Gadofosveset

Gadofosveset trisodium

Systematic (IUPAC) name
Trisodium 2-{[(2R)-2-[bis(2-oxido-2-oxoethyl)amino]-3-[(4,4-diphenylcyclohexyl)oxy-oxidophosphoryl]oxypropyl]-[2-[bis(2-oxido-2-oxoethyl)amino]ethyl]amino}acetate
Clinical data
Trade names	Vasovist, Ablavar
Pregnancy category	US: C (Risk not ruled out)
Legal status	US: ℞-only
Routes of administration	Intravenous
Identifiers
CAS Number	193901-90-5
ATC code	V08CA11 (WHO)
PubChem	CID: 158440
DrugBank	DB06705
ChemSpider	139381
KEGG	D08005 Y
Chemical data
Formula	C33H40GdN3Na3O15P
Molecular mass	975.88 g/mol
SMILES [Gd+3].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)C[C@@H](N(CC([O-])=O)CC([O-])=O)COP([O-])(=O)OC3CCC(c1ccccc1)(c2ccccc2)CC3.O
InChI InChI=1S/C33H44N3O14P.Gd.3Na.H2O/c37-28(38)18-34(15-16-35(19-29(39)40)20-30(41)42)17-26(36(21-31(43)44)22-32(45)46)23-49-51(47,48)50-27-11-13-33(14-12-27,24-7-3-1-4-8-24)25-9-5-2-6-10-25;;;;;/h1-10,26-27H,11-23H2,(H,37,38)(H,39,40)(H,41,42)(H,43,44)(H,45,46)(H,47,48);;;;;1H2/q;+3;3*+1;/p-6/t26-;;;;;/m1...../s1 Key:PIZALBORPSCYJU-QSQMUHTISA-H

Gadofosveset (trade names Vasovist, Ablavar) is a gadolinium-based MRI contrast agent. It is used in form of the trisodium salt. It acts as a blood pool agent by binding to human serum albumin.