(Q40343230)

19 September 2017

title

Tetraspanin KAI1/CD82 suppresses invasion by inhibiting integrin-dependent crosstalk with c-Met receptor and Src kinases (English)

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19 September 2017

Sridhar SC

1

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19 September 2017

Miranti CK

series ordinal

2

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19 September 2017

language of work or name

English

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publication date

1 April 2006

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19 September 2017

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19 September 2017

volume

25

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19 September 2017

issue

16

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19 September 2017

page(s)

2367-2378

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Characterization of integrin-tetraspanin adhesion complexes: role of tetraspanins in integrin signaling

19 September 2017

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SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling

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Quality control of transmembrane domain assembly in the tetraspanin CD82

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Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration

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7 January 2021

The Met receptor and alpha 6 beta 4 integrin can function independently to promote carcinoma invasion

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Recent insights into the role of integrins in cancer metastasis.

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Integrin-mediated RON growth factor receptor phosphorylation requires tyrosine kinase activity of both the receptor and c-Src

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Targeting the HGF/SF receptor c-met using a hammerhead ribozyme transgene reduces in vitro invasion and migration in prostate cancer cells

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Unique expression pattern of the alpha6beta4 integrin and laminin-5 in human prostate carcinoma

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Immunohistochemical comparative analysis of transforming growth factor alpha, epidermal growth factor, and epidermal growth factor receptor in normal, hyperplastic and neoplastic human prostates

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Isomer-specific activity of dichlorodyphenyltrichloroethane with estrogen receptor in adult and suckling estrogen reporter mice.

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Molecular advances in prostate cancer.

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7 January 2021

KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2

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7 January 2021

Newest findings on the oldest oncogene; how activated src does it

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7 January 2021

FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth

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7 January 2021

Tetraspanin CD82 attenuates cellular morphogenesis through down-regulating integrin alpha6-mediated cell adhesion

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7 January 2021

Integrin associated proteins

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7 January 2021

Specific tetraspanin functions

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7 January 2021

Tetraspanin Proteins Mediate Cellular Penetration, Invasion, and Fusion Events and Define a Novel Type of Membrane Microdomain

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7 January 2021

Differential regulation of cell motility and invasion by FAK

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7 January 2021

Correlation of reduction in MRP-1/CD9 and KAI1/CD82 expression with recurrences in breast cancer patients

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7 January 2021

Metastasis-suppressor KAI1/CD82 induces homotypic aggregation of human prostate cancer cells through Src-dependent pathway

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7 January 2021

CAS/Crk coupling serves as a "molecular switch" for induction of cell migration

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7 January 2021

Prostate cancer and the met hepatocyte growth factor receptor

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7 January 2021

High expression of the Met receptor in prostate cancer metastasis to bone

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7 January 2021

Signaling through the tetraspanin CD82 triggers its association with the cytoskeleton leading to sustained morphological changes and T cell activation.

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7 January 2021

Overexpression of sprouty 2 inhibits HGF/SF-mediated cell growth, invasion, migration, and cytokinesis.

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7 January 2021

KAI1 COOH-terminal interacting tetraspanin (KITENIN), a member of the tetraspanin family, interacts with KAI1, a tumor metastasis suppressor, and enhances metastasis of cancer

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7 January 2021

Isolation of monoclonal antibodies that recognize the transforming proteins of avian sarcoma viruses

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7 January 2021

KAI1 metastasis suppressor gene is frequently down-regulated in cervical carcinoma

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7 January 2021

Frequent Down-Regulation and Lack of Mutation of the KAI1 Metastasis Suppressor Gene in Epithelial Ovarian Carcinoma

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7 January 2021

Effects of KAI1/CD82 on biological behavior of human colorectal carcinoma cell line

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7 January 2021

Application of cell adhesion to study signaling networks

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209269

7 January 2021

Sensing the environment: a historical perspective on integrin signal transduction

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7 January 2021

Mutation and expression of the metastasis suppressor gene KAI1 in esophageal squamous cell carcinoma

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7 January 2021

Integrin-induced epidermal growth factor (EGF) receptor activation requires c-Src and p130Cas and leads to phosphorylation of specific EGF receptor tyrosines

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7 January 2021

Integrins induce activation of EGF receptor: role in MAP kinase induction and adhesion-dependent cell survival

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7 January 2021

Tumorigenesis mediated by MET mutant M1268T is inhibited by dominant-negative Src.

