(Q33540073)

27 July 2017

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title

The oncogenic activation of beta-catenin (English)

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27 July 2017

Polakis P

1

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27 July 2017

publication date

1 February 1999

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Current Opinion in Genetics & Development

27 July 2017

published in

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27 July 2017

volume

9

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27 July 2017

issue

1

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27 July 2017

page(s)

15-21

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Cell adhesion and signal transduction: the Armadillo connection

27 July 2017

cites work

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7 January 2021

Drosophila wingless: a paradigm for the function and mechanism of Wnt signaling

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7 January 2021

Signal transduction of beta-catenin

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7 January 2021

Binding to cadherins antagonizes the signaling activity of beta-catenin during axis formation in Xenopus

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7 January 2021

Uncoupling cadherin-based adhesion from wingless signalling in Drosophila.

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7 January 2021

An in vivo structure-function study of armadillo, the beta-catenin homologue, reveals both separate and overlapping regions of the protein required for cell adhesion and for wingless signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3

7 January 2021

Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome

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7 January 2021

Association of the APC gene product with beta-catenin

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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3

7 January 2021

Association of the APC tumor suppressor protein with catenins

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7 January 2021

Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein

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7 January 2021

Wnt-1 modulates cell-cell adhesion in mammalian cells by stabilizing beta-catenin binding to the cell adhesion protein cadherin

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7 January 2021

Stabilization of beta-catenin by genetic defects in melanoma cell lines

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7 January 2021

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

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7 January 2021

Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene

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7 January 2021

Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

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7 January 2021

Attenuated familial adenomatous polyposis due to a mutation in the 3' part of the APC gene. A clue for understanding the function of the APC protein

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7 January 2021

Familial infiltrative fibromatosis (desmoid tumours) (MIM135290) caused by a recurrent 3' APC gene mutation.

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7 January 2021

A Drosophila homolog of the tumor suppressor gene adenomatous polyposis coli down-regulates beta-catenin but its zygotic expression is not essential for the regulation of Armadillo

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7 January 2021

Adenomatous polyposis coli tumor suppressor protein has signaling activity in Xenopus laevis embryos resulting in the induction of an ectopic dorsoanterior axis

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7 January 2021

Regulation of armadillo by a Drosophila APC inhibits neuronal apoptosis during retinal development

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7 January 2021

NH2-terminal deletion of beta-catenin results in stable colocalization of mutant beta-catenin with adenomatous polyposis coli protein and altered MDCK cell adhesion

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7 January 2021

Deletion of an amino-terminal sequence beta-catenin in vivo and promotes hyperphosporylation of the adenomatous polyposis coli tumor suppressor protein

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7 January 2021

A mutated beta-catenin gene encodes a melanoma-specific antigen recognized by tumor infiltrating lymphocytes

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7 January 2021

Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas

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7 January 2021

Expression and hormone regulation of Wnt2, 3, 4, 5a, 7a, 7b and 10b in normal human endometrium and endometrial carcinoma

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7 January 2021

Wnt-10b directs hypermorphic development and transformation in mammary glands of male and female mice

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7 January 2021

A novel human Wnt gene, WNT10B, maps to 12q13 and is expressed in human breast carcinomas

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7 January 2021

A novel frizzled gene identified in human esophageal carcinoma mediates APC/beta-catenin signals

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7 January 2021

Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer

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7 January 2021

Frzb, a secreted protein expressed in the Spemann organizer, binds and inhibits Wnt-8.

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7 January 2021

The cysteine-rich frizzled domain of Frzb-1 is required and sufficient for modulation of Wnt signaling

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7 January 2021

SARPs: A family of secreted apoptosis-related proteins

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7 January 2021

Activating Smoothened mutations in sporadic basal-cell carcinoma

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7 January 2021

Hedgehog signaling regulates transcription through Gli/Ci binding sites in the wingless enhancer

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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3

7 January 2021

The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3

7 January 2021

Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3

7 January 2021

Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of beta-catenin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3

7 January 2021

Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

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7 January 2021

Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and beta-catenin.

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7 January 2021

Bridging of β-catenin and glycogen synthase kinase-3β by Axin and inhibition of β-catenin-mediated transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3

7 January 2021

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta -catenin and promotes GSK-3beta -dependent phosphorylation of beta -catenin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3

7 January 2021

Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis

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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3

7 January 2021

Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3

7 January 2021

From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3

7 January 2021

Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3

7 January 2021

beta-Catenin associates with the actin-bundling protein fascin in a noncadherin complex

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3

7 January 2021

XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3

7 January 2021

Functional interaction of beta-catenin with the transcription factor LEF-1

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3

7 January 2021

Interaction of the DF3/MUC1 breast carcinoma-associated antigen and beta-catenin in cell adhesion

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3

7 January 2021

The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3

7 January 2021

Cellular Redistribution of Protein Tyrosine Phosphatases LAR and PTPσ by Inducible Proteolytic Processing

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3

7 January 2021

Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin- mediated cell-cell adhesion

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3

7 January 2021

Identification of c-MYC as a target of the APC pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3

7 January 2021

10.1016/S0959-437X(99)80003-3

Identifiers

DOI

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27 July 2017

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