An entry from the Cambridge Structural Database, the world's repository for small molecule cr... more An entry from the Cambridge Structural Database, the world's repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
An entry from the Cambridge Structural Database, the world's repository for small molecule cr... more An entry from the Cambridge Structural Database, the world's repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
Facile Palladium Catalyzed Suzuki-Miyaura Coupling in Air and Water at Ambient Temperature.-A new... more Facile Palladium Catalyzed Suzuki-Miyaura Coupling in Air and Water at Ambient Temperature.-A new palladacyclic catalyst shows high activity in aqueous Suzuki-Miyaura coupling at room temperature. Using an optimized protocol a broad range of products (III) are synthesized in good to high yields and high purity by simple filtration.-(MARZIALE, A.
An entry from the Cambridge Structural Database, the world's repository for small molecule cr... more An entry from the Cambridge Structural Database, the world's repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
An entry from the Cambridge Structural Database, the world's repository for small molecule cr... more An entry from the Cambridge Structural Database, the world's repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
Nitric oxide (NO) is a key signaling molecule that regulates diverse biological processes in both... more Nitric oxide (NO) is a key signaling molecule that regulates diverse biological processes in both animals and plants, including important roles in male gamete physiology. In plants, NO is generated in pollen tubes (PTs) and affects intracellular responses through the modulation of Ca 2+ signaling, actin organization, vesicle trafficking and cell wall deposition, bearing consequences in pollen-stigma interactions and PT guidance. In contrast, the NO-responsive proteins that mediate these responses remain elusive. Here, we show that PTs of Arabidopsis thaliana mutants impaired in the pollenspecific DIACYLGLYCEROL KINASE4 (DGK4) grow slower and become partially insensitive to NO-dependent growth inhibition and reorientation responses. Recombinant DGK4 protein yields NO-responsive spectral and catalytic changes in vitro that are compatible with a role in NO perception and signaling in PTs. In addition to the expected phosphatidic acid-producing kinase activity, DGK4 recombinant protein also revealed guanylyl cyclase activity, as inferred by sequence analysis. Our results are compatible with a role for the fast-diffusible NO gas in signaling and cell-cell communication via the modulation of DGK4 activity during the progamic phase of angiosperm reproduction.
Journal of The Chemical Society-dalton Transactions, 1998
Rare-earth silylamides of type [Ln{N(SiHMe2)2}3(thf)x] (Ln = Sc, Y, La, Nd, Er or Lu) have been p... more Rare-earth silylamides of type [Ln{N(SiHMe2)2}3(thf)x] (Ln = Sc, Y, La, Nd, Er or Lu) have been prepared in high yield by reaction of 2.9 equivalents of Li[N(SiHMe2)2] with [LnCl3(thf)x] in n-hexane or thf, depending on the solubility of the rare-earth halide precursor. The complexes [Ln{N(SiHMe2)2}3(thf)2] (Ln = Y, La to Lu) are isostructural in the solid state, adopting the preferred (3 + 2, distorted) trigonal bipyramidal geometry, whilst [Sc{N(SiHMe2)2}3(thf)] has a distorted tetrahedral co-ordination geometry and short Sc· · ·Si contacts in the solid state. The reaction of [Y{N(SiHMe2)2}3(thf)2] with varying amounts of AlMe3 resulted in desolvation and alkylation with formation of AlMe3(thf), {AlMe2[µ-N(SiHMe2]2}2 and heterobimetallic (Y/Al) species. The generation of surface-bonded ‘(SiO)xY[N(SiHMe2)2]y’ and ‘SiOSiHMe2’ moieties via the grafting of [Y{N(SiHMe2)2}3(thf)2] onto the mesoporous silicate MCM-41 is described in detail. Consideration is given to the factors governing the siloxide formation and silylation reactions, and the thermal stability of the surface species.
Publisher: Elsevier NOTICE: this is the author's version of a work that was accepted for publicat... more Publisher: Elsevier NOTICE: this is the author's version of a work that was accepted for publication in Applied Materials Today. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Applied Materials Today, [5, (2016)]
Molybdenum-Catalyzed Olefin Epoxidation: Ligand Effects.-The electronic influence of ligands such... more Molybdenum-Catalyzed Olefin Epoxidation: Ligand Effects.-The electronic influence of ligands such as (I) in molybdenum oxobisperoxo complexes on the activity of such epoxidation catalyst is investigated with a combination of spectroscopic, computational and kinetic methods. On the basis of the results, rules for the ligand design of epoxidation catalyst can be established. A mechanism is supported in which the peroxo complex activates the oxidizing agent instead of directly transferring an oxygen atom from an η2-peroxo ligand to the olefin.-(
An entry from the Cambridge Structural Database, the world's repository for small molecule cr... more An entry from the Cambridge Structural Database, the world's repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
An entry from the Cambridge Structural Database, the world's repository for small molecule cr... more An entry from the Cambridge Structural Database, the world's repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
Facile Palladium Catalyzed Suzuki-Miyaura Coupling in Air and Water at Ambient Temperature.-A new... more Facile Palladium Catalyzed Suzuki-Miyaura Coupling in Air and Water at Ambient Temperature.-A new palladacyclic catalyst shows high activity in aqueous Suzuki-Miyaura coupling at room temperature. Using an optimized protocol a broad range of products (III) are synthesized in good to high yields and high purity by simple filtration.-(MARZIALE, A.
