Background: Protein-protein interactions (PPI) can be classified according to their characteristi... more Background: Protein-protein interactions (PPI) can be classified according to their characteristics into, for example obligate or transient interactions. The identification and characterization of these PPI types may help in the functional annotation of new protein complexes and in the prediction of protein interaction partners by knowledge driven approaches.
The current Southwest drought is exceptional for its high temperatures and arguably the most seve... more The current Southwest drought is exceptional for its high temperatures and arguably the most severe in history. Coincidentally, there has been an increase in forest and woodland mortality due to fires and pathogenic outbreaks. Although the high temperatures and aridity are consistent with projected impacts of greenhouse warming, it is unclear whether the drought can be attributed to increased greenhouse gasses or is a product of natural climatic variability. Climate models indicate that the 21st century will be increasingly arid and droughts more severe and prolonged. Forest and woodland mortality due to fires and pathogens will increase. Demography and food security dictate that water demand in the Southwest will remain appreciable. If projected population growth is twinned with suburb-centered development, domestic demands will intensify. Meeting domestic demands through transference from agriculture presents concerns for rural sustainability and food security. Environmental concerns will limit additional transference from rivers. It is unlikely that traditional supply-side solutions such as more dams will securely meet demands at current per-capita levels. Significant savings in domestic usage can be realized through decreased applications of potable water to landscaping, but this is a small fraction of total regional water use, which is dominated by agriculture. Technical innovations, policy measures, and market-based solutions that increase supply and decrease water demand are all needed. Meeting 21st-century sustainability challenges in the Southwest will also require planning, cooperation, and integration that surpass 20th-century efforts in terms of geographic scope, jurisdictional breadth, multisectoral engagement, and the length of planning timelines.
Analysis of δ18Ocellulose, δ13Corganic matter, and δ13Ccellulose at about 100 year intervals from... more Analysis of δ18Ocellulose, δ13Corganic matter, and δ13Ccellulose at about 100 year intervals from organic matter deposited in Toronto Lake, Northwest Territories, Canada, revealed an 8000-year history of rapid, post-glacial hydrologic change at the treeline zone. Several mid-Holocene phases of enriched δ13Corg and δ13Ccell, caused by elevated lake productivity, declining [CO2(aq)], and closed basin conditions, were abruptly terminated by intervals of open hydrology recorded by sharply depleted δ18Ocell. Two of these events, at 5000 and 4500 BP, are correlated with increased total organic content and Picea mariana pollen concentration, which indicate that high levels of productivity were also accompanied by northern treeline advances. A third treeline advance at about 2500 BP is also marked by an apparent outflow event from Toronto Lake, but this was not associated with δ13Corg/cell enrichment in the sediment record because rapid and substantial lake water renewal probably prevented productivity-driven enrichment of the dissolved inorganic carbon and replenished the CO2(aq) supply to thriving phytoplankton. However, high sediment organic content during this period suggests increased productivity. Increases in the inflow:evaporation ratio at about 6500 and 3500 BP were also sufficient to cause Toronto Lake to overflow but the prevailing climate during these periods apparently did not favour appreciable northward treeline migration or changes in lake productivity.
Environmental isotopes and geochemical parameters were used to evaluate the sources and fate of n... more Environmental isotopes and geochemical parameters were used to evaluate the sources and fate of nitrate (NO− 3) and tetrachloroethene (PCE) in an alluvial contaminated aquifer. Isotope data and redox parameters data indicated that biodegradation does not play any role in the attenuation of these compounds along the groundwater flow system. Furthermore, nitrate isotopes and concentration data allowed the authors to distinguish two nitrate inputs and relate them to their possible sources. The primary source originates from septic waste and the secondary source is associated with nitrogenous fertilizer application. Regarding PCE, the δ13C values do not change for approximately 1000 m along the groundwater flow system despite large decreases of PCE concentration, thus confirming that physical processes do not alter the isotopic composition of organic compounds; this finding has a significant implication for the use of carbon isotope ratios for fingerprinting sources of PCE in VOC plumes. This study has shown that combined use of environmental isotopes and geochemical parameters is an efficient approach for water resource management studies in sites polluted by various types of contaminants.