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7 January 2021

Prostate stromal cell-derived hepatocyte growth factor induces invasion of prostate cancer cell line DU145 through tumor-stromal interaction

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7 January 2021

Regulation of invasive potential of human prostate cancer cell lines by hepatocyte growth factor

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7 January 2021

Attenuation of EGF receptor signaling by a metastasis suppressor, the tetraspanin CD82/KAI-1

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7 January 2021

Tetraspanin CD82 regulates compartmentalisation and ligand-induced dimerization of EGFR.

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7 January 2021

Glycosylation effect on membrane domain (GEM) involved in cell adhesion and motility: a preliminary note on functional alpha3, alpha5-CD82 glycosylation complex in ldlD 14 cells

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7 January 2021

Regulation of mRNA and protein levels of beta1 integrin variants in human prostate carcinoma

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7 January 2021

c-met proto-oncogene expression in benign and malignant human prostate tissues

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7 January 2021

A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

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7 January 2021

Suppression of human melanoma cell growth and metastasis by the melanoma‐associated antigen CD63 (ME491)

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209269

7 January 2021

c-Src kinase activity is required for hepatocyte growth factor-induced motility and anchorage-independent growth of mammary carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209269

7 January 2021

Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209269

7 January 2021

Different phenotypes in human prostate cancer: alpha6 or alpha3 integrin in cell-extracellular adhesion sites

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209269

7 January 2021

The metastasis suppressor gene C33/CD82/KAI1 induces apoptosis through reactive oxygen intermediates

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209269

7 January 2021

RNA interference reveals that ligand-independent met activity is required for tumor cell signaling and survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209269

7 January 2021

FAK integrates growth-factor and integrin signals to promote cell migration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209269

7 January 2021

Aneusomy of chromosomes 7, 8, and 17 and amplification of HER-2/neu and epidermal growth factor receptor in Gleason score 7 prostate carcinoma: a differential fluorescent in situ hybridization study of Gleason pattern 3 and 4 using tissue microarray

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209269

7 January 2021

Stimulation of beta1 integrins on fibroblasts induces PDGF independent tyrosine phosphorylation of PDGF beta-receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209269

7 January 2021

Suppression of invasive properties of colon cancer cells by a metastasis suppressor KAI1 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209269

7 January 2021

PTEN gene and integrin signaling in cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209269

7 January 2021

Coordination of cell polarization and migration by the Rho family GTPases requires Src tyrosine kinase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209269

7 January 2021

A signaling adapter function for alpha6beta4 integrin in the control of HGF-dependent invasive growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209269

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209269

7 January 2021

Intermediate cells in normal and malignant prostate epithelium express c-MET: implications for prostate cancer invasion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209269

7 January 2021

Clustering of MHC-peptide complexes prior to their engagement in the immunological synapse: lipid raft and tetraspan microdomains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209269

7 January 2021

Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209269

7 January 2021

Activation of the Met receptor by cell attachment induces and sustains hepatocellular carcinomas in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209269

7 January 2021

Cellular adherence elicits ligand-independent activation of the Met cell-surface receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209269

7 January 2021

SRC-mediated phosphorylation of focal adhesion kinase couples actin and adhesion dynamics to survival signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209269

7 January 2021

Frequent downregulation of the KAI1(CD82) metastasis suppressor protein in human cancer cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209269

7 January 2021

Tetraspanin proteins as organisers of membrane microdomains and signalling complexes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209269

7 January 2021

Transmembrane-4 superfamily proteins associate with activated protein kinase C (PKC) and link PKC to specific beta(1) integrins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209269

7 January 2021

Requirement of the p130CAS-Crk Coupling for Metastasis Suppressor KAI1/CD82-mediated Inhibition of Cell Migration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209269

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209269

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Dimensions Publication ID

19 September 2017

1008585207

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