An entry from the Cambridge Structural Database, the world's repository for small molecule cr... more An entry from the Cambridge Structural Database, the world's repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
An entry from the Cambridge Structural Database, the world's repository for small molecule cr... more An entry from the Cambridge Structural Database, the world's repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
Nitric oxide (NO) is a key signaling molecule that regulates diverse biological processes in both... more Nitric oxide (NO) is a key signaling molecule that regulates diverse biological processes in both animals and plants, including important roles in male gamete physiology. In plants, NO is generated in pollen tubes (PTs) and affects intracellular responses through the modulation of Ca 2+ signaling, actin organization, vesicle trafficking and cell wall deposition, bearing consequences in pollen-stigma interactions and PT guidance. In contrast, the NO-responsive proteins that mediate these responses remain elusive. Here, we show that PTs of Arabidopsis thaliana mutants impaired in the pollenspecific DIACYLGLYCEROL KINASE4 (DGK4) grow slower and become partially insensitive to NO-dependent growth inhibition and reorientation responses. Recombinant DGK4 protein yields NO-responsive spectral and catalytic changes in vitro that are compatible with a role in NO perception and signaling in PTs. In addition to the expected phosphatidic acid-producing kinase activity, DGK4 recombinant protein also revealed guanylyl cyclase activity, as inferred by sequence analysis. Our results are compatible with a role for the fast-diffusible NO gas in signaling and cell-cell communication via the modulation of DGK4 activity during the progamic phase of angiosperm reproduction.
Journal of The Chemical Society-dalton Transactions, 1998
Rare-earth silylamides of type [Ln{N(SiHMe2)2}3(thf)x] (Ln = Sc, Y, La, Nd, Er or Lu) have been p... more Rare-earth silylamides of type [Ln{N(SiHMe2)2}3(thf)x] (Ln = Sc, Y, La, Nd, Er or Lu) have been prepared in high yield by reaction of 2.9 equivalents of Li[N(SiHMe2)2] with [LnCl3(thf)x] in n-hexane or thf, depending on the solubility of the rare-earth halide precursor. The complexes [Ln{N(SiHMe2)2}3(thf)2] (Ln = Y, La to Lu) are isostructural in the solid state, adopting the preferred (3 + 2, distorted) trigonal bipyramidal geometry, whilst [Sc{N(SiHMe2)2}3(thf)] has a distorted tetrahedral co-ordination geometry and short Sc· · ·Si contacts in the solid state. The reaction of [Y{N(SiHMe2)2}3(thf)2] with varying amounts of AlMe3 resulted in desolvation and alkylation with formation of AlMe3(thf), {AlMe2[µ-N(SiHMe2]2}2 and heterobimetallic (Y/Al) species. The generation of surface-bonded ‘(SiO)xY[N(SiHMe2)2]y’ and ‘SiOSiHMe2’ moieties via the grafting of [Y{N(SiHMe2)2}3(thf)2] onto the mesoporous silicate MCM-41 is described in detail. Consideration is given to the factors governing the siloxide formation and silylation reactions, and the thermal stability of the surface species.
Publisher: Elsevier NOTICE: this is the author's version of a work that was accepted for publicat... more Publisher: Elsevier NOTICE: this is the author's version of a work that was accepted for publication in Applied Materials Today. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Applied Materials Today, [5, (2016)]
Molybdenum-Catalyzed Olefin Epoxidation: Ligand Effects.-The electronic influence of ligands such... more Molybdenum-Catalyzed Olefin Epoxidation: Ligand Effects.-The electronic influence of ligands such as (I) in molybdenum oxobisperoxo complexes on the activity of such epoxidation catalyst is investigated with a combination of spectroscopic, computational and kinetic methods. On the basis of the results, rules for the ligand design of epoxidation catalyst can be established. A mechanism is supported in which the peroxo complex activates the oxidizing agent instead of directly transferring an oxygen atom from an η2-peroxo ligand to the olefin.-(
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