(Q35678324)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14991001%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

review article

1 reference

title

Nucleocytoplasmic shuttling of signal transducers (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14991001%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14991001%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

author name string

Lan Xu

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14991001%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

publication date

1 March 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14991001%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Molecular Cell Biology

24 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14991001%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14991001%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14991001%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

page(s)

209-219

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14991001%20AND%20SRC:MED&resulttype=core&format=json

Signaling--2000 and beyond

24 November 2019

cites work

1 reference

Nuclear protein import using digitonin-permeabilized cells

31 March 2020

1 reference

Intramolecular masking of the nuclear location signal and dimerization domain in the precursor for the p50 NF-kappa B subunit

31 March 2020

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Intramolecular masking of nuclear import signal on NF-AT4 by casein kinase I and MEKK1

31 March 2020

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I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention

31 March 2020

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Nuclear localization signal-independent and importin/karyopherin-independent nuclear import of beta-catenin

31 March 2020

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ERK2 enters the nucleus by a carrier-independent mechanism

31 March 2020

1 reference

Evidence for existence of a nuclear pore complex-mediated, cytosol-independent pathway of nuclear translocation of ERK MAP kinase in permeabilized cells

31 March 2020

1 reference

beta-catenin can be transported into the nucleus in a Ran-unassisted manner

31 March 2020

1 reference

The nuclear import function of Smad2 is masked by SARA and unmasked by TGFbeta-dependent phosphorylation.

31 March 2020

1 reference

Regulating access to the genome: nucleocytoplasmic transport throughout the cell cycle

31 March 2020

1 reference

Nuclear targeting signal recognition: a key control point in nuclear transport?

31 March 2020

1 reference

The nuclear pore complex: nucleocytoplasmic transport and beyond

31 March 2020

1 reference

31 March 2020

Peering through the Pore

1 reference

The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus

31 March 2020

1 reference

alpha- and beta-forms of the 65-kDa subunit of protein phosphatase 2A have a similar 39 amino acid repeating structure

31 March 2020

1 reference

HEAT repeats in the Huntington's disease protein

31 March 2020

1 reference

Molecular cloning and sequence of cDNA encoding polyoma medium tumor antigen-associated 61-kDa protein

31 March 2020

1 reference

Structural view of the Ran-Importin beta interaction at 2.3 A resolution

31 March 2020

1 reference

Structure of importin-beta bound to the IBB domain of importin-alpha

31 March 2020

1 reference

Structural basis for the interaction between FxFG nucleoporin repeats and importin-beta in nuclear trafficking

31 March 2020

1 reference

Importin beta contains a COOH-terminal nucleoporin binding region important for nuclear transport

31 March 2020

1 reference

Translocation of β-catenin into the nucleus independent of interactions with FG-rich nucleoporins

31 March 2020

1 reference

Distinct domain utilization by Smad3 and Smad4 for nucleoporin interaction and nuclear import.

31 March 2020

1 reference

Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFbeta signaling complexes in the cytoplasm and nucleus

31 March 2020

1 reference

Isolation of a protein that is essential for the first step of nuclear protein import

31 March 2020

1 reference

Identification of cytosolic factors required for nuclear location sequence-mediated binding to the nuclear envelope

31 March 2020

1 reference

A novel receptor-mediated nuclear protein import pathway

31 March 2020

1 reference

A repeating amino acid motif shared by proteins with diverse cellular roles

31 March 2020

1 reference

Embryonic axis induction by the armadillo repeat domain of beta-catenin: evidence for intracellular signaling

31 March 2020

1 reference

Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor

31 March 2020

1 reference

Structural basis for the interaction between NTF2 and nucleoporin FxFG repeats

31 March 2020

1 reference

Structural basis of Smad2 recognition by the Smad anchor for receptor activation

31 March 2020

1 reference

A distinct nuclear localization signal in the N terminus of Smad 3 determines its ligand-induced nuclear translocation

31 March 2020

1 reference

An extended bipartite nuclear localization signal in Smad4 is required for its nuclear import and transcriptional activity

31 March 2020

1 reference

Transforming growth factor beta-independent shuttling of Smad4 between the cytoplasm and nucleus.

31 March 2020

1 reference

Transforming growth factor-beta induces nuclear import of Smad3 in an importin-beta1 and Ran-dependent manner

31 March 2020

1 reference

Functional mapping of the MH1 DNA-binding domain of DPC4/SMAD4.

