Treatment of Hepatitis C virus (HCV) in patients with severe renal insufficiency is cumbersome as... more Treatment of Hepatitis C virus (HCV) in patients with severe renal insufficiency is cumbersome as sofosbuvir is mainly excreted by the kidneys. There is paucity of data on the use of sofosbuvir and NS5A inhibitors in these patients. We hereby report our experience of treating chronic hepatitis C in patients with severe renal insufficiency with full dose sofosbuvir and NS5A inhibitors.Forty-seven patients with severe renal insufficiency (on dialysis n=39, predialysis n=8) with HCV infection were treated between December 2015- August 2017 with full dose sofosbuvir with ledipasvir or daclatasvir for 12 /24 weeks depending on the genotype and presence or absence of cirrhosis. The distribution of HCV genotype was genotype 1 in 32(68.1%), genotype 3 in 13 (27.7%) and 4 in 2 (4.3%) patients. Among 12 (25.5%) patients with cirrhosis, 7 (14.9%) were decompensated with ascites. All patients had End of treatment response and sustained viral response at 12 weeks was achieved in 45 (95.7%) patie...
Portosystemic collaterals are common sequelae of portal hypertension. These often present as gast... more Portosystemic collaterals are common sequelae of portal hypertension. These often present as gastroesophageal varices. Ectopic varices can rarely be seen in duodenum, jejunum, rectum, and sites of surgical anastomoses. Bladder varices are extremely rare presenting with recurrent hematuria, with only a few reported cases. We report here management of an unusual case of hematuria managed with blood transfusion, intravenous terlipressin and endoscopic N-butyl cyanoacrylate glue injection.
Transactions of the Indian Institute of Metals, 2011
Abstract ZrN coatings were grown on silicon (100) substrate by reactive pulsed direct current spu... more Abstract ZrN coatings were grown on silicon (100) substrate by reactive pulsed direct current sputtering in a mixture of argon and nitrogen gases. The structural parameters and crystallite size as a function of substrate temperatures in the range 300873 K were studied using x-...
Information Technology and Mobile Communication, 2011
Abstract. A mobile adhoc network (MANET) is a network which does not have any centralized control... more Abstract. A mobile adhoc network (MANET) is a network which does not have any centralized control. Security and trust management are paramount concern for these networks for efficient data transfer among the participating nodes. In this paper, we propose an efficient ...
Treatment of Hepatitis C virus (HCV) in patients with severe renal insufficiency is cumbersome as... more Treatment of Hepatitis C virus (HCV) in patients with severe renal insufficiency is cumbersome as sofosbuvir is mainly excreted by the kidneys. There is paucity of data on the use of sofosbuvir and NS5A inhibitors in these patients. We hereby report our experience of treating chronic hepatitis C in patients with severe renal insufficiency with full dose sofosbuvir and NS5A inhibitors.Forty-seven patients with severe renal insufficiency (on dialysis n=39, predialysis n=8) with HCV infection were treated between December 2015- August 2017 with full dose sofosbuvir with ledipasvir or daclatasvir for 12 /24 weeks depending on the genotype and presence or absence of cirrhosis. The distribution of HCV genotype was genotype 1 in 32(68.1%), genotype 3 in 13 (27.7%) and 4 in 2 (4.3%) patients. Among 12 (25.5%) patients with cirrhosis, 7 (14.9%) were decompensated with ascites. All patients had End of treatment response and sustained viral response at 12 weeks was achieved in 45 (95.7%) patie...
Portosystemic collaterals are common sequelae of portal hypertension. These often present as gast... more Portosystemic collaterals are common sequelae of portal hypertension. These often present as gastroesophageal varices. Ectopic varices can rarely be seen in duodenum, jejunum, rectum, and sites of surgical anastomoses. Bladder varices are extremely rare presenting with recurrent hematuria, with only a few reported cases. We report here management of an unusual case of hematuria managed with blood transfusion, intravenous terlipressin and endoscopic N-butyl cyanoacrylate glue injection.
Transactions of the Indian Institute of Metals, 2011
Abstract ZrN coatings were grown on silicon (100) substrate by reactive pulsed direct current spu... more Abstract ZrN coatings were grown on silicon (100) substrate by reactive pulsed direct current sputtering in a mixture of argon and nitrogen gases. The structural parameters and crystallite size as a function of substrate temperatures in the range 300873 K were studied using x-...
Information Technology and Mobile Communication, 2011
Abstract. A mobile adhoc network (MANET) is a network which does not have any centralized control... more Abstract. A mobile adhoc network (MANET) is a network which does not have any centralized control. Security and trust management are paramount concern for these networks for efficient data transfer among the participating nodes. In this paper, we propose an efficient ...
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Papers by Monica Su