(Q30442047)

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Degraded collagen fragments promote rapid disassembly of smooth muscle focal adhesions that correlates with cleavage of pp125(FAK), paxillin, and talin

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10545505%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Degraded collagen fragments promote rapid disassembly of smooth muscle focal adhesions that correlates with cleavage of pp125(FAK), paxillin, and talin (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10545505%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Neil O Carragher

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10545505%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

author name string

B Levkau

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10545505%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

R Ross

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10545505%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

E W Raines

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10545505%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

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1 November 1999

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Europe PubMed Central

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1 November 2019

Journal of Cell Biology

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10545505%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

147

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10545505%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10545505%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

619-630

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10545505%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Caspase-mediated cleavage of focal adhesion kinase pp125FAK and disassembly of focal adhesions in human endothelial cell apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Role of focal adhesion kinase in integrin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Cleavage of focal adhesion kinase by caspases during apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Regulation of Tenascin-C, a Vascular Smooth Muscle Cell Survival Factor that Interacts with the αvβ3 Integrin to Promote Epidermal Growth Factor Receptor Phosphorylation and Growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Induction and Repression of Collagenase-1 by Keratinocytes Is Controlled by Distinct Components of Different Extracellular Matrix Compartments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Induction of Cell Migration by Matrix Metalloprotease-2 Cleavage of Laminin-5

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Calpain: a cytosolic proteinase active at the membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Signaling through focal adhesion kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Complexes of focal adhesion kinase (FAK) and Crk-associated substrate (p130(Cas)) are elevated in cytoskeleton-associated fractions following adhesion and Src transformation. Requirements for Src kinase activity and FAK proline-rich motifs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Focal adhesions, contractility, and signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Osteopontin N-terminal domain contains a cryptic adhesive sequence recognized by alpha9beta1 integrin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Targeted proteolysis of the focal adhesion kinase pp125 FAK during c-MYC-induced apoptosis is suppressed by integrin signalling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

A mechanism for regulation of the adhesion-associated proteintyrosine kinase pp125FAK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Association of phosphatidylinositol 3-kinase, via the SH2 domains of p85, with focal adhesion kinase in polyoma middle t-transformed fibroblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Adhesion in cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Evidence that activation of platelet calpain is induced as a consequence of binding of adhesive ligand to the integrin, glycoprotein IIb-IIIa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Autonomous expression of a noncatalytic domain of the focal adhesion-associated protein tyrosine kinase pp125FAK

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Integrin cytoplasmic domains: mediators of cytoskeletal linkages and extra- and intracellular initiated transmembrane signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Insulin-like growth factor-I and platelet-derived growth factor-BB induce directed migration of human arterial smooth muscle cells via signaling pathways that are distinct from those of proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Dynamic expression of alpha 1 beta 1 and alpha 2 beta 1 integrin receptors by human vascular smooth muscle cells. Alpha 2 beta 1 integrin is required for chemotaxis across type I collagen-coated membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

v-Src-induced degradation of focal adhesion kinase during morphological transformation of chicken embryo fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Interaction of focal adhesion kinase with cytoskeletal protein talin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Altered distributions of the cytoskeletal proteins vinculin and alpha-actinin in cultured fibroblasts transformed by Rous sarcoma virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Platelet-derived growth factor-induced alterations in vinculin and actin distribution in BALB/c-3T3 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Collagens in atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Focal adhesions: transmembrane junctions between the extracellular matrix and the cytoskeleton

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Colocalization of calcium-dependent protease II and one of its substrates at sites of cell adhesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Extracellular matrix, cell skeletons, and embryonic development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Regulation of differentiated properties and proliferation of arterial smooth muscle cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Multiple elevations of cytosolic-free Ca2+ in human neutrophils: initiation by adherence receptors of the integrin family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Integrins: versatility, modulation, and signaling in cell adhesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Affinity of integrins for damaged extracellular matrix: alpha v beta 3 binds to denatured collagen type I through RGD sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Focal adhesion kinase (p125FAK): a point of convergence in the action of neuropeptides, integrins, and oncogenes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

20 June 2018

Matrix metalloproteinase-2 is an interstitial collagenase. Inhibitor-free enzyme catalyzes the cleavage of collagen fibrils and soluble native type I collagen generating the specific 3/4- and 1/4-length fragments

1 reference

https://api.crossref.org/works/10.1083%2FJCB.147.3.619

21 January 2018

Focal adhesion kinase (pp125FAK) cleavage and regulation by calpain

1 reference

https://api.crossref.org/works/10.1083%2FJCB.147.3.619

21 January 2018

Regulation of Cell Migration by the Calcium-dependent Protease Calpain

1 reference

https://api.crossref.org/works/10.1083%2FJCB.147.3.619

21 January 2018

Unphosphorylated and tyrosine-phosphorylated forms of a focal adhesion protein, paxillin, are substrates for calpain II in vitro: implications for the possible involvement of calpain II in mitosis-specific degradation of paxillin.

1 reference

https://api.crossref.org/works/10.1083%2FJCB.147.3.619

21 January 2018

Effects of collagenase-cleavage of type I collagen on alpha2beta1 integrin-mediated cell adhesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151179

26 November 2018

pp125FAK tyrosine kinase activity is not required for the assembly of F-actin stress fibres and focal adhesions in cultured mouse aortic smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10545505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic cleavage of alpha-actinin by calpain in T cells stimulated with anti-CD3 monoclonal antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/10545505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of calpain in integrin-mediated signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/10545505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell migration promoted by a potent GRGDS-containing thrombin-cleavage fragment of osteopontin

1 reference

https://pubmed.ncbi.nlm.nih.gov/10545505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fibrillar collagen inhibits arterial smooth muscle proliferation through regulation of Cdk2 inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10545505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calpain cleavage of focal adhesion proteins regulates the cytoskeletal attachment of integrin alphaIIbbeta3 (platelet glycoprotein IIb/IIIa) and the cellular retraction of fibrin clots

1 reference

https://pubmed.ncbi.nlm.nih.gov/10545505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenovirus-mediated gene transfer of the human tissue inhibitor of metalloproteinase-2 blocks vascular smooth muscle cell invasiveness in vitro and modulates neointimal development in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/10545505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Degradation of actin and vimentin by calpain II, a Ca2+‐dependent cysteine proteinase, in bovine lens

1 reference

https://pubmed.ncbi.nlm.nih.gov/10545505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification of human platelet-derived growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10545505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Properties of radiolabeled type I, II, and III collagens related to their use as substrates in collagenase assays

1 reference

https://pubmed.ncbi.nlm.nih.gov/10545505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

pp60src is an endogenous substrate for calpain in human blood platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/10545505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Migration of cultured vascular smooth muscle cells through a basement membrane barrier requires type IV collagenase activity and is inhibited by cellular differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10545505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Smooth muscle cell migration and matrix metalloproteinase expression after arterial injury in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/10545505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adhesion receptor activation of phosphatidylinositol 3-kinase. von Willebrand factor stimulates the cytoskeletal association and activation of phosphatidylinositol 3-kinase and pp60c-src in human platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/10545505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Receptors on platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/10545505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrin alpha 2 beta 1 is a positive regulator of collagenase (MMP-1) and collagen alpha 1(I) gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/10545505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1083/JCB.147.3.619

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10545505%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

release_g4tq3hql4rg33oila3y7nsqqpm

1 reference

https://api.fatcat.wiki/v0/release/g4tq3hql4rg33oila3y7nsqqpm

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10545505%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10545505%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

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