La construcción de un personaje depende de una hábil caracterización, de nuestro conocimiento de ... more La construcción de un personaje depende de una hábil caracterización, de nuestro conocimiento de la vida y sus tipos humanos, de nuestro ojo penetrante y nuestra capacidad para tipos de fluidos, también llamados humores. Así, la sangre, la flema, la bilis amarilla y la bilis negra daban origen a cuatro temperamentos: Un exceso de sangre conducía al sanguíneo que desarrollaría una personalidad caracterizada como optimista, alegre, abierto, extravertido y de apariencia saludable y agradable. Una abundante cantidad de linfa define al flemático. Serían personas lentas, apáticas, siempre con tendencia a la inactividad motivada por el cansancio y la abulia. En tercer lugar tendríamos al colérico, definido por un exceso de bilis amarilla. Será una persona irascible, fuerte, agresiva por naturaleza, combativa e impulsiva. Finalmente, la excesiva EXCESO DE BILIS NEGRA: MELANCÓLICO EXCESO DE LINFA: FLEMÁTICO EXCESO DE SANGRE: SANGUÍNEO EXCESO DE BILIS AMARILLA: COLÉRICO Anthony: Someone comes in and moves the stuff.
En el presente artículo, se revisan las circunstancias particulares, autores e ideas que influyer... more En el presente artículo, se revisan las circunstancias particulares, autores e ideas que influyeron en la generación de uno de los modelos de personalidad más sólidos con que cuenta la Psicología hasta nuestros días: el Modelo Psicobiológico de Eysenck. Se presentan las características principales del mismo, las cuales lo definen como un modelo disposicional, dimensional, jerárquico y psicobiológico. El intento de mejorar la descripción, explicación y medición de las dimensiones llevó a este autor a proponer modificaciones a su teoría original y a sus instrumentos. Se analizan de este modo las distintas etapas de su modelo. A pesar de la proliferación de teorías de personalidad, el modelo de Eysenck tienen una validez empírica que pocos poseen. Disponemos en Psicología de la Personalidad de un cuerpo de conocimientos que representa el Paradigma dentro del cual con mucha probabilidad nos moveremos en los próximos años.
Independientemente de la complejidad de los datos disponibles y del procedimiento estadístico que... more Independientemente de la complejidad de los datos disponibles y del procedimiento estadístico que se tenga intención de utilizar, una exploración minuciosa de los datos previa al inicio de cualquier análisis posee importantes ventajas que un analista de datos no puede pasar por alto. Una exploración minuciosa de los datos permite identificar, entre otras cosas: posibles errores (datos mal introducidos, respuestas mal codificadas, etc.), valores extremos (valores que se alejan demasiado del resto), pautas extrañas en los datos (valores que se repiten demasiado o que no aparecen nunca, etc.), variabilidad no esperada (demasiados casos en una de las dos colas de la distribución, demasiada concentración en torno a determinado valor), etc. El procedimiento Explorar permite estudiar este tipo de problemas.
Background: Protein-protein interactions (PPI) can be classified according to their characteristi... more Background: Protein-protein interactions (PPI) can be classified according to their characteristics into, for example obligate or transient interactions. The identification and characterization of these PPI types may help in the functional annotation of new protein complexes and in the prediction of protein interaction partners by knowledge driven approaches.
The current Southwest drought is exceptional for its high temperatures and arguably the most seve... more The current Southwest drought is exceptional for its high temperatures and arguably the most severe in history. Coincidentally, there has been an increase in forest and woodland mortality due to fires and pathogenic outbreaks. Although the high temperatures and aridity are consistent with projected impacts of greenhouse warming, it is unclear whether the drought can be attributed to increased greenhouse gasses or is a product of natural climatic variability. Climate models indicate that the 21st century will be increasingly arid and droughts more severe and prolonged. Forest and woodland mortality due to fires and pathogens will increase. Demography and food security dictate that water demand in the Southwest will remain appreciable. If projected population growth is twinned with suburb-centered development, domestic demands will intensify. Meeting domestic demands through transference from agriculture presents concerns for rural sustainability and food security. Environmental concerns will limit additional transference from rivers. It is unlikely that traditional supply-side solutions such as more dams will securely meet demands at current per-capita levels. Significant savings in domestic usage can be realized through decreased applications of potable water to landscaping, but this is a small fraction of total regional water use, which is dominated by agriculture. Technical innovations, policy measures, and market-based solutions that increase supply and decrease water demand are all needed. Meeting 21st-century sustainability challenges in the Southwest will also require planning, cooperation, and integration that surpass 20th-century efforts in terms of geographic scope, jurisdictional breadth, multisectoral engagement, and the length of planning timelines.
