Genome Biology

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Featured article: Improved detection of methylation in ancient DNA

Featured article: APC mutations dysregulate alternative polyadenylation in cancer

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Non-human primates population genetics - Open until: 26 May 2025

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Epistasis - Open until: 21 May 2025

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Centromere structure and evolution - Open until: 8 Jan 2025

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Transposable elements in genome evolution - Open until: 21 Dec 2024

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Subcellular compartmentalization - Open until: 4 Dec 2024

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Articles

Genetic-by-age interaction analyses on complex traits in UK Biobank and their potential to identify effects on longitudinal trait change

Authors: Thomas W. Winkler, Simon Wiegrebe, Janina M. Herold, Klaus J. Stark, Helmut Küchenhoff and Iris M. Heid

Content type: Research 28 November 2024
Hierarchical annotation of eQTLs by H-eQTL enables identification of genes with cell type-divergent regulation

Authors: Pawel F. Przytycki and Katherine S. Pollard

Content type: Method 25 November 2024
scStateDynamics: deciphering the drug-responsive tumor cell state dynamics by modeling single-cell level expression changes

Authors: Wenbo Guo, Xinqi Li, Dongfang Wang, Nan Yan, Qifan Hu, Fan Yang, Xuegong Zhang, Jianhua Yao and Jin Gu

Content type: Method 21 November 2024
The genomic portrait of the Picene culture provides new insights into the Italic Iron Age and the legacy of the Roman Empire in Central Italy

Authors: Francesco Ravasini, Helja Kabral, Anu Solnik, Luciana de Gennaro, Francesco Montinaro, Ruoyun Hui, Chiara Delpino, Stefano Finocchi, Pierluigi Giroldini, Oscar Mei, Michael Allen Beck De Lotto, Elisabetta Cilli, Mogge Hajiesmaeil, Letizia Pistacchia, Flavia Risi, Chiara Giacometti…

Content type: Research 21 November 2024
Considerations in the search for epistasis

Authors: Marleen Balvert, Johnathan Cooper-Knock, Julian Stamp, Ross P. Byrne, Soufiane Mourragui, Juami van Gils, Stefania Benonisdottir, Johannes Schlüter, Kevin Kenna, Sanne Abeln, Alfredo Iacoangeli, Joséphine T. Daub, Brian L. Browning, Gizem Taş, Jiajing Hu, Yan Wang…

Content type: Review 19 November 2024

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A survey of best practices for RNA-seq data analysis

Authors: Ana Conesa, Pedro Madrigal, Sonia Tarazona, David Gomez-Cabrero, Alejandra Cervera, Andrew McPherson, Michał Wojciech Szcześniak, Daniel J. Gaffney, Laura L. Elo, Xuegong Zhang and Ali Mortazavi

Content type: Review 26 January 2016

The Erratum to this article has been published in Genome Biology 2016 17:181
Differential expression analysis for sequence count data

Authors: Simon Anders and Wolfgang Huber

Content type: Method 27 October 2010
The Kardashian index: a measure of discrepant social media profile for scientists

Authors: Neil Hall

Content type: Comment 30 July 2014
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Authors: Michael I Love, Wolfgang Huber and Simon Anders

Content type: METHOD 5 December 2014
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Authors: Jo Vandesompele, Katleen De Preter, Filip Pattyn, Bruce Poppe, Nadine Van Roy, Anne De Paepe and Frank Speleman

Content type: Research 18 June 2002

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Latest articles from Genome Medicine

Focus: Fertility

Read the latest papers on fertility across BMC flagship journals.

Cisplatin and carboplatin result in similar gonadotoxicity in immature human testis with implications for fertility preservation in childhood cancer
Melissa D. Tharmalingam et al.

Published in BMC Medicine 04 December 2020

Large-scale discovery of male reproductive tract-specific genes through analysis of RNA-seq datasets
Matthew Robertson et al.

Published in BMC Biology 19 August 2020

DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies
Florianne Vehmeijer et al.

Published in Genome Medicine 25 November 2020

The Tug1 lncRNA locus is essential for male fertility
Jordan Lewandowski et al.

Published in Genome Biology 07 September 2020

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Reviewer Acknowledgements 2020

The Editors and staff of Genome Biology would like to warmly thank the Reviewers whose comments helped to shape the journal, for their invaluable assistance with review of manuscripts in 2020.

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Genome Biology

Featured Articles

Featured article: Improved detection of methylation in ancient DNA

Featured article: APC mutations dysregulate alternative polyadenylation in cancer

Latest Collections Open for Submissions

Articles

Genetic-by-age interaction analyses on complex traits in UK Biobank and their potential to identify effects on longitudinal trait change

Hierarchical annotation of eQTLs by H-eQTL enables identification of genes with cell type-divergent regulation

scStateDynamics: deciphering the drug-responsive tumor cell state dynamics by modeling single-cell level expression changes

The genomic portrait of the Picene culture provides new insights into the Italic Iron Age and the legacy of the Roman Empire in Central Italy

Considerations in the search for epistasis

A survey of best practices for RNA-seq data analysis

Differential expression analysis for sequence count data

The Kardashian index: a measure of discrepant social media profile for scientists

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Latest articles from Genome Medicine

Genome-aware annotation of CRISPR guides validates targets in variant cell lines and enhances discovery in screens

Integrated analyses of multi-omic data derived from paired primary lung cancer and brain metastasis reveal the metabolic vulnerability as a novel therapeutic target

Genomic surveillance of multidrug-resistant organisms based on long-read sequencing

Focus: Fertility

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