Papers by Anisha J.Perumbilly
International journal of advanced biochemistry research, 2024
Vitamin D, one of the fat-soluble vitamins, has a crucial role in mineral metabolism, immunomodul... more Vitamin D, one of the fat-soluble vitamins, has a crucial role in mineral metabolism, immunomodulation and as an antioxidant. Clinical conditions of osteoarthritis, gastrointestinal diseases, and skin and ocular pathologies are the commonly encountered problems in captive Asian elephants (Elephas maximus). Most of these conditions are suspected to arise from deficiency of vitamin D. Still it's metabolism in elephants is not clearly understood and a reference interval for it has not yet been established, limiting the prompt diagnosis and treatment of diseases in these animals. An immunoassay-based quantitative determination of total 25-hydroxyvitamin D (25(OH)D) was carried out in blood samples received from apparently healthy elephants at Centralised Clinical Laboratory, VCC, VCRI, Tirunelveli. The samples submitted as a part of the general health checkup of animals from a period of September 2022 to August 2023 were selected for the study. The mean value of 25(OH)D estimated in ten adult female Asian elephants in captivity is 11.15±1.98 ng/mL. This information obtained from this preliminary study expands the knowledge about this analyte and helps in assessing and establishing the reference interval for vitamin D status in captive elephants.
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Vitamin D, one of the fat-soluble vitamins, has a crucial role in mineral metabolism, immunomodul... more Vitamin D, one of the fat-soluble vitamins, has a crucial role in mineral metabolism, immunomodulation and as an antioxidant. Clinical conditions of osteoarthritis, gastrointestinal diseases, and skin and ocular pathologies are the commonly encountered problems in captive Asian elephants (Elephas maximus). Most of these conditions are suspected to arise from deficiency of vitamin D. Still it's metabolism in elephants is not clearly understood and a reference interval for it has not yet been established, limiting the prompt diagnosis and treatment of diseases in these animals. An immunoassay-based quantitative determination of total 25-hydroxyvitamin D (25(OH)D) was carried out in blood samples received from apparently healthy elephants at Centralised Clinical Laboratory, VCC, VCRI, Tirunelveli. The samples submitted as a part of the general health checkup of animals from a period of September 2022 to August 2023 were selected for the study. The mean value of 25(OH)D estimated in ten adult female Asian elephants in captivity is 11.15±1.98 ng/mL. This information obtained from this preliminary study expands the knowledge about this analyte and helps in assessing and establishing the reference interval for vitamin D status in captive elephants.
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The concentrations of glucose, non esterified fatty acids (NEFA), β-hydroxybutyrate (BHB), choles... more The concentrations of glucose, non esterified fatty acids (NEFA), β-hydroxybutyrate (BHB), cholesterol, malondialdehyde (MDA) and total antioxidant status (TAS) of 15 healthy crossbred dairy cows maintained under identical conditions in a farm, and fed on standard ration, during transition period were evaluated and compared with that of pre-transition and post-transition periods. The mean concentration of glucose (47.35±1.32 mg/dL) and cholesterol (95.83± 3.62 mg/dL) during transition period was significantly lower than pre and post-transition period. NEFA (0.576 ± 0.08 mmol/L) reported significant increase during transition. The mean concentration of BHB (0.638 ± 0.05 mmol/L) was significantly higher during transition period and the increase was persistent towards post-transition period. The level of MDA, an indicator of oxidative stress was higher during transition period (7.89 ± 1.16mmol/ml), indicating increased rate of lipid peroxidation during the period, whereas TAS did not s...
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Papers by Anisha J.Perumbilly