31 March 2020

1 reference

Constitutive and IFN-gamma-induced nuclear import of STAT1 proceed through independent pathways

31 March 2020

1 reference

Cell type-specific and tyrosine phosphorylation-independent nuclear presence of STAT1 and STAT3.

31 March 2020

1 reference

A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway

31 March 2020

1 reference

Import and export of the nuclear protein import receptor transportin by a mechanism independent of GTP hydrolysis

31 March 2020

1 reference

CRM1- and Ran-independent nuclear export of beta-catenin.

31 March 2020

1 reference

Nucleocytoplasmic shuttling of Smads 2, 3, and 4 permits sensing of TGF-beta receptor activity

31 March 2020

1 reference

Nuclear export of human beta-catenin can occur independent of CRM1 and the adenomatous polyposis coli tumor suppressor

31 March 2020

1 reference

CRM1 is an export receptor for leucine-rich nuclear export signals

31 March 2020

1 reference

Identification of a signal for rapid export of proteins from the nucleus

31 March 2020

1 reference

Protein sequence requirements for function of the human T-cell leukemia virus type 1 Rex nuclear export signal delineated by a novel in vivo randomization-selection assay

31 March 2020

1 reference

Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1

31 March 2020

1 reference

NF-AT activation requires suppression of Crm1-dependent export by calcineurin

31 March 2020

1 reference

Cytoplasmic localization of mitogen-activated protein kinase kinase directed by its NH2-terminal, leucine-rich short amino acid sequence, which acts as a nuclear export signal

31 March 2020

1 reference

Regulation of intracellular dynamics of Smad4 by its leucine-rich nuclear export signal

31 March 2020

1 reference

A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking

31 March 2020

1 reference

The yeast nuclear pore complex: composition, architecture, and transport mechanism

31 March 2020

1 reference

Nuclear-cytoplasmic shuttling of APC regulates beta-catenin subcellular localization and turnover

31 March 2020

1 reference

The APC tumour suppressor has a nuclear export function.

31 March 2020

1 reference

APC-mediated downregulation of beta-catenin activity involves nuclear sequestration and nuclear export

31 March 2020

1 reference

Nuclear export of the APC tumour suppressor controls beta-catenin function in transcription

31 March 2020

1 reference

The ins and outs of APC and beta-catenin nuclear transport

31 March 2020

1 reference

Nuclear export of MAP kinase (ERK) involves a MAP kinase kinase (MEK)-dependent active transport mechanism

31 March 2020

1 reference

Kinetic analysis of translocation through nuclear pore complexes

31 March 2020

1 reference

Beta-catenin translocation into nuclei demarcates the dorsalizing centers in frog and fish embryos

31 March 2020

1 reference

MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

31 March 2020

1 reference

Nuclear localization and regulation of erk- and rsk-encoded protein kinases

31 March 2020

1 reference

Identification of a cytoplasmic-retention sequence in ERK2

31 March 2020

1 reference

Beta-catenin: a key mediator of Wnt signaling

31 March 2020

1 reference

Molecular and functional analysis of cadherin-based adherens junctions

31 March 2020

1 reference

Wnt signaling: a common theme in animal development

31 March 2020

1 reference

SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor

31 March 2020

1 reference

Distinct endocytic pathways regulate TGF-β receptor signalling and turnover

31 March 2020

1 reference

Interaction of MAP kinase with MAP kinase kinase: its possible role in the control of nucleocytoplasmic transport of MAP kinase

31 March 2020

1 reference

Hydrophobic as well as charged residues in both MEK1 and ERK2 are important for their proper docking

31 March 2020

1 reference

A novel regulatory mechanism of MAP kinases activation and nuclear translocation mediated by PKA and the PTP-SL tyrosine phosphatase

31 March 2020

1 reference

PEA-15 mediates cytoplasmic sequestration of ERK MAP kinase

31 March 2020

1 reference

31 March 2020

p53: good cop/bad cop.

1 reference

Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation

31 March 2020

1 reference

Regulation of p53 localization

31 March 2020

1 reference

A bipartite nuclear localization signal is required for p53 nuclear import regulated by a carboxyl-terminal domain

31 March 2020

1 reference

Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion

31 March 2020

1 reference

Parc: a cytoplasmic anchor for p53.

