(Q21123035)

English

NDUFA4 mitochondrial complex associated

mammalian protein found in Homo sapiens

cytochrome c oxidase subunit NDUFA4
complex I-MLRQ
NDUFA4
cytochrome c oxidase subunit FA4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4
Complex I 9kDa subunit
NADH-ubiquinone oxidoreductase MLRQ subunit
CI-MLRQ
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa

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Statements

1 reference

13 November 2019

NADH-ubiquinone reductase complex 1 MLRQ subunit

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O00483

1 reference

13 November 2019

1 reference

13 November 2019

NADH dehydrogenase (ubiquinone) activity

determination method or standard

NAS

TAS

cytochrome-c oxidase activity

determination method or standard

IMP

1 reference

retrieved

24 April 2018

stated in

NDUFA4 is a subunit of complex IV of the mammalian electron transport chain

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00483&geneProductId=UniProtKB:O00483

determination method or standard

IMP

protein binding

determination method or standard

IPI

1 reference

retrieved

8 April 2019

stated in

DJ-1 binds to mitochondrial complex I and maintains its activity

GOA

curator

Parkinsons Disease Gene Ontology Initiative

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00483

determination method or standard

IPI

protein-containing complex binding

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00483

determination method or standard

IDA

cell component

mitochondrial respiratory chain complex I

determination method or standard

3 references

8 April 2019

cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00483

determination method or standard

NAS

retrieved

8 April 2019

stated in

The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00483

determination method or standard

IDA

retrieved

8 April 2019

stated in

NDUFA4 is a subunit of complex IV of the mammalian electron transport chain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00483

determination method or standard

IDA

respirasome

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00483

determination method or standard

IEA

membrane

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00483

determination method or standard

IEA

mitochondrial respiratory chain complex IV

determination method or standard

3 references

8 April 2019

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00483

determination method or standard

IEA

retrieved

8 April 2019

stated in

NDUFA4 is a subunit of complex IV of the mammalian electron transport chain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00483

determination method or standard

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00483

determination method or standard

IBA

biological process

mitochondrial electron transport, NADH to ubiquinone

determination method or standard

NAS

1 reference

retrieved

8 April 2019

stated in

cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00483

determination method or standard

NAS

proton transmembrane transport

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00483

determination method or standard

IEA

mitochondrial electron transport, cytochrome c to oxygen

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00483

determination method or standard

TAS

physically interacts with

metformin

object of statement has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL1431

metformin hydrochloride

object of statement has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL1703

Identifiers

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

10 November 2015

http://www.uniprot.org/uniprot/Q62425.txt?version=128

1 reference

10 November 2015

http://www.uniprot.org/uniprot/Q62425.txt?version=128

1 reference

10 November 2015

http://www.uniprot.org/uniprot/Q62425.txt?version=128

1 reference

10 November 2015

http://www.uniprot.org/uniprot/Q62425.txt?version=128

(Q21123035)

NDUFA4 mitochondrial complex associated

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