Analysis of δ18Ocellulose, δ13Corganic matter, and δ13Ccellulose at about 100 year intervals from... more Analysis of δ18Ocellulose, δ13Corganic matter, and δ13Ccellulose at about 100 year intervals from organic matter deposited in Toronto Lake, Northwest Territories, Canada, revealed an 8000-year history of rapid, post-glacial hydrologic change at the treeline zone. Several mid-Holocene phases of enriched δ13Corg and δ13Ccell, caused by elevated lake productivity, declining [CO2(aq)], and closed basin conditions, were abruptly terminated by intervals of open hydrology recorded by sharply depleted δ18Ocell. Two of these events, at 5000 and 4500 BP, are correlated with increased total organic content and Picea mariana pollen concentration, which indicate that high levels of productivity were also accompanied by northern treeline advances. A third treeline advance at about 2500 BP is also marked by an apparent outflow event from Toronto Lake, but this was not associated with δ13Corg/cell enrichment in the sediment record because rapid and substantial lake water renewal probably prevented productivity-driven enrichment of the dissolved inorganic carbon and replenished the CO2(aq) supply to thriving phytoplankton. However, high sediment organic content during this period suggests increased productivity. Increases in the inflow:evaporation ratio at about 6500 and 3500 BP were also sufficient to cause Toronto Lake to overflow but the prevailing climate during these periods apparently did not favour appreciable northward treeline migration or changes in lake productivity.
Environmental isotopes and geochemical parameters were used to evaluate the sources and fate of n... more Environmental isotopes and geochemical parameters were used to evaluate the sources and fate of nitrate (NO− 3) and tetrachloroethene (PCE) in an alluvial contaminated aquifer. Isotope data and redox parameters data indicated that biodegradation does not play any role in the attenuation of these compounds along the groundwater flow system. Furthermore, nitrate isotopes and concentration data allowed the authors to distinguish two nitrate inputs and relate them to their possible sources. The primary source originates from septic waste and the secondary source is associated with nitrogenous fertilizer application. Regarding PCE, the δ13C values do not change for approximately 1000 m along the groundwater flow system despite large decreases of PCE concentration, thus confirming that physical processes do not alter the isotopic composition of organic compounds; this finding has a significant implication for the use of carbon isotope ratios for fingerprinting sources of PCE in VOC plumes. This study has shown that combined use of environmental isotopes and geochemical parameters is an efficient approach for water resource management studies in sites polluted by various types of contaminants.
La construcción de un personaje depende de una hábil caracterización, de nuestro conocimiento de ... more La construcción de un personaje depende de una hábil caracterización, de nuestro conocimiento de la vida y sus tipos humanos, de nuestro ojo penetrante y nuestra capacidad para tipos de fluidos, también llamados humores. Así, la sangre, la flema, la bilis amarilla y la bilis negra daban origen a cuatro temperamentos: Un exceso de sangre conducía al sanguíneo que desarrollaría una personalidad caracterizada como optimista, alegre, abierto, extravertido y de apariencia saludable y agradable. Una abundante cantidad de linfa define al flemático. Serían personas lentas, apáticas, siempre con tendencia a la inactividad motivada por el cansancio y la abulia. En tercer lugar tendríamos al colérico, definido por un exceso de bilis amarilla. Será una persona irascible, fuerte, agresiva por naturaleza, combativa e impulsiva. Finalmente, la excesiva EXCESO DE BILIS NEGRA: MELANCÓLICO EXCESO DE LINFA: FLEMÁTICO EXCESO DE SANGRE: SANGUÍNEO EXCESO DE BILIS AMARILLA: COLÉRICO Anthony: Someone comes in and moves the stuff.
En el presente artículo, se revisan las circunstancias particulares, autores e ideas que influyer... more En el presente artículo, se revisan las circunstancias particulares, autores e ideas que influyeron en la generación de uno de los modelos de personalidad más sólidos con que cuenta la Psicología hasta nuestros días: el Modelo Psicobiológico de Eysenck. Se presentan las características principales del mismo, las cuales lo definen como un modelo disposicional, dimensional, jerárquico y psicobiológico. El intento de mejorar la descripción, explicación y medición de las dimensiones llevó a este autor a proponer modificaciones a su teoría original y a sus instrumentos. Se analizan de este modo las distintas etapas de su modelo. A pesar de la proliferación de teorías de personalidad, el modelo de Eysenck tienen una validez empírica que pocos poseen. Disponemos en Psicología de la Personalidad de un cuerpo de conocimientos que representa el Paradigma dentro del cual con mucha probabilidad nos moveremos en los próximos años.
Independientemente de la complejidad de los datos disponibles y del procedimiento estadístico que... more Independientemente de la complejidad de los datos disponibles y del procedimiento estadístico que se tenga intención de utilizar, una exploración minuciosa de los datos previa al inicio de cualquier análisis posee importantes ventajas que un analista de datos no puede pasar por alto. Una exploración minuciosa de los datos permite identificar, entre otras cosas: posibles errores (datos mal introducidos, respuestas mal codificadas, etc.), valores extremos (valores que se alejan demasiado del resto), pautas extrañas en los datos (valores que se repiten demasiado o que no aparecen nunca, etc.), variabilidad no esperada (demasiados casos en una de las dos colas de la distribución, demasiada concentración en torno a determinado valor), etc. El procedimiento Explorar permite estudiar este tipo de problemas.
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