31 March 2020

1 reference

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

31 March 2020

1 reference

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

31 March 2020

1 reference

The MDM2 RING-finger domain is required to promote p53 nuclear export

31 March 2020

1 reference

An intact HDM2 RING-finger domain is required for nuclear exclusion of p53.

31 March 2020

1 reference

Identification of p53 sequence elements that are required for MDM2-mediated nuclear export

31 March 2020

1 reference

C-terminal ubiquitination of p53 contributes to nuclear export

31 March 2020

1 reference

Mono- versus polyubiquitination: differential control of p53 fate by Mdm2.

31 March 2020

1 reference

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

31 March 2020

1 reference

Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus

31 March 2020

1 reference

Nuclear localization of beta-catenin by interaction with transcription factor LEF-1

31 March 2020

1 reference

Crystal structure of a beta-catenin/Tcf complex

31 March 2020

1 reference

Structural basis of the Axin-adenomatous polyposis coli interaction

31 March 2020

1 reference

A transcriptional partner for MAD proteins in TGF-beta signalling

31 March 2020

1 reference

A self-enabling TGFbeta response coupled to stress signaling: Smad engages stress response factor ATF3 for Id1 repression in epithelial cells.

31 March 2020

1 reference

Crystal Structure of a Phosphorylated Smad2

31 March 2020

1 reference

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

31 March 2020

1 reference

Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes

31 March 2020

1 reference

Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription

31 March 2020

1 reference

Mechanisms of Wnt signaling in development

31 March 2020

1 reference

Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex

31 March 2020

1 reference

Physiological regulation of [beta]-catenin stability by Tcf3 and CK1epsilon

31 March 2020

1 reference

Wnt signals are transmitted through N-terminally dephosphorylated beta-catenin

31 March 2020

1 reference

Two co-existing mechanisms for nuclear import of MAP kinase: passive diffusion of a monomer and active transport of a dimer.

31 March 2020

1 reference

Increased and altered DNA binding of human p53 by S and G2/M but not Gl cyclin-dependent kinases

31 March 2020

1 reference

Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain

31 March 2020

1 reference

A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation

31 March 2020

1 reference

DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization

31 March 2020

1 reference

Regulation of the specific DNA binding function of p53

31 March 2020

1 reference

Phosphorylation of Serine 392 Stabilizes the Tetramer Formation of Tumor Suppressor Protein p53

31 March 2020

1 reference

Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors

31 March 2020

1 reference

Proteomic analysis of the mammalian nuclear pore complex

31 March 2020

1 reference

Nuclear pore complexes: dynamics in unexpected places

31 March 2020

1 reference

Nuclear pore complexes exceeding eightfold rotational symmetry

31 March 2020

1 reference

Architecture of the Xenopus nuclear pore complex revealed by three-dimensional cryo-electron microscopy.

31 March 2020

1 reference

Three-dimensional architecture of the isolated yeast nuclear pore complex: functional and evolutionary implications

31 March 2020

1 reference

RanGAP1 induces GTPase activity of nuclear Ras-related Ran

31 March 2020

1 reference

Co-activation of RanGTPase and inhibition of GTP dissociation by Ran-GTP binding protein RanBP1

31 March 2020

1 reference

Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1

31 March 2020

1 reference

Gradient of increasing affinity of importin beta for nucleoporins along the pathway of nuclear import

31 March 2020

1 reference

31 March 2020

1 reference

An LDL-receptor-related protein mediates Wnt signalling in mice

31 March 2020

1 reference

arrow encodes an LDL-receptor-related protein essential for Wingless signalling

31 March 2020

1 reference

TGF-beta signal transduction

31 March 2020

1 reference

Mechanism of activation of the TGF-beta receptor

31 March 2020

1 reference

Regulation of Smad activity

31 March 2020

1 reference

Human Smad3 and Smad4 are sequence-specific transcription activators

31 March 2020

1 reference

An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control

31 March 2020

1 reference

ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

31 March 2020

1 reference

The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product

31 March 2020

1 reference

Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro

31 March 2020

1 reference

Raf-1 activates MAP kinase-kinase

31 March 2020

1 reference

Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases

31 March 2020

1 reference

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

31 March 2020

1 reference

MAP kinase-mediated signalling to nucleosomes and immediate-early gene induction

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRM1331

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14991001%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

1 reference