neuro

86 Pins
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7mo
The Effects of Exercise on Dopamine Neurotransmission in Parkinson’s Disease: Targeting Neuroplasticity to Modulate Basal Ganglia Circuitry
Dopamine (DA) projections play a critical role in modulating both motor and cognitive circuits. Dopamine (DA) from neurons within the substantia nigra pars compacta and ventral tegmental area of the midbrain project to the dorsal lateral striatum of the basal ganglia and the prefrontal cortex, respectively. The earlier and more profound depletion of DA in the dorsal lateral striatum results in impairment in corticostriatal thalamic circuitry, which is important for automatic movements, and conse