins, liposomes, and micelles), inorganic nanocarriers (mesoporous silica nanoparticles, gold nanoparticles, platinum nanoparticles, and carbon nanotubes), aptamers, antibody-drug conjugates, and peptides. These targeted drug delivery approaches offer numerous advantages such as site-specific drug delivery, minimal toxicity, better bioavailability, and an increased overall efficacy of the chemotherapeutics.
1Project Management Trainee, Sunteck Realty, Mumbai, Maharashtra 2Structural Engineer, A plus B I... more 1Project Management Trainee, Sunteck Realty, Mumbai, Maharashtra 2Structural Engineer, A plus B Infrastructure Pvt. Ltd, 3Residential Building Consultant, Jodhpur, Rajasthan ---------------------------------------------------------------------***---------------------------------------------------------------------Abstract The silica powder based concrete (SPC) is one innovation which provides strength, durability and other properties to concrete. In this work we tested M50 grade concrete cubes of size 150x150x150 with Nano silica powder and Class C fly-ash and tested their properties for 7, 14 & 28 days respectively. Cement was replaced with varying percentages of Nano silica and the results were tabulated. The results showed that 10% replacement of cement with silica powder gave the maximum strength to the concrete, increased its initial strength and also durability.
ABSTACT: The need for robotic technology transfer from the research labs to civilian applications... more ABSTACT: The need for robotic technology transfer from the research labs to civilian applications is now a big problem for the robotic community. In the marine robotics market, it is especially important to equip the robot with a safe and highly reliable Navigation Guidance and Control (NGC) system that allows the Unmanned Surface Vehicle (USV) to navigate safely even in the presence of human activities such as commercial and recreational traffic, swimming, rowers, etc. A crucial factor for successful autonomous navigation is the robot's ability to detect the existence of an unpredictable, potentially moving, obstacle well in advance. This role represents the base brick for developing smart enough collision avoidance systems to reactively detect unexpected obstacles and execute the appropriate avoidance maneuvers to prevent collisions in a safe manner. The present paper describes the design of an innovative sensor for the detection of obstacles, combining both passive and active...
Introduction: Gestational diabetes mellitus (GDM) has been observed to be associated with increas... more Introduction: Gestational diabetes mellitus (GDM) has been observed to be associated with increased perinatal morbidity and mortality. GDM is becoming a public health concern globally as well as in India with fast increasing trend. It affects approximately 14% of all pregnancies. Most of the literature available has focused on traditional risk factors while this article has thrown light on modifiable ones. Objective: To study the modifiable risk factors for developing GDM in pregnant women based on physical examination and personal history. Materials and Methods: A hospital based case control study was conducted in Lady Hardinge Medical College and associated hospital with a sample size of 104 (52 cases & 52 controls). Pregnant women with gestational diabetes mellitus as diagnosed by abnormal oral Glucose Tolerance Test (OGTT) were taken as cases and Pregnant women who have completed 24 weeks of gestation and who tested negative on Glucose Challenge test (GCT) were selected as contr...
Background: Gestational diabetes mellitus (GDM) has been observed to be associated with increased... more Background: Gestational diabetes mellitus (GDM) has been observed to be associated with increased perinatal morbidity and mortality. GDM is becoming a public health concern globally as well as in India with fast increasing trend. It affects approximately 14% of all pregnancies. Studies on the association of food items having high glycaemic index with GDM risk are sparse. Most of the literature has focused on typical risk factors like advanced maternal age, family history of diabetes mellitus, history of abortions, previous history of GDM. Objective: To assess the risk of developing GDM in pregnant women consuming food items with high glycemic index. Material and Methods: A hospital based case control study was conducted in Lady Hardinge Medical College and associated hospital with a sample size of 104 (52 cases & 52 controls). For dietary history a validated quantitative food frequency questionnaire was used. The usual pattern of eating during days, weeks and months were asked. The ...
Proceedings of the 18th International Conference on Signal Processing and Multimedia Applications, 2021
Recent developments in machine and deep learning have made it possible to expand the realms of tr... more Recent developments in machine and deep learning have made it possible to expand the realms of traditional audio pattern recognition to real-time and practical applications. This work proposes a novel framework for robust bird species identification using the neural network (RoBINN) based on their unique vocal signatures. To make the network robust and efficient, data augmentation is performed to create synthetic training samples for bird species with less available recordings. Further, inherent properties of audio signals are suitably leveraged via effective speech recognition-based feature engineering techniques to develop an end-to-end convolutional neural network (CNN). Additionally, the proposed model architecture for the CNN framework employs residual learning and attention mechanism to generate attention-aware features, which enhances the overall accuracy of birdcall identification. The proposed architecture employs an exhaustive dataset with 21375 recordings corresponding to 264 bird species. Experimental results validate the proposed bird species classification technique in terms of accuracy, F1-score, and binary cross-entropy loss.
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2021
The SWI/SNF subfamily remodelers (SWI/SNF and RSC) generally promote gene expression by displacin... more The SWI/SNF subfamily remodelers (SWI/SNF and RSC) generally promote gene expression by displacing or evicting nucleosomes at the promoter regions. Their action creates a nucleosome-depleted region where transcription machinery accesses the DNA. Their involvement has been shown critical for inducing stress-responsive transcription programs. Although the role of SWI/SNF and RSC complexes in transcription regulation of heat shock responsive genes is well studied, their involvement at other pathways such as unfolded protein response (UPR) and protein quality control (PQC) is less known. This study shows that SWI/SNF occupies promoters of UPR, HSP and PQC genes in response to unfolded protein stress, and its recruitment at UPR promoters depends on Hac1 transcription factor and other epigenetic factors like Ada2 and Ume6. Disruption of SWI/SNF's activity does not affect the remodeling of these promoters or gene expression. However, inactivation of RSC and SWI/SNF together diminishes expression of most of the UPR, HSP and PQC genes tested. Furthermore, RSC and SWI/SNF colocalize at these promoters, suggesting that these two remodelers functionally cooperate to induce stress-responsive genes under proteotoxic conditions.
National Journal of Physiology, Pharmacy and Pharmacology, 2021
Background: Constructing blueprint for assessment is an important approach evolving today and bei... more Background: Constructing blueprint for assessment is an important approach evolving today and being emphasized to assess the medical students. It is necessary that the items in the question paper should match the course and a proportional weightage should be given to each competency of the curriculum with respect to its domain and clinical relevance. Aim and Objectives: The aim of the study was to prepare test blueprints for 2 nd year medical undergraduate syllabus of Pharmacology papers-Paper I and Paper II. Materials and Methods: This study was carried out in the Pharmacology Department of Geetanjali Medical College, Udaipur. All the competencies based on the knowledge domain of the 2 nd-year medical undergraduate curriculum for the Indian medical graduate were divided into two parts for theory paper I and paper II of pharmacology. Each competency or its subdivision was given pharmacological and clinical importance from score 1 to 3 and weightage was calculated for each competency. After devising both the blueprints, they were sent by email for validation by the peers and experts in the field of pharmacology. Results: Two final blueprints were prepared each for Papers I and II for summative theory assessment in pharmacology. General pharmacology carried the maximum weightage in Paper I which was found to be 30 marks out of 100 followed by 16 marks for central nervous system. In Paper II weightage of antimicrobial drugs was highest, that is, 35 marks followed by hormonal and related drugs which was 21 marks out of 100. Conclusion: Blueprints should be executed as an essential part of preparing the theory papers for all subjects. The blueprints should be periodically reviewed by the experts in the field and redesigned as per the changes in the curriculum.
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Papers by Sakshi Singh